scorpktx.txt
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UniProt - Swiss-Prot Protein Knowledgebase
SIB Swiss Institute of Bioinformatics; Geneva, Switzerland
European Bioinformatics Institute (EBI); Hinxton, United Kingdom
Protein Information Resource (PIR); Washington DC, USA
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Description: Scorpion potassium channel toxins: nomenclature and list of
entries
Name: scorpktx.txt
Release: 2013_06 of 29-May-2013
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This document lists potassium channel-specific scorpion toxins alpha-,
gamma- and kappa-KTx, according to the nomenclature system originally
described by Tytgat et al [1] in 1999 and extended in de la Vega et al
[2]. Beta-KTx listed here are divided into the three classes proposed
by Zhu et al [3]. For a detailed description of the animal toxin
annotation program in UniProtKB/Swiss-Prot, see [4]. We would like to
thank Dr. Ricardo C. Rodriguez de la Vega and Prof. Lourival D. Possani
for their help in establishing this list.
[1] [Pubmed: 10542442]
Tytgat J., Chandy K.G., Garcia M.L., Gutman G.A.,
Martin-Eauclaire M.F., van der Walt J.J., Possani L.D.
A unified nomenclature for short-chain peptides isolated from
scorpion venoms: alpha-KTx molecular subfamilies.
Trends Pharmacol. Sci. 20:444-447(1999).
[2] [Pubmed: 15208019] [Article from publisher]
Rodriguez de la Vega R.C., Possani L.D.;
Current views on scorpion toxins specific for K+-channels.
Toxicon 43:865-875(2004).
[3] [Pubmed: 20045493] [Article from publisher]
Zhu S., Gao B., Aumelas A., Del Carmen Rodriguez M., Lanz-Mendoza H.,
Peigneur S., Diego-Garcia E., Martin-Eauclaire M.-F., Tytgat J.,
Possani L.D.;
Biochim. Biophys. Acta 1804:872-883(2010).
[4] [Pubmed: 15683867] [Article from publisher]
Jungo F., Bairoch A.;
Tox-Prot, the toxin protein annotation program of the Swiss-Prot
protein knowledgebase.
Toxicon 45:293-301(2005).
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Swiss Entry name Systematic Other names
-Prot name
AC
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P13487 KAX11_LEIQH alpha-KTx 1.1 Charybdotoxin, ChTX, ChTX-Lq1, ChTx-a
