CAST - Drosophila melanogaster (Fruit fly)

Sequence

>tr|Q25B55|Q25B55_DROME CAST OS=Drosophila melanogaster GN=brp PE=2 SV=1 MGSPYYRDMDEPTSPAGAGHHRSRSASRPPMAHAMDYPRTRYQSLDRGGLVDPHDREFIP IREPRDRSRDRSLERGLYLEDELYGRSARQSPSAMGGYNTGMGPTSDRAYLGDLQHQNTD LQRELGDLKRELELTNQKLGSSMHSIKTFWSPELKKERAPRKEESAKYSLINDQLKLLST ENQKQAMLVRQLEEELRLRMRQPNLEMRQQMEAIYAENDHLQREISILRETVKDLECRVE TQKQTLIARDESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEIL AMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQ GTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSA MQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRA AESEVEKLQTRPERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQR TARLELENERLKHDLERSQNVQKLMFETGKISTTFGRTTMTTSQELDRAQERADKASAEL RRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQ SGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLD KACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQV QLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQK LQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSR CDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNA RSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEA AHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLDKTLMELETIRG KSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELER AHIEREKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIDRLRDRL EKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAE AEREALRQANRSGGAGAAPHPQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQK ELQNAEAELQKTREENRKLRNGHQVPPVAAPPAGPSPAEFQAMQKEIQTLQQKLQESERA LQAAGPQQAQAAAAAGASREEIEQWRKVIEQEKSRADMADKAAQEMHKRIQLMDQHIKDQ HAQMQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQAACTERDRF QQQLELLVTELEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGAT DVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEFD VQLRKRKEQMDQLEKSLQTQGGGAAAAGELNKKLMDTQRQLEACVKELQNTKEEHKKAAT ETERLLQLVQMSQEEQNAKEKTIMDLQQALKIAQAKVKQAQTQQQQQQDAGPAGFLKSFF

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Unreviewed, UniProtKB/TrEMBL Q25B55 (Q25B55_DROME)

Last modified November 4, 2008. Version 16. History...

Clusters with 100%, 90%, 50% identity |

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Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
CAST EMBL CAH61079.2

Gene names

Name:	brp FlyBase FBgn0083982 FlyBase FBgn0086376 FlyBase FBgn0259246
Synonyms:	Cast EMBL CAH61079.2

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL CAH61079.2

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1740 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	adult locomotory behavior Inferred from mutant phenotype. Source: FlyBase maintenance of presynaptic active zone structure Inferred from mutant phenotype. Source: FlyBase regulation of synaptic plasticity Inferred from mutant phenotype. Source: FlyBase
Cellular component	presynaptic active zone Inferred from direct assay. Source: FlyBase
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q25B55-1 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: DD83FF18F4D6D038
Show »

1,740

201,652

        10         20         30         40         50         60 
MGSPYYRDMD EPTSPAGAGH HRSRSASRPP MAHAMDYPRT RYQSLDRGGL VDPHDREFIP 

        70         80         90        100        110        120 
IREPRDRSRD RSLERGLYLE DELYGRSARQ SPSAMGGYNT GMGPTSDRAY LGDLQHQNTD 

       130        140        150        160        170        180 
LQRELGDLKR ELELTNQKLG SSMHSIKTFW SPELKKERAP RKEESAKYSL INDQLKLLST 

       190        200        210        220        230        240 
ENQKQAMLVR QLEEELRLRM RQPNLEMRQQ MEAIYAENDH LQREISILRE TVKDLECRVE 

       250        260        270        280        290        300 
TQKQTLIARD ESIKKLLEML QAKGMGKEEE RQMFQQMQAM AQKQLDEFRL EIQRRDQEIL 

       310        320        330        340        350        360 
AMAAKMKTLE EQHQDYQRHI AVLKESLCAK EEHYNMLQTD VEEMRARLEE KNRLIEKKTQ 

       370        380        390        400        410        420 
GTLQTVQERN RLTSELTELK DHMDIKDRKI SVLQRKIENL EDLLKEKDNQ VDMARARLSA 

       430        440        450        460        470        480 
MQAHHSSSEG ALTSLEEAIG DKEKQMAQLR DQRDRAEHEK QEERDLHERE VADYKIKLRA 

       490        500        510        520        530        540 
AESEVEKLQT RPERAVTERE RLEIKLEASQ SELGKSKAEL EKATCEMGRS SADWESTKQR 

       550        560        570        580        590        600 
TARLELENER LKHDLERSQN VQKLMFETGK ISTTFGRTTM TTSQELDRAQ ERADKASAEL 

