ATP-dependent chromatin assembly factor large subunit - Drosophila melanogaster (Fruit fly)

Sequence

>tr|Q9Y0W1|Q9Y0W1_DROME ATP-dependent chromatin assembly factor large subunit OS=Drosophila melanogaster GN=Acf1 PE=2 SV=1 MPICKREGFDLNQKEGKNETFHDNDQVFCCYITKRIFRDYEHYFRHVMVINSTVWQCEAT GKENLTYEEAVKSERAARKKMEQFKQSLRAPVLLVVEHAQQSAVNTLNMIVAKFLRKRYF IGEEVSVQAKKNATYTVLGVKLDKNMPEPLNGIYEDTDNLVYRLRPNKGDPSAELDLPFR QLRRSRMEFNLENLSMFIKSNVSRVDGLLRPKPEAYKQYVTNPGVNFSTIFIGKMPRYSP AKIKKPDGKKQSTLNKYIVAGEATAAKSKAKAKSDAKSLAEELERVKREKEAKLIELEKQ KAEKKAQLIERVENECNLLLQKTDDLERTDQKVLPRYRQIVTLLPEHLLGDAFMMREFMH TYTGLLSGIEVFRQNLSFYEMTRALTAREIAGPLSDILLVLLGTVFDLQKEEEEECAVTY LDRAAQTQEPYWSMAQAAKSHLYAKRHFSFKVNELPLDALTLSEVLRLHLLGSGAFVNEK AERWRVMYRNGYSSKEDPGLELRLEHSHILRILKNHSVYQLKFKDIMLLIRCLMSQIMTY SGTINLIEERMEQTAKARQDLRALVVGENKRLAAVEINRKKLTQMHHLEVNGVEPEKREA LVEKLKKSIAELHAQSDQQHRKHELQMLKLHSQLFNFLVYLGMDRCYRKYYVLESMPGIF VEHSPDSLDTCLEQPITNKSQIEIRQQSALPKNRKDLRVYLLKLYGDDEKKTKKKAKHSL ENKENQEHRLNGSAEPMDVESNSPEAPTHFELLMCSGDKRSCIVHDSRNGQRQRWAYIYK AEEIDELIKALNPNGLREYELLQELSVLRSLIEQHAKTCPVDLLSLENETMRKKFMAAME SETNRKYGEANFGLPNGTDLNEVMRLHLVDRIIQFENDIYTGDLGRLKVKDMEKWRSDLL GGNYDAQCKLQWGPGGKLEDEAGSDNESHETHEEDDGALLGKYARKPYRDPGMYLAASAD TKPLPDSDDEEDQHTNAVLIPIAVHNMASALLQVEQAIGKRFLKEPYGMKKWDPKQEALK LACDSRLHQWEVSLMESTSFAQVFLHLNILHDCIQWRRSTNKSLCKVCRRGSDPEKMLLC DECNAGTHMFCLKPKLRSVPPGNWYCNDCVKSLGLSHGQNEKDKKQATKKKRKFIVEEED DEATDEEEEEKKDDDMTDEDAEHENEKHDEDVEDDESVTSTPSSSRVNGRILRRPRTRPT SRRLTSKEIEEHAQEDVDSGDVSDDASLTAGEDTIEDESDEEKVCQKCFYDGGEIKCVQC RLFFHLECVHLKRPPRTDFVCKTCKPMPQRPRRRHSNMNGDHDRDEEEPKAKRPRNSLRL SIDKTARPSNGNNNNNNNNSSVNNNNHRRSGRRTNEHMPLNSAALYDLLEQIMKHKAAWP FLRPVLTSEVPDYHQIIKTPMDLAKIKSKLNMGAYQLNEELLSDIQLVFRNCDLYNVEGN EIYDAGCQLERFVIDRCRDMQLPFRPSDMNGEVKAC

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Unreviewed, UniProtKB/TrEMBL Q9Y0W1 (Q9Y0W1_DROME)

Last modified October 14, 2008. Version 44. History...

