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Lists of specific protein families

Last modified February 10, 2017

7-transmembrane G-linked receptors

7-transmembrane G-linked receptors (also known as G protein coupled receptors (GPCRs), seven-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor and G protein-linked receptors (GPLR)) constitute a large protein family of receptors that sense molecules outside the cell and activate inside signal transduction pathways and cellular responses.

UniProtKB/Swiss-Prot document: List of 7-transmembrane G-linked receptor entries
Related keyword: G-protein coupled receptor

Aminoacyl-tRNA synthetases

Aminoacyl-tRNA synthetases are enzymes that activate an amino acid for translation by forming an aminoacyladenylate intermediate and then link this activated amino acid to the corresponding tRNA molecule. In general, a specific aminoacyl-tRNA synthetase is available for the 20 amino acids.

UniProtKB/Swiss-Prot document: List of aminoacyl-tRNA synthetase entries
Related keyword: Aminoacyl-tRNA synthetase

Intein-containing proteins

Protein splicing is defined as the excision of an intervening protein sequence (the intein) from a protein precursor and the concomitant ligation of the flanking protein fragments (the exteins) to form a mature extein protein and the free intein. Protein splicing results in a native peptide bond between the ligated exteins.

UniProtKB/Swiss-Prot document: List of intein-containing protein entries
Related keyword: Protein splicing

Translation initiation factors

Translation initiation factors are proteins that bind to the small subunit of the ribosome during the initiation of translation, a part of protein biosynthesis.

UniProtKB/Swiss-Prot document: List of translation initiation factor entries
Related keyword: Initiation factor

Uncharacterized protein families (UPF)

Uncharacterized proteins which share regions of similarities are classified as ‘Uncharacterized protein families (UPF)’ according to the Prosite database.

UniProtKB/Swiss-Prot document: List of uncharacterized protein family (UPF) entries