P45628 KAX12_LEIQH alpha-KTx 1.2 Charybdotoxin-2, ChTX-Lq2, Toxin 18-2, Lqh 18-2, ChTx-d
P24663 KAX13_MESTA alpha-KTx 1.3 Iberiotoxin, IbTx
P0C167 KAX14_CENLM alpha-KTx 1.4 Limbatotoxin, LbTx, Limbatustoxin
Q9NII6 KAX15_MESMA alpha-KTx 1.5 Neurotoxin TX1, BmTX1
Q9NII5 KAX16_MESMA alpha-KTx 1.6 Neurotoxin TX2, BmTX2
P45660 KAX17_LEIQH alpha-KTx 1.7 Toxin 15-1, Lqh 15-1
alpha-KTx 1.8 [Corresponds to P0C173 reclassified as alpha-KTx 16.1]
P59848 KAX19_CENLM alpha-KTx 1.9 Hongotoxin-2, HgTX2
P83112 KAX1A_PARTR alpha-KTx 1.10 Parabutoxin-3, PBTx3
P0C182 KAX1B_CENNO alpha-KTx 1.11 Slotoxin, SloTx
P59943 KAX1C_LEIQH alpha-KTx 1.12 Charybdotoxin b, ChTx-b
P59944 KAX1D_LEIQH alpha-KTx 1.13 Charybdotoxin c, ChTx-c
H2ETQ6 KAX1E_MESMA alpha-KTx 1.14 Kcug1
H2ER23 KAX1F_MESMA alpha-KTx 1.15 Kcug2
P08815 KAX21_CENNO alpha-KTx 2.1 Noxiustoxin, NTx, Toxin II.11
P40755 KAX22_CENMA alpha-KTx 2.2 Margatoxin, MgTX
P45629 KAX23_CENLL alpha-KTx 2.3 Toxin-1, Toxin I, Toxin II.10.9.1, CllTx1
Q9TXD1 KAX24_CENNO alpha-KTx 2.4 Noxiustoxin-2, NTx2, NTx-2
P59847 KAX25_CENLM alpha-KTx 2.5 Hongotoxin-1, HgTX1
P59849 KAX26_CENLM alpha-KTx 2.6 Hongotoxin-3, HgTX3
P45630 KAX27_CENLL alpha-KTx 2.7 Toxin II, Toxin II.10.9.2, CllTx2
P0C161 KAX28_CENEL alpha-KTx 2.8 Toxin Ce1
P0C162 KAX29_CENEL alpha-KTx 2.9 Toxin Ce2
P0C163 KAX2A_CENEL alpha-KTx 2.10 Toxin Ce3
P0C164 KAX2B_CENEL alpha-KTx 2.11 Toxin Ce4
P0C165 KAX2C_CENEL alpha-KTx 2.12 Toxin Ce5
P85529 KAX2D_CENSU alpha-KTx 2.13 Toxin Css20
P24662 KAX31_ANDMA alpha-KTx 3.1 Kaliotoxin-1, KTX-1
P46111 KAX32_LEIQH alpha-KTx 3.2 Agitoxin-2, AGTX-2, AgTx2
P46112 KAX33_LEIQH alpha-KTx 3.3 Agitoxin-3, AGTX-3, AgTx3
P46110 KAX34_LEIQH alpha-KTx 3.4 Agitoxin-1, AGTX-1, AgTx1, Leiurotoxin-2, Leiurotoxin II, LeTx II
P45696 KAX35_ANDAU alpha-KTx 3.5 Kaliotoxin-2, KTX-2
Q9NII7 KAX36_MESMA alpha-KTx 3.6 Kaliotoxin, BmKTX
P55896 KAX37_ORTSC alpha-KTx 3.7 Toxin OsK1, OsK-1
P59886 KAX38_BUTSI alpha-KTx 3.8 Charybdotoxin-like peptide Bs 6, Bs6
P59290 KAX39_BUTOC alpha-KTx 3.9 Kaliotoxin-3, KTX-3
P0C908 KAX3A_BUTOS alpha-KTx 3.10 BoiTx1
P0C909 KAX3B_ODODO alpha-KTx 3.11 OdK2
P0C8R1 KAX3C_ANDAM alpha-KTx 3.12 Kaliotoxin analog, Aam-KTX
P46114 KAX41_TITSE alpha-KTx 4.1 Tityustoxin K-alpha, TsTX-K-alpha, TSK4, Toxin II-9
