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TrEMBL release 6.0

Published June 1, 1998


                            TREMBL Release Notes
                            Release 6, June 1998


        EMBL Outstation
        European Bioinformatics Institute (EBI)
        Wellcome Trust Genome Campus
        Hinxton
        Cambridge CB10 1SD
        United Kingdom

        Telephone: (+44 1223) 494 400
        Fax: (+44 1223) 494 468
        Electronic mail address: DATALIB@EBI.AC.UK
        WWW server: http://www.ebi.ac.uk/

        Amos Bairoch
        Medical Biochemistry Department
        Centre Medical Universitaire
        1211 Geneva 4
        Switzerland

        Telephone: (+41 22) 784 40 82
        Fax: (+41 22) 702 55 02
        Electronic mail address: BAIROCH@CMU.UNIGE.CH
        WWW server: http://www.expasy.ch/


  INTRODUCTION
  ============

  TREMBL is a protein sequence database supplementing the SWISS-PROT
  Protein Sequence Data Bank. TREMBL contains the translations of all
  coding sequences (CDS) present in the EMBL Nucleotide Sequence
  Database not yet integrated in SWISS-PROT. TREMBL can be considered
  as a preliminary section of SWISS-PROT. For all TREMBL entries
  which should finally be upgraded to the standard SWISS-PROT
  quality, SWISS-PROT accession numbers have been assigned.


  RELEASE 6.0 OF TREMBL
  =====================

  This TREMBL release is created from the EMBL Nucleotide Sequence Database
  release 54 and contains 177'757 sequence entries, comprising 48'796'878
  amino acids.

  TREMBL is split in two main sections; SP-TREMBL and REM-TREMBL:

  SP-TREMBL (SWISS-PROT TREMBL) contains the entries (150'329) which should be
  eventually incorporated into SWISS-PROT. SWISS-PROT accession numbers have
  been assigned for all SP-TREMBL entries.

  SP-TREMBL is organized in subsections:

  arc.dat (Archea):               5556 entries  (new section)
  fun.dat (Fungi):                4781 entries
  hum.dat (Human):                6312 entries
  inv.dat (Invertebrates):       20364 entries
  mam.dat (Other Mammals):        2450 entries
  mhc.dat (MHC proteins):         3524 entries
  org.dat (Organelles):          11685 entries
  phg.dat (Bacteriophages):       1240 entries
  pln.dat (Plants):              11217 entries
  pro.dat (Prokaryotes):         32000 entries
  rod.dat (Rodents):              5913 entries
  unc.dat (Unclassified):           88 entries
  vrl.dat (Viruses):             41882 entries
  vrt.dat (Other Vertebrates):    3317 entries

  REM-TREMBL (REMaining TREMBL) contains the entries (27'428) that we do
  not want to include in SWISS-PROT.


  WEEKLY UPDATES OF TREMBL AND NON-REDUNDANT DATA SETS
  ====================================================

  Weekly cumulative updates of TREMBL are available by anonymous FTP and
  from the EBI SRS server.

  We also produce every week a complete non-redundant protein sequence
  collection by providing three compressed files (these are in the directory
  /pub/databases/sp_tr_nrdb on the EBI FTP server):
  sprot.dat.Z, trembl.dat.Z and trembl_new.dat.Z.


  ACCESS/DATA DISTRIBUTION
  ========================

  FTP server:     ftp.ebi.ac.uk/pub/databases/trembl
  SRS server:     http://srs.ebi.ac.uk:5000/

  TREMBL is also available on the SWISS-PROT CD-ROM.
  SWISS-PROT + TREMBL is searchable on the FASTA3, BLAST2 and Bic_sw servers
  of the EBI.

  TREMBL HAS BEEN PREPARED BY:
  ============================

  Rolf Apweiler, Christian Desaintes, Sergio Contrino, Wolfgang Fleischmann,
  Henning Hermjakob, Vivien Junker, Stephanie Kappus, Fiona Lang, Michele
  Magrane, Maria Jesus Martin, Steffen Moeller, Nicoletta Mitaritonna and
  Claire O'Donovan at the EMBL Outstation - European Bioinformatics Institute
  (EBI) in Hinxton, UK;
  Amos Bairoch and Alain Gateau at the Medical Biochemistry Department of
  the University of Geneva, Switzerland.

  Notes
  =====

  This manual and the database it accompanies may be copied and redistributed
  freely, without advance permission, provided that this statement is reproduced
  with each copy.


  Citation
  ========

 If you  want to  cite  TREMBL  in  a  publication  please  use  the following
 reference:

           Bairoch A., and Apweiler R.
           The SWISS-PROT protein sequence data bank and its
           supplement TREMBL in 1998.
           Nucleic Acids Res. 26:38-42(1998).