UniProt is updated every four weeks (see FAQ on
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You can download small data sets and subsets directly from
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If you are located in Europe, the Middle East or Africa, you
may want to download data from our mirror site in the
or in Switzerland instead.
Here are some direct links to frequently downloaded files:
UniProtKBParent Directory (FTP)
UniRefParent Directory (FTP)
UniParcParent Directory (FTP)
UniMESParent Directory (FTP)
UniProt RDF distributionParent Directory (FTP)