P56219 KAX42_TITSE alpha-KTx 4.2 Neurotoxin Ts-kappa, TsKapa, TsK
P59925 KAX43_TITDI alpha-KTx 4.3 Toxin TdK1
P60210 KAX44_TITOB alpha-KTx 4.4 Toxin Tc30
Q5G8B6 KAX45_TITCO alpha-KTx 4.5
P0CB56 KAX46_TITST alpha-KTx 4.6 Tst23
P16341 KAX51_LEIQH alpha-KTx 5.1 Leiurotoxin-1, Leiurotoxin I, LeTx I, Scyllatoxin, ScyTx
P31719 KAX52_ANDMA alpha-KTx 5.2 Leiurotoxin I-like toxin P05, AmP05
Q9TVX3 KAX53_MESMA alpha-KTx 5.3 Neurotoxin BmP05, Potassium ion channel blocker P05
P59869 KAX54_MESTA alpha-KTx 5.4 Tamapin
P59870 KAX55_MESTA alpha-KTx 5.5 Tamapin-2
Q10726 KAX61_PANIM alpha-KTx 6.1 Potassium channel-blocking toxin 1, Pi1, Pi-1, PiTX-K-gamma
P80719 KAX62_SCOMA alpha-KTx 6.2 Maurotoxin, MTX
P59867 KAX63_HETSP alpha-KTx 6.3 Neurotoxin HsTX1
P58498 KAX64_PANIM alpha-KTx 6.4 Potassium channel-blocking toxin 4, Pi4, Pi-4
P58490 KAX65_PANIM alpha-KTx 6.5 Pi7, Pi-7, Toxin-7
Q6XLL9 KAX66_OPICA alpha-KTx 6.6 OcKTx1
Q6XLL8 KAX67_OPICA alpha-KTx 6.7 OcKTx2
Q6XLL7 KAX68_OPICA alpha-KTx 6.8 OcKTx3
Q6XLL6 KAX69_OPICA alpha-KTx 6.9 OcKTx4
Q6XLL5 KAX6A_OPICA alpha-KTx 6.10 OcKTx5
P0C194 KAX6B_OPIMA alpha-KTx 6.11 Male-specific potassium channel inhibitor IsTX
P0C166 KAX6C_ANUPH alpha-KTx 6.12 Anuroctoxin
P84094 KAX6D_HETSP alpha-KTx 6.13 Spinoxin
P84864 KAX6E_HADGE alpha-KTx 6.14 HgeTx1
P85528 KAX6F_HEMLE alpha-KTx 6.15 Hemitoxin
C5J896 KAX6G_OPICY alpha-KTx 6.16
P55927 KAX71_PANIM alpha-KTx 7.1 Toxin PiTX-K-alpha, Pandinotoxin-alpha, Potassium channel-blocking toxin 2, Pi2, Pi-2
P55928 KAX72_PANIM alpha-KTx 7.2 Toxin PiTX-K-beta, Pandinotoxin-beta, Potassium channel-blocking toxin 3, Pi3, Pi-3
P56215 KAX81_ANDMA alpha-KTx 8.1 Neurotoxin P01, AmP01
Q9U8D2 KAX82_MESMA alpha-KTx 8.2 Neurotoxin BmP01, Potassium ion channel blocker P01
P80670 KAX83_LEIQH alpha-KTx 8.3 Toxin GaTx2, Gating modifier of anion channels 2, Leiuropeptide II, LpII, Leiuropeptide-2
P80671 KAX84_LEIQH alpha-KTx 8.4 Leiuropeptide-3, Leiuropeptide III, LpIII
P0CC12 KAX85_ODODO alpha-KTx 8.5 OdK1
Q9NJP7 KAX91_MESMA alpha-KTx 9.1 Neurotoxin BmP02, Potassium ion channel blocker P02, Toxin Kk6, BmKK6
Q9U8D1 KAX92_MESMA alpha-KTx 9.2 Neurotoxin BmP03, Potassium ion channel blocker P03
