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Unreviewed, UniProtKB/TrEMBL Q7KNF1 (Q7KNF1_DROME)

Last modified September 23, 2008. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    Ribonuclease (CG8730-PA) (LD20030p) EMBL AAD31170.1
Gene names
Name: drosha EMBL AAD31170.1 FlyBase FBgn0026722
ORF Names: CG8730 FlyBase FBgn0026722, Dmel_CG8730 EMBL AAF59169.1
OrganismDrosophila melanogaster (Fruit fly) [Complete proteome] EMBL AAD31170.1
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

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Protein attributes

Sequence length1327 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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Ontologies

Keywords

   Technical termComplete proteome

Gene Ontology (GO)

   Biological processprimary microRNA processing

Inferred from mutant phenotype. Source: FlyBase

Complete GO annotation...

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Sequences

Sequence LengthMass (Da)Tools
Q7KNF1-1 [UniParc].

Last modified October 3, 2006. Version 1.
Checksum: 84AD3AABD676C9E8

FASTA1,327152,817
        10         20         30         40         50         60 
MYQPPLPPPP VQPAPPPPPP PPEEDLSPPG VGVPSHNYSS NESHSQSSKS LDYVYPETPA 

        70         80         90        100        110        120 
PYASSVPSYD PYQQPPAYGY EGYAYNEQAQ KYGGQESHYQ YQYPASGSSF LYESYKYPDR 

       130        140        150        160        170        180 
YPAYSSNYRP PSERQRYTSN SSSQGYHHYP GYSSGRRYEQ RHDQEHRQIQ DSRYAHEPRH 

       190        200        210        220        230        240 
GHYAHRQAKG SQHGYYGSAA RNQVSDDYSP RGHHERERNE TLEKTRAKPK VETERDRLLR 

       250        260        270        280        290        300 
QWCSNFCEKP EDYVKKMNAL SEADAPVESW VRSSPAELYY ERTKSENEVR GRARLQKLCT 

       310        320        330        340        350        360 
LFDEELLQRA KRVREKLPVY VPPPRKARRR VCKHKHKSEA CSSSSSSDDD SDEDAFKIEQ 

       370        380        390        400        410        420 
DCCMEELSRK VQHPQRVHAD LWHNDAGEMN DGPLCRCSAK SRRIGIRHGI YPGETGYKLC 

       430        440        450        460        470        480 
DPNSNNAGKL FHYRISISPP TNFLTKTPTI IKHDEHEFLF EGFSLLSHVR LSDLPVCKVI 

       490        500        510        520        530        540 
RFNIEYTIEY EEEKMPENFT IHELDIFFKY LFHELLELVD FNLMPNLPSG NVEESCPAFH 

       550        560        570        580        590        600 
FFPRFVRDLP DNGKEVLAMV EVLRYLLDNS AQLVERQQLL HLNQISQSEW QNYVDFIKGM 

       610        620        630        640        650        660 
LVTKPGYKPC SLRVDQLDRN NSDLPECVDR ETGISHPAIV HFGICHPQLS YAGNPEYQKA 

       670        680        690        700        710        720 
WREYVKYRHL MANMSKPSFK DKRKLEEKEQ RLQEMRTQGR MKRNITVAIS SEGFYRTGIM 

       730        740        750        760        770        780 
CDVVQHAMLI PVLTGHLRFH KSLDLLEESI GYRFKNRYLL QLALTHPSYK ENYGTNPDHA 

       790        800        810        820        830        840 
RNSLTNCGIR QPEYGDRKIH YMNTRKRGIN TLVSIMSRFG KEHETVSNIT HNERLEFLGD 

       850        860        870        880        890        900 
AVVEFLSSIH LFFMFPELEE GGLATYRAAI VQNQHLALLA KKLQLEEFML YAHGSDLCHE 

       910        920        930        940        950        960 
LELRHAMANC FEALMGALLL DGGIKVADEV FTDALFRQDE KLLSIWKNLP EHPLQEQEPL 

       970        980        990       1000       1010       1020 
GDRSCIDSYR VLKELTKFED SIGIKFKHIR LLARAFTDRS IGFTHLTLGS NQRLEFLGDT 

      1030       1040       1050       1060       1070       1080 
VLQLICSEYL YRHFPEHHEG HLSLLRSSLV NNRTQAVVCD DLGMPKYAVY ANPKADLKTK 

      1090       1100       1110       1120       1130       1140 
DRADLLEAFL GALYVDKGLL YCEQFCHVCL FPRLQLFIMN QDWNDPKSKL QQCCLTLRTM 

      1150       1160       1170       1180       1190       1200 
DGGEPDIPYY KVVEASGPTN TRVYKVAVYF RSKRLATSSG SSIQQAEMNA AKQALENSRD 

      1210       1220       1230       1240       1250       1260 
LFPQLDHQKR VIAKSIKKQT GNELDNDSDR QHQEEKIKRP KYATPLQDES HLPKQYRMHE 

      1270       1280       1290       1300       1310       1320 
NISSDELPED EDFESTAPKS PTMPLRSNRS GSSSSSSSSD SDGSTSSPKC KRRLKKCSSV 


SSKSSLG

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References

« Hide 'large scale' references
[1]"A novel type of RNase III family proteins in eukaryotes."
Filippov V., Solovyev V., Filippova M., Gill S.S.
Gene 245:213-221(2000) [PubMed: 10713462] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]Filippov V.A., Filippova M.A., Gill S.S.
Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[3]"Phosphoproteome analysis of Drosophila melanogaster embryos."
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.
J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
[4]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[5]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[6]Stapleton M., Carlson J., Chavez C., Frise E., George R., Pacleb J., Park S., Wan K., Yu C., Celniker S.
Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Berkeley EMBL AAY84903.1.
+Additional computationally mapped references.

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Cross-references

Sequence databases

AF116572 mRNA. Translation: AAD31170.1.
AE013599 Genomic DNA. Translation: AAF59169.1.
BT023503 mRNA. Translation: AAY84903.1.
RefSeqNP_477436.1.
UniGeneDm.4482

3D structure databases

HSSPHSSP built from PDB template 1JFZ based on UniProtKB O67082.
ModBaseSearch...

Genome annotation databases

GeneID35747.
KEGGdme:Dmel_CG8730.

Organism-specific databases

FlyBaseFBgn0026722. drosha.

Family and domain databases

InterProIPR001159. Ds_RNA_bd.
IPR014720. dsRNA-bd-like.
IPR000999. RNase_III.
[Graphical view]
Gene3DG3DSA:3.30.160.20. dsRNA-bd-like. 1 hit.
G3DSA:1.10.1520.10. RNase_III. 2 hits.
PfamPF00035. dsrm. 1 hit.
PF00636. Ribonuclease_3. 2 hits.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 2 hits.
[Graphical view]
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 2 hits.
[Graphical view]
ProDomQ7KNF1.
[Graphical view] [Entries sharing at least one domain]

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Entry information

Entry nameQ7KNF1_DROME
AccessionPrimary (citable) accession number: Q7KNF1
Entry history
Integrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: September 23, 2008
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information