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Provides a stable way of identifying UniProtKB entries

Active site

Amino acid(s) directly involved in the activity of an enzyme

Allergenic properties

Information relevant to allergenic proteins

Alternative products

Description of the different proteins generated from the same gene

Annotation score

Annotation scores provide a measure of how much annotation has been associated with a given entry or proteome.

Binary interactions

Information relevant to binary protein-protein interactions

Binding site

Binding site for any chemical group (co-enzyme, prosthetic group, etc.)

Biophysicochemical properties

Description of biophysical and physicochemical properties

Biotechnological use

The use of a specific protein in the biotechnological industry

Calcium binding

Denotes the position(s) of calcium binding region(s) within the protein


Covalently attached glycan group(s)

Catalytic activity

Description of the reaction(s) catalyzed by an enzyme


Warning about possible errors and/or grounds for confusion


Extent of a polypeptide chain in the mature protein


Description of non-protein substance required by an enzyme to be active

Coiled coil

Denotes the positions of regions of coiled coil within the protein

Compositional bias

Region of compositional bias in the protein

Sequence conflict

Description of sequence discrepancies of unknown origin

Cross-references section

Cross-references that point to data collections other than UniProtKB


Residues participating in covalent linkage(s) between proteins

Developmental stage

Description of how the expression of a gene varies according to the stage of cell, tissue or organism development

Disruption phenotype

Description of the effects caused by the disruption of a protein-encoding gene.

Disulfide bond

Cysteine residues participating in disulfide bonds

DNA binding

Denotes the position and type of a DNA-binding domain


Denotes the position and type of each modular protein domain


Description of the domain(s) present in a protein

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