Toll-3 - Drosophila melanogaster (Fruit fly)

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Unreviewed, UniProtKB/TrEMBL Q9NBK6 (Q9NBK6_DROME)

Last modified April 8, 2008. Version 35. History...

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Names and origin · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Toll-3 [Fragment] EMBL AAF86229.1

Gene names

Name:	MstProx FlyBase FBgn0015770
ORF Names:	CG1149 FlyBase FBgn0015770

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL AAF86229.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein existence

Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 TIR domain. Spearmint SPM004075

Ontologies

Keywords
Domain	Leucine-rich repeat Spearmint SPM000372 Repeat Spearmint SPM000157
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	innate immune response Inferred from electronic annotation. Source: InterPro signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	intrinsic to membrane Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from electronic annotation. Source: InterPro transmembrane receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Experimental info

Non-terminal residue

1

EMBL AAF86229.1

Sequences

Sequence

Length

Mass (Da)

Tools

Q9NBK6-1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: C8EFA786D7CA9525
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785

91,898

        10         20         30         40         50         60 
SHLRSLTFIG FQIENLSTKP FAQFINLKRM VLTNCTVRNL TFLRTLQKSL EHLELDIDNE 

        70         80         90        100        110        120 
VDLKYFTNFS SLKFMKVRNY IPNKNFTALI CTHKNCNFIR GINGLECPKL CQCLYIIDDL 

       130        140        150        160        170        180 
ELNIDCSNLG LLQIPPLPIP IYGDVKLNFS NNSLSQLPTM TLPGYKLVKR LDVSRNRLTN 

       190        200        210        220        230        240 
LSINHLPAKL DYLDVSFNEI INMGNDVIKY LRTVPIFKQT GNQWTIHCDD KPLLNFFRHL 

       250        260        270        280        290        300 
KLIIRMKSAE MKPMFLHSLT ELPKGFLKFL GKHFIWLGVR KQEYYLINEE QLLQSMHRKL 

       310        320        330        340        350        360 
NNLNTIMSIY KYMEWLHRKL IFVNREYDLF YIRQMAAPCP HKCECCYSRD SLILKIDCRN 

       370        380        390        400        410        420 
KFVYNFPDIV ARNSRLMRKQ NMSSPMELHL SKNNISNITI AMLPKELRFL DLRFNNLVTL 

       430        440        450        460        470        480 
DDKVLSYLKK NSIKTKLSGN PWNCDCKSRS VLSILRDHEP LEYDVTLKRC NISPTDCPDV 

       490        500        510        520        530        540 
CVCCLDNLTW PSFIVDCRGE GLLQMPSLSS RVTYVDLRNN NLTALSQKNR SSIENRSLKL 

       550        560        570        580        590        600 
HLLDNPWSCS CNDIEKINFM KSVSSSIVDF TEIKCSNGEK LVSINQHIVC PSDLFYYLAL 

       610        620        630        640        650        660 
AISLVATIIA LNFLIWFRQP VLVWFYEHGV CLSLAAKREL DKDKRFDAFL AFTHKDEALL 

       670        680        690        700        710        720 
EEFVDRLERG RPRFQLCFYL RDWLAGESIP DCIGQSIKDS RRIIVLMTEN FMNSTWGRLE 

       730        740        750        760        770        780 
FRLALHATSR DRCKRLIVVL YPNVKNFDSL DSELRTYMAF NTYLERSHPN FWNKLIYSMP 


HTKLR

References

[1]	"Toll-related receptors and the control of antimicrobial peptide expression in Drosophila." Tauszig S., Jouanguy E., Hoffmann J.A., Imler J.L. Proc. Natl. Acad. Sci. U.S.A. 97:10520-10525(2000) [PubMed: 10973475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
	AF247769 mRNA. Translation: AAF86229.1.
3D structure databases
HSSP	HSSP built from PDB template 1O77 based on UniProtKB O60603.
ModBase	Search...
Genome annotation databases
Ensembl	CG1149. Drosophila melanogaster. [Contig view]
Organism-specific databases
FlyBase	FBgn0015770. MstProx.
Gene expression databases
ArrayExpress	Q9NBK6.
Family and domain databases
InterPro	IPR004075. IL1_rcpt_1. IPR001611. LRR. IPR000372. LRR_cys_N. IPR000157. TIR. [Graphical view]
Pfam	PF00560. LRR_1. 2 hits. PF01462. LRRNT. 1 hit. PF01582. TIR. 1 hit. [Graphical view]
PRINTS	PR01537. INTRLKN1R1F. PR00019. LEURICHRPT.
SMART	SM00013. LRRNT. 3 hits. SM00255. TIR. 1 hit. [Graphical view]
PROSITE	PS50104. TIR. 1 hit. [Graphical view]

Entry information

Entry name

Q9NBK6_DROME

Accession

Primary (citable) accession number: Q9NBK6

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	April 8, 2008
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information