Clusters with 100%, 90%, 50% identity |

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Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
ATP-dependent chromatin assembly factor large subunit EMBL AAD38952.1

Gene names

Name:	Acf1 EMBL AAD38952.1
ORF Names:	CG1966 FlyBase FBgn0027620

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL AAD38952.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1476 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Domain	Zinc-finger Spearmint SPM001965
Ligand	Metal-binding Zinc
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dendrite morphogenesis Inferred from mutant phenotype. Source: FlyBase epidermis development Inferred from mutant phenotype. Source: FlyBase muscle development Inferred from mutant phenotype. Source: FlyBase nucleosome assembly Ref.1 Inferred from direct assay. Source: FlyBase nucleosome mobilization Inferred from direct assay. Source: FlyBase nucleosome positioning Inferred from direct assay. Source: FlyBase regulation of transcription, DNA-dependent Inferred from direct assay. Source: FlyBase
Cellular component	ACF complex Ref.1 Inferred from direct assay. Source: FlyBase chromatin accessibility complex Inferred from direct assay. Source: FlyBase
Molecular function	DNA binding Traceable author statement. Source: FlyBase
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q9Y0W1-1 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: C18A6CEBF57E66B3
Show »

1,476

170,459

        10         20         30         40         50         60 
MPICKREGFD LNQKEGKNET FHDNDQVFCC YITKRIFRDY EHYFRHVMVI NSTVWQCEAT 

        70         80         90        100        110        120 
GKENLTYEEA VKSERAARKK MEQFKQSLRA PVLLVVEHAQ QSAVNTLNMI VAKFLRKRYF 

       130        140        150        160        170        180 
IGEEVSVQAK KNATYTVLGV KLDKNMPEPL NGIYEDTDNL VYRLRPNKGD PSAELDLPFR 

       190        200        210        220        230        240 
QLRRSRMEFN LENLSMFIKS NVSRVDGLLR PKPEAYKQYV TNPGVNFSTI FIGKMPRYSP 

       250        260        270        280        290        300 
AKIKKPDGKK QSTLNKYIVA GEATAAKSKA KAKSDAKSLA EELERVKREK EAKLIELEKQ 

       310        320        330        340        350        360 
KAEKKAQLIE RVENECNLLL QKTDDLERTD QKVLPRYRQI VTLLPEHLLG DAFMMREFMH 

       370        380        390        400        410        420 
TYTGLLSGIE VFRQNLSFYE MTRALTAREI AGPLSDILLV LLGTVFDLQK EEEEECAVTY 

       430        440        450        460        470        480 
LDRAAQTQEP YWSMAQAAKS HLYAKRHFSF KVNELPLDAL TLSEVLRLHL LGSGAFVNEK 

       490        500        510        520        530        540 
AERWRVMYRN GYSSKEDPGL ELRLEHSHIL RILKNHSVYQ LKFKDIMLLI RCLMSQIMTY 

       550        560        570        580        590        600 
SGTINLIEER MEQTAKARQD LRALVVGENK RLAAVEINRK KLTQMHHLEV NGVEPEKREA 

       610        620        630        640        650        660 
LVEKLKKSIA ELHAQSDQQH RKHELQMLKL HSQLFNFLVY LGMDRCYRKY YVLESMPGIF 

       670        680        690        700        710        720 
VEHSPDSLDT CLEQPITNKS QIEIRQQSAL PKNRKDLRVY LLKLYGDDEK KTKKKAKHSL 

       730        740        750        760        770        780 
ENKENQEHRL NGSAEPMDVE SNSPEAPTHF ELLMCSGDKR SCIVHDSRNG QRQRWAYIYK 

       790        800        810        820        830        840 
AEEIDELIKA LNPNGLREYE LLQELSVLRS LIEQHAKTCP VDLLSLENET MRKKFMAAME 

