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UniProt is updated every four weeks (see FAQ on how to be notified automatically of updates). You can download small data sets and subsets directly from this website by following the download link on any search result page. For downloading complete data sets we recommend using ftp.uniprot.org. If you are located in Europe, the Middle East or Africa, you may want to download data from our mirror site in the United Kingdom or in Switzerland instead.

See also: Downloaded data seems incomplete or corrupted - how can I get help with download problems?

Here are the main sections of our FTP site, with links to README files and help pages and some frequently downloaded files:

UniProtKB

Parent directory
Reviewed (Swiss-Prot) / FAQxml | fasta | text
Unreviewed (TrEMBL) / FAQxml | fasta | text
Isoform sequences / FAQfasta
Taxonomic divisions / README
Reference proteomes / README
ID mapping / README
Proteomics mapping / README
Variants / README
Documents
XML schema


UniRef

Parent directory
UniRef100 / READMExml | fasta
UniRef90 / READMExml | fasta
UniRef50 / READMExml | fasta
XML schema


UniParc

Parent directory / README
UniParc (Sequence Archive) / Helpxml | fasta
XML schema


UniProt RDF distribution

Parent directory / README
OWL schema


UniProt information

Releases notes
Previous releases