Unreviewed,
UniProtKB/TrEMBL Q2Q3V6 (Q2Q3V6_DROME)
Last modified
July 22, 2008.
Version 27.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information
Names and origin
| Protein names | Submitted name: Dicer-2 EMBL ABB54750.1 | ||
| Gene names |
| ||
| Organism | Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL ABB54750.1 | ||
| Taxonomic identifier | 7227 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora |
Protein attributes
| Sequence length | 1715 AA. |
| Sequence status | Fragment. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
Ontologies
Keywords | |
|---|---|
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Helicase RuleBase RU000452V3 Hydrolase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | RNA interference, production of siRNA Inferred from direct assay. Source: FlyBase RNA interference, siRNA loading onto RISCInferred from mutant phenotype. Source: FlyBase RNA interference, targeting of mRNA for destructionInferred from mutant phenotype. Source: FlyBase chromatin silencingInferred from mutant phenotype. Source: FlyBase defense response to virusInferred from mutant phenotype. Source: FlyBase |
| Cellular component | cytoplasm Inferred from direct assay. Source: FlyBase nucleusInferred from direct assay. Source: FlyBase |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | |||
Experimental info | |||||||
|---|---|---|---|---|---|---|---|
| Non-terminal residue | 1 | 1 | EMBL ABB54750.1 | ||||
Sequences
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References
| [1] | "Natural selection drives extremely rapid evolution in antiviral RNAi genes." Obbard D.J., Jiggins F.M., Halligan D.L., Little T.J. Curr. Biol. 16:580-585(2006) [PubMed: 16546082] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 191 EMBL ABB54750.1. |
Cross-references
Sequence databases | |
|---|---|
| DQ228797 Genomic DNA. Translation: ABB54750.1. | |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| Ensembl | CG6493. Drosophila melanogaster. [Contig view] |
Organism-specific databases | |
| FlyBase | FBgn0034246. Dcr-2. |
Gene expression databases | |
| ArrayExpress | Q2Q3V6. |
Family and domain databases | |
| InterPro | IPR014001. DEAD-like_N. IPR001650. DNA/RNA_helicase_C. IPR011545. DNA/RNA_helicase_DEAD/DEAH_N. IPR001159. Ds_RNA_bd. IPR005034. DUF283. IPR014021. Helicase_SF1/SF2_ATP-bd. IPR003100. PAZ. IPR000999. RNase_III. [Graphical view] |
| Gene3D | G3DSA:1.10.1520.10. RNase_III. 2 hits. |
| Pfam | PF00270. DEAD. 1 hit. PF00035. dsrm. 1 hit. PF03368. DUF283. 1 hit. PF00271. Helicase_C. 1 hit. PF02170. PAZ. 1 hit. PF00636. Ribonuclease_3. 2 hits. [Graphical view] |
| SMART | SM00487. DEXDc. 1 hit. SM00358. DSRM. 1 hit. SM00490. HELICc. 1 hit. SM00535. RIBOc. 2 hits. [Graphical view] |
| PROSITE | PS50137. DS_RBD. 1 hit. PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. PS50821. PAZ. 1 hit. PS50142. RNASE_3_2. 2 hits. [Graphical view] |
Entry information
| Entry name | Q2Q3V6_DROME | ||||||||
| Accession | Primary (citable) accession number: Q2Q3V6 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||
