G-protein coupled receptor - Drosophila melanogaster (Fruit fly)

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Unreviewed, UniProtKB/TrEMBL Q6WNX8 (Q6WNX8_DROME)

Last modified October 14, 2008. Version 34. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
G-protein coupled receptor EMBL AAQ19543.1

Gene names

ORF Names:

CG8784 FlyBase FBgn0038140

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL AAQ19543.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	658 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. RuleBase RU000688V2

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane RuleBase RU000688V2
Molecular function	G-protein coupled receptor RuleBase RU000688V2 Receptor Transducer
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	neuropeptide receptor activity Ref.1 Inferred from direct assay. Source: FlyBase
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q6WNX8-1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: D0AC482A3E5560F7
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658

72,176

        10         20         30         40         50         60 
MLQGVAITIA NDSNDDGLNQ SFMAHVSPSP NQSPSIGVGI GIASSTMANP SESPEMLLLK 

        70         80         90        100        110        120 
NDKFLTHVAH LLNITTENLS NLLGSTNGTN ASTMAADSPV DESLTLRTAL TVCYALIFVA 

       130        140        150        160        170        180 
GVLGNLITCI VISRNNFMHT ATNFYLFNLA VSDLILLVSG IPQELYNLWY PDMYPFTDAM 

       190        200        210        220        230        240 
CIMGSVLSEM AANATVLTIT AFTVERYIAI CHPFRQHTMS KLSRAIKFIF AIWLAAFLLA 

       250        260        270        280        290        300 
LPQAMQFSVV YQNEGYSCTM ENDFYAHVFA VSGFIFFGGP MTAICVLYVL IGVKLKRSRL 

       310        320        330        340        350        360 
LQSLPRRTFD ANRGLNAQGR VIRMLVAVAV AFFLCWAPFH AQRLMAVYGL NLINIGISRD 

       370        380        390        400        410        420 
AFNDYFRILD YTSGVLYFLS TCINPLLYNI MSHKFREAFK ITLTRQFGLA RNHHHQQSQH 

       430        440        450        460        470        480 
HQHNYSALLR QNGSMRLQPA SCSVNNNALE PYGSYRVVQF RCRDANHQLS LQDSIRTTTT 

       490        500        510        520        530        540 
TTTINSNSMA AGNGVGGGAG GGGRRLRKQE LYGPVPGTAV PHRMLQAQVS QLSSLGDANS 

       550        560        570        580        590        600 
LLEAEVVDRH YASGRAKRAL LATKSGALLV TPPQSGDPSE VSQPATRLKL TRVISRRDEV 

       610        620        630        640        650 
ANASTPPFCG SHSLPDPETC QSASVAGRSS RKFPWRKRRQ KTEDPSSEGL TYGSPKSQ

References

[1]	"Molecular cloning, functional expression, and gene silencing of two Drosophila receptors for the Drosophila neuropeptide pyrokinin-2." Rosenkilde C., Cazzamali G., Williamson M., Hauser F., Sondergaard L., DeLotto R., Grimmelikhuijzen C.J. Biochem. Biophys. Res. Commun. 309:485-494(2003) [PubMed: 12951076] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Rosenkilde C.H., Cazzamali G., Williamson M.R., Grimmelikhuijzen C.J.P. Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
	AY277898 mRNA. Translation: AAQ19543.1.
3D structure databases
ModBase	Search...
Protein family/group databases
GPCRDB	Search...
Organism-specific databases
FlyBase	FBgn0038140. CG8784.
Gene expression databases
ArrayExpress	Q6WNX8.
Family and domain databases
InterPro	IPR000923. BlueCu_1. IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_supfam. [Graphical view]
Pfam	PF00001. 7tm_1. 1 hit. [Graphical view]
PRINTS	PR00237. GPCRRHODOPSN.
PROSITE	PS00196. COPPER_BLUE. 1 hit. Uncertain. PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]

Entry information

Entry name

Q6WNX8_DROME

Accession

Primary (citable) accession number: Q6WNX8

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	October 14, 2008
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information