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Reviewed, UniProtKB/Swiss-Prot O60739 (EIF1B_HUMAN)

Last modified November 25, 2008. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Eukaryotic translation initiation factor 1b
      Short name=eIF1b
Alternative name(s):
    Protein translation factor SUI1 homolog GC20
Gene names
Name: EIF1B
OrganismHomo sapiens (Human)
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length113 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Function

Probably involved in translation.

Sequence similarities

Belongs to the SUI1 family.

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Ontologies

Keywords

   Biological processProtein biosynthesis

Gene Ontology (GO)

   Biological processregulation of translational initiation

Non-traceable author statement. Source: UniProtKB

   Molecular functionprotein binding

Inferred from physical interaction. Source: IntAct

translation initiation factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 113113Eukaryotic translation initiation factor 1b
PRO_0000130558

Experimental info

Sequence conflict271T → L in AAC17112. Ref.1
Sequence conflict411R → G in AAC17112. Ref.1

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Sequences

Sequence LengthMass (Da)Tools
O60739-1 [UniParc].

Last modified December 1, 2000. Version 2.
Checksum: 4522A8B692654FE1

FASTA11312,824
        10         20         30         40         50         60 
MSTIQNLQSF DPFADATKGD DLLPAGTEDY IHIRIQQRNG RKTLTTVQGI ADDYDKKKLV 

        70         80         90        100        110 
KAFKKKFACN GTVIEHPEYG EVIQLQGDQR KNICQFLLEV GIVKEEQLKV HGF

« Hide

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References

« Hide 'large scale' references
[1]"Human dendritic cell SUI1 homolog gene."
Zhao Z., Huang X., Li N., Zhu X., Cao X.
Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Blood.
[2]"Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning."
Hu R.-M., Han Z.-G., Song H.-D., Peng Y.-D., Huang Q.-H., Ren S.-X., Gu Y.-J., Huang C.-H., Li Y.-B., Jiang C.-L., Fu G., Zhang Q.-H., Gu B.-W., Dai M., Mao Y.-F., Gao G.-F., Rong R., Ye M. expand/collapse author list , Zhou J., Xu S.-H., Gu J., Shi J.-X., Jin W.-R., Zhang C.-K., Wu T.-M., Huang G.-Y., Chen Z., Chen M.-D., Chen J.-L.
Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000) [PubMed: 10931946] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Pituitary.
[3]"Homo sapiens translational factor eIF-1."
Kim D.-G., You K.-R.
Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Liver.
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Kidney.

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Cross-references

Sequence databases

AF064607 mRNA. Translation: AAC17112.1.
AF077052 mRNA. Translation: AAD27785.1.
AF263452 mRNA. Translation: AAF79182.1.
BC006996 mRNA. Translation: AAH06996.1.
RefSeqNP_005866.1.
UniGeneHs.315230

3D structure databases

HSSPHSSP built from PDB template 2IF1 based on UniProtKB P41567.
SMRO60739. Positions 1-113.
ModBaseSearch...

Protein-protein interaction databases

IntActO60739.

Genome annotation databases

EnsemblENSG00000114784. Homo sapiens. [Contig view]
GeneID10289.
KEGGhsa:10289.

Organism-specific databases

HGNCHGNC:30792. EIF1B.
GenAtlasSearch...
GeneCardsSearch...

Phylogenomic databases

HOGENOMO60739.
HOVERGENO60739.

Gene expression databases

ArrayExpressO60739.
CleanExHS_EIF1B.
GermOnlineENSG00000114784. Homo sapiens.

Family and domain databases

InterProIPR005874. SUI1_euk.
IPR001950. TIF_SUI1.
[Graphical view]
PfamPF01253. SUI1. 1 hit.
[Graphical view]
PIRSFPIRSF004499. SUI1_euk. 1 hit.
TIGRFAMsTIGR01160. SUI1_MOF2. 1 hit.
PROSITEPS50296. SUI1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

LinkHubO60739.
NextBio38988.

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Entry information

Entry nameEIF1B_HUMAN
AccessionPrimary (citable) accession number: O60739
Secondary accession number(s): Q9UQF8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: December 1, 2000
Last modified: November 25, 2008
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

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Relevant documents

Human chromosome 3

Human chromosome 3: entries, gene names and cross-references to MIM

Translation initiation factors

List of translation initiation factor entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents