Keyword
Two-component regulatory system
| Definition | Protein involved in a system responding to environmental changes characterized usually by a sensor kinase in the cell membrane that phosphorylates itself in response to a signal and a response regulator to which the phosphoryl group is transferred. The responder is typically a DNA-binding protein that regulates transcription. Several of these systems are quite complex, involving many proteins in a signaling cascade or contributing to several responses simultaneously. They are involved in a variety processes such as chemotaxis, osmoregulation, magnesium transport, pH tolerance, sporulation, or response of virulent species to host cell's environments. |
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| Synonyms |
Two-component system
Phosphorelay system
Phospho-relay system
Two-component sensory transduction system
Two-component signal transduction system
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| Category |
› Biological process
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