Reviewed,
UniProtKB/Swiss-Prot P0A4Y3 (Y1353_MYCBO)
Last modified
November 4, 2008.
Version 29.
History...
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90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Uncharacterized protein Mb1353c | ||
| Gene names |
| ||
| Organism | Mycobacterium bovis [Complete proteome] [HAMAP] | ||
| Taxonomic identifier | 1765 [NCBI] | ||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex |
Protein attributes
| Sequence length | 535 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Subcellular location | Cell membrane; Multi-pass membrane proteinPotential. |
| Sequence similarities | Belongs to the adenylyl cyclase class-3 family. Contains 1 guanylate cyclase domain. Contains 1 HAMP domain. |
Ontologies
Keywords | |
|---|---|
| Cellular component | Cell membrane Membrane |
| Domain | Transmembrane |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membraneInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 535 | 535 | Uncharacterized protein Mb1353c | PRO_0000195753 | |||||
Regions | |||||||||
| Transmembrane | 63 – 83 | 21 | Potential | ||||||
| Transmembrane | 90 – 110 | 21 | Potential | ||||||
| Transmembrane | 143 – 163 | 21 | Potential | ||||||
| Transmembrane | 168 – 188 | 21 | Potential | ||||||
| Transmembrane | 226 – 246 | 21 | Potential | ||||||
| Transmembrane | 258 – 278 | 21 | Potential | ||||||
| Domain | 279 – 330 | 52 | HAMP | ||||||
| Domain | 362 – 486 | 125 | Guanylate cyclase | ||||||
Sequences
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References
| [1] | "The complete genome sequence of Mycobacterium bovis." Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M., Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B., Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J. Hewinson R.G.Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003) [PubMed: 12788972] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-935 / AF2122/97. |
Cross-references
Sequence databases | |
|---|---|
| BX248338 Genomic DNA. Translation: CAD94214.1. | |
| RefSeq | NP_855007.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1090645. |
| GenomeReviews | Gene locus Mb1353c in contig BX248333_GR. |
| KEGG | mbo:Mb1353c. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | P0A4Y3. |
Family and domain databases | |
| InterPro | IPR001054. A/G_cyclase. IPR003660. Sig_transdc_His_kinase_HAMP. [Graphical view] |
| Gene3D | G3DSA:3.30.70.1230. A/G_cyclase. 1 hit. |
| Pfam | PF00211. Guanylate_cyc. 1 hit. PF00672. HAMP. 1 hit. [Graphical view] |
| SMART | SM00044. CYCc. 1 hit. SM00304. HAMP. 1 hit. [Graphical view] |
| PROSITE | PS50125. GUANYLATE_CYCLASE_2. 1 hit. PS50885. HAMP. 1 hit. [Graphical view] |
| BLOCKS | Search... |
| ProtoNet | Search... |
Entry information
| Entry name | Y1353_MYCBO | ||||||||
| Accession | Primary (citable) accession number: P0A4Y3 Secondary accession number(s): Q10632 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| UniProtKB secondary accession numbers Index of UniProtKB secondary accession numbers |
| SIMILARITY comments Index of protein domains and families |

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