Protein produced by programmed ribosomal frameshifting, a translational recoding mechanism which causes the ribosome to alter its reading of the genetic code to produce either an alternative product not directly encoded by the mRNA or two or more different isoforms.
Category: Coding sequence diversity · UniProtKB (34,812)
Protein of the ribosome, large ribonucleoprotein particles where the translation of messenger RNA (mRNA) into protein occurs. They are both free in the cytoplasm and attached to membranes of eukaryotic and prokaryotic cells. Ribosomes are also present in all plastids and mitochondria, where they translate organelle-encoded mRNA.
Category: Molecular function · UniProtKB (499,478)
Protein produced by ribosomal 'skipping', in which a specific sequence in the nascent peptide chain prevents the ribosome from creating the peptide bond with the next proline. Nevertheless, translation continues and gives rise to a second chain. This mechanism results in apparent co-translational cleavage of the polyprotein. This process is induced by a '2A-like', or CHYSEL (cis-acting hydrolase element) sequence.
Category: Coding sequence diversity