Keyword
Complement pathway
| Definition | Pathway which activates the proteins of the complement system, a group of blood proteins of the globulin class involved in the lysis of foreign cells after they have been coated with antibody, and which also promote the removal of antibody-coated foreign particles by phagocytic cells. The pathway proceeds by a cascade reaction of successive binding and proteolytic cleavage of complement components. This pathway can be activated by either IgG or IgM binding to an antigen. |
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| Synonyms |
Classical complement pathway
Complement activation classical pathway
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| Category |
› Biological process
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| Gene Ontology |
› complement activation, classical pathway [ GO:0006958 ]
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