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Unreviewed, UniProtKB/TrEMBL A1ZAW0 (A1ZAW0_DROME)

Last modified July 22, 2008. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    CG6493-PA EMBL AAF57830.2
    EC=3.6.1.3
Gene names
Name: Dcr-2 FlyBase FBgn0034246
ORF Names: Dmel_CG6493 EMBL AAF57830.2
OrganismDrosophila melanogaster (Fruit fly) [Complete proteome]
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

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Protein attributes

Sequence length1722 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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Sequences

Sequence LengthMass (Da)Tools
A1ZAW0-1 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 73755021033C399A

FASTA1,722197,765
        10         20         30         40         50         60 
MEDVEIKPRG YQLRLVDHLT KSNGIVYLPT GSGKTFVAIL VLKRFSQDFD KPIESGGKRA 

        70         80         90        100        110        120 
LFMCNTVELA RQQAMAVRRC TNFKVGFYVG EQGVDDWTRG MWSDEIKKNQ VLVGTAQVFL 

       130        140        150        160        170        180 
DMVTQTYVAL SSLSVVIIDE CHHGTGHHPF REFMRLFTIA NQTKLPRVVG LTGVLIKGNE 

       190        200        210        220        230        240 
ITNVATKLKE LEITYRGNII TVSDTKEMEN VMLYATKPTE VMVSFPHQEQ VLTVTRLISA 

       250        260        270        280        290        300 
EIEKFYVSLD LMNIGVQPIR RSKSLQCLRD PSKKSFVKQL FNDFLYQMKE YGIYAASIAI 

       310        320        330        340        350        360 
ISLIVEFDIK RRQAETLSVK LMHRTALTLC EKIRHLLVQK LQDMTYDDDD DNVNTEEVIM 

       370        380        390        400        410        420 
NFSTPKVQRF LMSLKVSFAD KDPKDICCLV FVERRYTCKC IYGLLLNYIQ STPELRNVLT 

       430        440        450        460        470        480 
PQFMVGRNNI SPDFESVLER KWQKSAIQQF RDGNANLMIC SSVLEEGIDV QACNHVFILD 

       490        500        510        520        530        540 
PVKTFNMYVQ SKGRARTTEA KFVLFTADKE REKTIQQIYQ YRKAHNDIAE YLKDRVLEKT 

       550        560        570        580        590        600 
EPELYEIKGH FQDDIDPFTN ENGAVLLPNN ALAILHRYCQ TIPTDAFGFV IPWFHVLQED 

       610        620        630        640        650        660 
ERDRIFGVSA KGKHVISINM PVNCMLRDTI YSDPMDNVKT AKISAAFKAC KVLYSLGELN 

       670        680        690        700        710        720 
ERFVPKTLKE RVASIADVHF EHWNKYGDSV TATVNKADKS KDRTYKTECP LEFYDALPRV 

       730        740        750        760        770        780 
GEICYAYEIF LEPQFESCEY TEHMYLNLQT PRNYAILLRN KLPRLAEMPL FSNQGKLHVR 

       790        800        810        820        830        840 
VANAPLEVII QNSEQLELLH QFHGMVFRDI LKIWHPFFVL DRRSKENSYL VVPLILGAGE 

       850        860        870        880        890        900 
QKCFDWELMT NFRRLPQSHG SNVQQREQQP APRPEDFEGK IVTQWYANYD KPMLVTKVHR 

       910        920        930        940        950        960 
ELTPLSYMEK NQQDKTYYEF TMSKYGNRIG DVVHKDKFMI EVRDLTEQLT FYVHNRGKFN 

       970        980        990       1000       1010       1020 
AKSKAKMKVI LIPELCFNFN FPGDLWLKLI FLPSILNRMY FLLHAEALRK RFNTYLNLHL 

      1030       1040       1050       1060       1070       1080 
LPFNGTDYMP RPLEIDYSLK RNVDPLGNVI PTEDIEEPKS LLEPMPTKSI EASVANLEIT 

