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Protein domains and families

Last modified September 12, 2013

The task of assigning proteins to families makes use of a range of sources including protein family databases, sequence analysis tools, scientific literature and sequence similarity search tools.

UniProtKB/Swiss-Prot document: Sequence similarities: index
UniProtKB/Swiss-Prot document: Uncharacterized protein families
User manual: Family and Domains section
User manual: Sequence similarities
User manual: Domain
Family and domain databases

How is orthology established in UniProtKB/Swiss-Prot?
How is protein family membership assigned in UniProtKB?