       610        620        630        640        650        660 
RRTQAELRVT QSDAERAREE AAALQEKLEK SQGEVYRLKA KLENAQGEQE SLRQELEKAQ 

       670        680        690        700        710        720 
SGVSRIHADR DRAFSEVEKI KEEMERTQAT LGKSQLQHEK LQNSLDKAQN EVDHLQDKLD 

       730        740        750        760        770        780 
KACTENRRLV LEKEKLTYDY DNLQSQLDKA LGQAARMQKE RETLSLDTDR IREKLEKTQV 

       790        800        810        820        830        840 
QLGRIQKERD QFSDELETLK ERSESAQTLL MKAARDREAM QTDLEVLKER YEKSHAIQQK 

       850        860        870        880        890        900 
LQMERDDAVT EVEILKEKLD KALYASQKLI DEKDTSNKEF EKMLEKYDRA QNEIYRLQSR 

       910        920        930        940        950        960 
CDTAEADRAR LEVEAERSGL AASKAREDLR KLQDESTRLQ EACDRAALQL SRAKECEDNA 

       970        980        990       1000       1010       1020 
RSELEHSRDR FDKLQTDIRR AQGEKEHFQS ELERVTYELE RAHAAQTKAS ASVEAAKEEA 

      1030       1040       1050       1060       1070       1080 
AHYAVELEKM RDRYEKSQVE LRKLQDTDTF GRETRRLKEE NERLREKLDK TLMELETIRG 

      1090       1100       1110       1120       1130       1140 
KSQYESESFE KYKDKYEKIE MEVQNMESKL HETSLQLELS KGEVAKMLAN QEKQRSELER 

      1150       1160       1170       1180       1190       1200 
AHIEREKARD KHEKLLKEVD RLRLQQSSVS PGDPVRASTS SSSALSAGER QEIDRLRDRL 

      1210       1220       1230       1240       1250       1260 
EKALQSRDAT ELEAGRLAKE LEKAQMHLAK QQENTESTRI EFERMGAELG RLHDRLEKAE 

      1270       1280       1290       1300       1310       1320 
AEREALRQAN RSGGAGAAPH PQLEKHVQKL ESDVKQLAME REQLVLQLEK SQEILMNFQK 

      1330       1340       1350       1360       1370       1380 
ELQNAEAELQ KTREENRKLR NGHQVPPVAA PPAGPSPAEF QAMQKEIQTL QQKLQESERA 

      1390       1400       1410       1420       1430       1440 
LQAAGPQQAQ AAAAAGASRE EIEQWRKVIE QEKSRADMAD KAAQEMHKRI QLMDQHIKDQ 

      1450       1460       1470       1480       1490       1500 
HAQMQKMQQQ MQQQQQAAQQ AVQQAAQQQQ SAAGAGGADP KELEKVRGEL QAACTERDRF 

      1510       1520       1530       1540       1550       1560 
QQQLELLVTE LEKSKMSNQE QAKQLQTAQQ QVQQLQQQVQ QLQQQMQQLQ QAASAGAGAT 

      1570       1580       1590       1600       1610       1620 
DVQRQQLEQQ QKQLEEVRKQ IDNQAKATEG ERKIIDEQRK QIDAKRKDIE EKEKKMAEFD 

      1630       1640       1650       1660       1670       1680 
VQLRKRKEQM DQLEKSLQTQ GGGAAAAGEL NKKLMDTQRQ LEACVKELQN TKEEHKKAAT 

      1690       1700       1710       1720       1730       1740 
ETERLLQLVQ MSQEEQNAKE KTIMDLQQAL KIAQAKVKQA QTQQQQQQDA GPAGFLKSFF

References

[1]

"Bruchpilot, a protein with homology to ELKS/CAST, is required for structural integrity and function of synaptic active zones in Drosophila."
Wagh D.A., Rasse T.M., Asan E., Hofbauer A., Schwenkert I., Durrbeck H., Buchner S., Dabauvalle M.C., Schmidt M., Qin G., Wichmann C., Kittel R., Sigrist S.J., Buchner E.
Neuron 49:833-844(2006) [PubMed: 16543132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Nervous tissue EMBL CAH61079.2.

Cross-references

Sequence databases
	AJ849544 mRNA. Translation: CAH61079.2.
3D structure databases
ModBase	Search...
Organism-specific databases
FlyBase	FBgn0259246. brp.
Phylogenomic databases
HOGENOM	Q25B55.
Gene expression databases
ArrayExpress	Q25B55.

Entry information

Entry name

Q25B55_DROME

Accession

Primary (citable) accession number: Q25B55

Entry history

Integrated into UniProtKB/TrEMBL:	April 18, 2006
Last sequence update:	April 18, 2006
Last modified:	November 4, 2008
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information