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Help Results

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3D-structure annotation in UniProtKB/Swiss-Prot

Documents about 3D-structure annotation in UniProtKB/Swiss-Prot

Annotation guidelines

Standard operating procedure, protein naming, protein existence

Automatic annotation

Biocuration in UniProt

Manual and automatic annotation in the UniProt Knowledgebase

Controlled vocabulary

Controlled vocabularies used for biocuration in UniProtKB: keywords, taxonomy, human diseases, subcellular location, pathways etc.


C.albicans, S.pombe, S.cerevisiae (yeast): lists of reviewed entries

Homo sapiens

Various documents related to reviewed human entries (incl. protein lists by chromosome)


Caenorhabditis elegans, Dictyostelium discoideum, drosophila: lists of reviewed entries

UniProt key staff

UniProt key staff members

Lists of specific proteins

G-linked receptors, inteins, uncharacterized protein family classification (UPF), etc.


Various documents related to reviewed mouse entries

Nomenclature/classification of specific proteins

Allergens, glycosyl hydrolases, human blood group antigens, kinases, ribosomal proteins etc.


Arabidopsis thaliana, rice: lists of reviewed entries


Lists of reviewed entries for various prokaryotes.

Protein domains and families

Documents about protein domains and families

SAAS (Statistical Automatic Annotation System)

Automatically generated rules for automatic functional annotation in UniProtKB/TrEMBL, based on expertly annotated entries in UniProtKB/Swiss-Prot using C4.5 decision trees

Submissions and updates

How to submit data.


Overview of the UniProt Knowledgebase.


Automatic annotation rules generated by expert biocurators, based on experimental data from manually annotated entries

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