      1090       1100       1110       1120       1130       1140 
EFENPWQKYM EPVDLSRNLL STYPVELDYY YHFSVGNVCE MNEMDFEDKE YWAKNQFHMP 

      1150       1160       1170       1180       1190       1200 
TGNIYGNRTP AKTNANVPAL MPSKPTVRGK VKPLLILQKT VSKEHITPAE QGEFLAAITA 

      1210       1220       1230       1240       1250       1260 
SSAADVFDME RLEILGDSFL KLSATLYLAS KYSDWNEGTL TEVKSKLVSN RNLLFCLIDA 

      1270       1280       1290       1300       1310       1320 
DIPKTLNTIQ FTPRYTWLPP GISLPHNVLA LWRENPEFAK IIGPHNLRDL ALGDEESLVK 

      1330       1340       1350       1360       1370       1380 
GNCSDINYNR FVEGCRANGQ SFYAGADFSS EVNFCVGLVT IPNKVIADTL EALLGVIVKN 

      1390       1400       1410       1420       1430       1440 
YGLQHAFKML EYFKICRADI DKPLTQLLNL ELGGKKMRAN VNTTEIDGFL INHYYLEKNL 

      1450       1460       1470       1480       1490       1500 
GYTFKDRRYL LQALTHPSYP TNRITGSYQE LEFIGDAILD FLISAYIFEN NTKMNPGALT 

      1510       1520       1530       1540       1550       1560 
DLRSALVNNT TLACICVRHR LHFFILAENA KLSEIISKFV NFQESQGHRV TNYVRILLEE 

      1570       1580       1590       1600       1610       1620 
ADVQPTPLDL DDELDMTELP HANKCISQEA EKGVPPKGEF NMSTNVDVPK ALGDVLEALI 

      1630       1640       1650       1660       1670       1680 
AAVYLDCRDL QRTWEVIFNL FEPELQEFTR KVPINHIRQL VEHKHAKPVF SSPIVEGETV 

      1690       1700       1710       1720 
MVSCQFTCME KTIKVYGFGS NKDQAKLSAA KHALQQLSKC DA

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References

[1]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"Phosphoproteome analysis of Drosophila melanogaster embryos."
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.
J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
+Additional computationally mapped references.

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Cross-references

Sequence databases

AE013599 Genomic DNA. Translation: AAF57830.2.
RefSeqNP_523778.2.
UniGeneDm.7764

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID36993.
KEGGdme:Dmel_CG6493.

Organism-specific databases

FlyBaseFBgn0034246. Dcr-2.

Family and domain databases

InterProIPR014001. DEAD-like_N.
IPR001650. DNA/RNA_helicase_C.
IPR011545. DNA/RNA_helicase_DEAD/DEAH_N.
IPR001159. Ds_RNA_bd.
IPR005034. DUF283.
IPR014021. Helicase_SF1/SF2_ATP-bd.
IPR003100. PAZ.
IPR000999. RNase_III.
[Graphical view]
Gene3DG3DSA:1.10.1520.10. RNase_III. 2 hits.
PfamPF00270. DEAD. 1 hit.
PF00035. dsrm. 1 hit.
PF03368. DUF283. 1 hit.
PF00271. Helicase_C. 1 hit.
PF02170. PAZ. 1 hit.
PF00636. Ribonuclease_3. 2 hits.
[Graphical view]
SMARTSM00487. DEXDc. 1 hit.
SM00358. DSRM. 1 hit.
SM00490. HELICc. 1 hit.
SM00535. RIBOc. 2 hits.
[Graphical view]
PROSITEPS50137. DS_RBD. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS50821. PAZ. 1 hit.
PS50142. RNASE_3_2. 2 hits.
[Graphical view]
ProDomA1ZAW0.
[Graphical view] [Entries sharing at least one domain]

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Entry information

Entry nameA1ZAW0_DROME
AccessionPrimary (citable) accession number: A1ZAW0
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: July 22, 2008
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information