       850        860        870        880        890        900 
SETNRKYGEA NFGLPNGTDL NEVMRLHLVD RIIQFENDIY TGDLGRLKVK DMEKWRSDLL 

       910        920        930        940        950        960 
GGNYDAQCKL QWGPGGKLED EAGSDNESHE THEEDDGALL GKYARKPYRD PGMYLAASAD 

       970        980        990       1000       1010       1020 
TKPLPDSDDE EDQHTNAVLI PIAVHNMASA LLQVEQAIGK RFLKEPYGMK KWDPKQEALK 

      1030       1040       1050       1060       1070       1080 
LACDSRLHQW EVSLMESTSF AQVFLHLNIL HDCIQWRRST NKSLCKVCRR GSDPEKMLLC 

      1090       1100       1110       1120       1130       1140 
DECNAGTHMF CLKPKLRSVP PGNWYCNDCV KSLGLSHGQN EKDKKQATKK KRKFIVEEED 

      1150       1160       1170       1180       1190       1200 
DEATDEEEEE KKDDDMTDED AEHENEKHDE DVEDDESVTS TPSSSRVNGR ILRRPRTRPT 

      1210       1220       1230       1240       1250       1260 
SRRLTSKEIE EHAQEDVDSG DVSDDASLTA GEDTIEDESD EEKVCQKCFY DGGEIKCVQC 

      1270       1280       1290       1300       1310       1320 
RLFFHLECVH LKRPPRTDFV CKTCKPMPQR PRRRHSNMNG DHDRDEEEPK AKRPRNSLRL 

      1330       1340       1350       1360       1370       1380 
SIDKTARPSN GNNNNNNNNS SVNNNNHRRS GRRTNEHMPL NSAALYDLLE QIMKHKAAWP 

      1390       1400       1410       1420       1430       1440 
FLRPVLTSEV PDYHQIIKTP MDLAKIKSKL NMGAYQLNEE LLSDIQLVFR NCDLYNVEGN 

      1450       1460       1470 
EIYDAGCQLE RFVIDRCRDM QLPFRPSDMN GEVKAC

References

[1]

"ACF consists of two subunits, Acf1 and ISWI, that function cooperatively in the ATP-dependent catalysis of chromatin assembly."
Ito T., Levenstein M.E., Fyodorov D.V., Kutach A.K., Kobayashi R., Kadonaga J.T.
Genes Dev. 13:1529-1539(1999) [PubMed: 10385622] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
	AF148962 mRNA. Translation: AAD38952.1.
3D structure databases
HSSP	HSSP built from PDB template 1F62 based on UniProtKB Q9UIG0.
ModBase	Search...
Organism-specific databases
FlyBase	FBgn0027620. Acf1.
Gene expression databases
ArrayExpress	Q9Y0W1.
Family and domain databases
InterPro	IPR001487. Bromodomain. IPR004022. DDT. IPR013136. WSTF_Acf1_Cbp146. IPR001965. Znf_PHD. IPR013083. Znf_RING/FYVE/PHD. [Graphical view]
Gene3D	G3DSA:1.20.920.10. Bromodomain. 1 hit. G3DSA:3.30.40.10. Znf_RING/FYVE/PHD. 2 hits.
Pfam	PF00439. Bromodomain. 1 hit. PF00628. PHD. 2 hits. [Graphical view]
PRINTS	PR00503. BROMODOMAIN.
SMART	SM00297. BROMO. 1 hit. SM00571. DDT. 1 hit. SM00249. PHD. 2 hits. [Graphical view]
PROSITE	PS50014. BROMODOMAIN_2. 1 hit. PS50827. DDT. 1 hit. PS51136. WAC. 1 hit. PS01359. ZF_PHD_1. 2 hits. PS50016. ZF_PHD_2. 1 hit. [Graphical view]

Entry information

Entry name

Q9Y0W1_DROME

Accession

Primary (citable) accession number: Q9Y0W1

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	October 14, 2008
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information