P80669 KAX93_LEIQH alpha-KTx 9.3 Leiuropeptide-1, Leiuropeptide I, LpI
P60209 KAX94_MESTA alpha-KTx 9.4 Toxin BTK-2, Bt BTK-2
P84744 KAX95_BUTOC alpha-KTx 9.5 Neurotoxin Kbot1
O46028 KA101_CENNO alpha-KTx 10.1 Cobatoxin-1, CoTx1, gtIX
P58504 KA102_CENNO alpha-KTx 10.2 Cobatoxin-2, CoTx2
P60164 KA111_PARVI alpha-KTx 11.1 Parabutoxin-1, PBTx1
P60165 KA112_PARVI alpha-KTx 11.2 Parabutoxin-2, PBTx2
Q6WGI9 KA113_PARGR alpha-KTx 11.3 Parabutoxin-10, PBTx10
P59936 KA121_TITSE alpha-KTx 12.1 Butantoxin, BuTX, TsTX-IV
P0C168 KA122_TITTR alpha-KTx 12.2 Butantoxin, BuTX, TtBut
P0C185 KA123_TITCO alpha-KTx 12.3 Butantoxin-like peptide, Tco30
P0C8L1 KA124_TITST alpha-KTx 12.4 Butantoxin, BuTX, TstBut
P0CH12 KA125_LYCMC alpha-KTx 12.5 Neurotoxin KTx10
P0CI47 KA126_LYCMC alpha-KTx 12.6
P0CI48 KA127_LYCMC alpha-KTx 12.7
P83243 KA131_TITOB alpha-KTx 13.1 Toxin Tc1
P83244 KA132_ORTSC alpha-KTx 13.2 Toxin OsK2, OsK-2
P84630 KA133_TITPA alpha-KTx 13.3 Toxin Tpa1
P0C8L2 KA134_TITST alpha-KTx 13.4 Toxin Tst-17
Q967F9 KA141_MESMA alpha-KTx 14.1 Toxin Kk1, BmKK1
Q95NK7 KA142_MESMA alpha-KTx 14.2 Toxin Kk2, BmKK2, BmTXKS3, Neurotoxin BmP07, Potassium ion channel blocker P07, KK1
Q9BJX2 KA143_MESMA alpha-KTx 14.3 Toxin Kk3, BmKK3, Neurotoxin SKTx2
Q9BKB4 KA144_MESMA alpha-KTx 14.4 Neurotoxin SKTx1, BmSKTx1
P60233 KA151_ANDAU alpha-KTx 15.1 Peptide Aa1
Q8I0L5 KA152_MESMA alpha-KTx 15.2 Toxin BmTX3, Neurotoxin TX3, BmTX3A
P60208 KA153_ANDMA alpha-KTx 15.3 Toxin AmmTX3
Q867F4 KA154_ANDAU alpha-KTx 15.4 Toxin AaTX1, Toxin Aa1
Q86SD8 KA155_ANDAU alpha-KTx 15.5 Toxin AaTX2
P84777 KA156_TITDI alpha-KTx 15.6 Discrepin
Q5K0E0 KA157_ANDAM alpha-KTx 15.7 Neurotoxin AamTX
Q86BX0 KA158_MESMA alpha-KTx 15.8 Neurotoxin Kk4, BmKKx1
D9U2A8 KA159_LYCMC alpha-KTx 15.9 Neurotoxin KTx9
P0C173 KA161_MESTA alpha-KTx 16.1 Tamulotoxin, TmTX
Q9NBG9 KA162_MESMA alpha-KTx 16.2 Martentoxin, BmK 622, BmTx3B, [Contains: Martentoxin-1 Martentoxin I,
Q8MQL0 KA163_MESMA alpha-KTx 16.3 Charybdotoxin-like toxin 1, Kchtx1, KTX1
Q95NJ8 KA171_MESMA alpha-KTx 17.1 Toxin Kk4, BmKK4, Toxin TXKs4
P0CI46 KA172_LYCMC alpha-KTx 17.2
P60211 KA181_TITOB alpha-KTx 18.1 Toxin Tc32
P0C1X5 KA182_TITDI alpha-KTx 18.2 Toxin TdK2
P0C1X6 KA183_TITDI alpha-KTx 18.3 Toxin TdK3
