Keyword - Acetylcholine receptor inhibiting toxin (KW-0008)
Toxin which interferes with the function of the nicotinic acetylcholine receptor (nAChR). The nAChR is a postsynaptic membrane protein that undergoes an extensive conformational change upon binding to acetylcholine, leading to opening of an ion-conducting channel across the plasma membrane. These toxins are mostly found in snake and cone snail venoms.
- nAChR inhibitor
- Nicotinic AChR inhibitor