Unreviewed,
UniProtKB/TrEMBL Q27IU8 (Q27IU8_DROME)
Last modified
October 14, 2008.
Version 18.
History...
Clusters with 100%,
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Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information
Names and origin
| Protein names | Submitted name: Dicer-1 EMBL ABD61602.1 | ||||
| Gene names |
| ||||
| Organism | Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL ABD61602.1 | ||||
| Taxonomic identifier | 7227 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora |
Protein attributes
| Sequence length | 2043 AA. |
| Sequence status | Fragment. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
Ontologies
Keywords | |
|---|---|
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | RNA interference, production of siRNA Inferred from direct assay. Source: FlyBase RNA interference, siRNA loading onto RISCInferred from mutant phenotype. Source: FlyBase germ-line stem cell divisionInferred from mutant phenotype. Source: FlyBase mitotic cell cycle, embryonicInferred from mutant phenotype. Source: FlyBase pole cell formationInferred from mutant phenotype. Source: FlyBase pre-microRNA processingInferred from mutant phenotype. Source: FlyBase segment polarity determinationInferred from genetic interaction. Source: FlyBase |
| Cellular component | RNA-induced silencing complex Inferred from direct assay. Source: FlyBase cytoplasmInferred from direct assay. Source: FlyBase |
| Molecular function | bidentate ribonuclease III activity Inferred from direct assay. Source: FlyBase protein bindingInferred from physical interaction. Source: FlyBase |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | |||
Experimental info | ||||||||
|---|---|---|---|---|---|---|---|---|
| Non-terminal residue | 1 | 1 | EMBL ABD61602.1 | |||||
| Non-terminal residue | 2043 | 1 | EMBL ABD61602.1 | |||||
Sequences
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References
| [1] | "Natural selection drives extremely rapid evolution in antiviral RNAi genes." Obbard D.J., Jiggins F.M., Halligan D.L., Little T.J. Curr. Biol. 16:580-585(2006) [PubMed: 16546082] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: G130 EMBL ABD61602.1. |
Cross-references
Sequence databases | |
|---|---|
| DQ398886 Genomic DNA. Translation: ABD61602.1. | |
3D structure databases | |
| ModBase | Search... |
Organism-specific databases | |
| FlyBase | FBgn0039016. Dcr-1. |
Gene expression databases | |
| ArrayExpress | Q27IU8. |
Family and domain databases | |
| InterPro | IPR001650. DNA/RNA_helicase_C. IPR005034. DUF283. IPR003100. PAZ. IPR000999. RNase_III. [Graphical view] |
| Gene3D | G3DSA:1.10.1520.10. RNase_III. 2 hits. |
| Pfam | PF03368. DUF283. 1 hit. PF00271. Helicase_C. 1 hit. PF02170. PAZ. 1 hit. PF00636. Ribonuclease_3. 2 hits. [Graphical view] |
| SMART | SM00490. HELICc. 1 hit. SM00535. RIBOc. 2 hits. [Graphical view] |
| PROSITE | PS51194. HELICASE_CTER. 1 hit. PS50821. PAZ. 1 hit. PS00517. RNASE_3_1. 1 hit. PS50142. RNASE_3_2. 2 hits. [Graphical view] |
Entry information
| Entry name | Q27IU8_DROME | ||||||||
| Accession | Primary (citable) accession number: Q27IU8 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||
