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Host transcription shutoff by virus

Viral protein involved in inhibiting host transcription to ensure the shutoff of cellular proteins expression and give virus transcripts a competitive edge for access to the cellular translation machinery. Preventing the expression of host proteins is also a strategy to counteract the antiviral response. Inhibition of transcription can be performed by interfering with host RNA pol-II function or interfering with general transcription factors.

Category: Biological process · UniProtKB (16,938)

Inhibition of host transcription initiation by virus

Viral protein involved in the disruption of the host transcriptional machinery. Viruses have evolved ways of interacting with the cellular preinitiation complex (PIC) to shutoff host transcription initiation. For example, the TATA binding protein and TFIIH are targeted by some viral proteins and thus cannot assemble properly to form a functional PIC.

Category: Biological process · UniProtKB (11)

Transcription

Protein involved in the transfer of genetic information from DNA to messenger RNA (mRNA) by DNA-directed RNA polymerase. In the case of some RNA viruses, protein involved in the transfer of genetic information from RNA to messenger RNA (mRNA) by RNA-directed RNA polymerase.

Category: Biological process · UniProtKB (932,837)

Transcription antitermination

Protein involved in transcription antitermination, the process whereby RNA polymerase is allowed to read through specific RNA secondary structures that normally terminate transcription.

Category: Biological process · UniProtKB (5,911)

Transcription regulation

Protein involved in the regulation of the transcription process.

Category: Biological process · UniProtKB (862,573)

Transcription termination

Protein involved in transcription termination.

Category: Biological process · UniProtKB (18,439)

Viral transcription

Viral Protein involved in the synthesis of messenger RNAs. The process can occur in the host cell nucleus or cytoplasm, and the genomic template can be viral DNA or RNA, single- or double-stranded.

Category: Biological process · UniProtKB (1)

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