Last modified October 4, 2013
This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.
The ‘Site’ subsection is frequently used for:
1. Cleavage sites
When the protease is known, it is specified:
Autocatalytic cleavages are specified:
Related keyword: Autocatalytic cleavage
2. Inhibitory sites for proteases
When the protease that is subject to inhibition is known, it is specified:
Related keyword: Protease inhibitor
3. Breakpoint sites for fusion proteins due to chromosomal rearrangement
Related keyword: Chromosomal rearrangement
Each ‘Site’ subsection may refer to a single amino acid or to a peptide bond, which is represented by the positions of the two flanking amino acids.