This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.
The ‘Site’ subsection is frequently used for:
1. Cleavage sites
When the protease is known, it is specified:
Autocatalytic cleavages are specified:
Related keyword: Autocatalytic cleavage
2. Inhibitory sites for proteases
When the protease that is subject to inhibition is known, it is specified:
Related keyword: Protease inhibitor
3. Breakpoint sites for fusion proteins due to chromosomal rearrangement
Related keyword: Chromosomal rearrangement
Each ‘Site’ subsection may refer to a single amino acid or to a peptide bond, which is represented by the positions of the two flanking amino acids.