P83407 KA191_MESMA alpha-KTx 19.1 Neurotoxin BmBKTx1, BmK37
P0C183 KA201_TITTR alpha-KTx 20.1 Toxin Tt28
P86270 KA211_TITSE alpha-KTx 21.1 Tityustoxin-15, TS15
Q8MUB1 KA221_MESMA alpha-KTx 22.1 Toxin Kcugx, Neurotoxin BmK38
P0DJ31 KA231_VAEMS alpha-KTx 23.1 Toxin Vm24, Toxin alpha-KTx 21.1
P0DJ32 KA232_VAEMS alpha-KTx 23.2 Toxin Vm23, Toxin alpha-KTx 21.2
A7KJJ7 KA261_MESMA alpha-KTx 26.1 Neurotoxin BmK86
D9U2B2 KA262_LYCMC alpha-KTx 26.2
class 1 subfamily:
P69939 KBX1_ANDAU AaTXK-beta, AaTXKbeta, beta-KTx 2
B8XH40 KBX1_BUTOS BuTXK-beta, BuTXKbeta, Tx690
Q9N661 KBX1_MESMA BmTXK-beta-2, BmTX K-beta2, BmTXKbeta2, BmTX K beta2', beta-KTx 4
Q5G8A6 KBX1_TITCO Tco-beta-KTx, TcobetaKTx, Tco 41.46-2, Tco 42.14
Q0GY44 KBX1_TITDI Tdi-beta-KTx, TdibetaKTx
P69940 KBX1_TITSE TsTXK-beta, Tityustoxin K-beta, TsTX-K beta, TsTX K beta, TsTXKbeta, TSK2, beta-KTx 1
P0C2F3 KBX1_TITST Tst-beta-KTx, TstbetaKTx
Q0GY46 KBX1_TITTR Ttr-beta-KTx, TtrbetaKTx
P0CI49 KBX11_LYCMC Neurotoxin beta-KTx 31.1
A9XE60 KBX11_MESEU MeuTXK-beta-1, MeuTXKbeta1
A9XE59 KBX12_MESEU MeuTXK-beta-2, MeuTXKbeta2
D9U2A7 KBX17_LYCMC Neurotoxin beta-KTx 7
class 2 subfamily:
Q0GY41 KBX2_HADGE Hge-beta-KTx, HgebetaKTx
P0CH57 KBX2_MESEU MeuTXKbeta3, BeL-5, BeL-69, Meucin-24, MeuTXKbeta3
Q9NJC6 KBX2_MESMA BmTXK-beta, BmTX K-beta, BmTXKbeta, BmKLK, beta-KTx 3
Q0GY42 KBX2_TITCO TcoKIK
Q0GY43 KIK2_TITDI TdiKIK, TdKIK;
P0C8W4 KBX2_TITST TstKMK, Toxin 5536
P86822 KBX2_TITSE Beta-Ktx 2
Q0GY45 KBX2_TITTR TtrKIK
P0CJ45 KBX21_LYCMC Neurotoxin beta-KTx 52.1
D9U2B1 KBX22_LYCMC Neurotoxin beta-KTx 12
P0CI42 KBX23_LYCMC Neurotoxin beta-KTx 14.3
C6ZH27 KBX27_LYCMC Neurotoxin beta-KTx 17
class 3 subfamily:
Q0GY40 KBX3_HADGE Hge-scorpine, Hg-scorpine-like 1, Hgscplike1, HgeScplp1, Hge36
P0C2F4 KBX3_HETLA Heteroscorpine-1, HS-1
C5J891 KBX3_OPICY Scorpine-like, OcyC7
P56972 KBX3_PANIM Scorpine, Scorpin, Panscorpine
P86121 KBX3L_OPICY Scorpine-like
Q5WR03 KBX31_OPICA Opiscorpine-1
P0C8W5 KBX32_HADGE Hg-scorpine-like 2, Hgscplike2, HgeScplp2
Q5WR01 KBX32_OPICA Opiscorpine-2
Q5WQZ7 KBX33_OPICA Opiscorpine-3
Q5WQZ9 KBX34_OPICA Opiscorpine-4
Q86QT3 KGX11_CENNO gamma-KTx 1.1 Ergtoxin, ErgTx, Ergtoxin-like protein 1, ErgTx1, CnErg1, CnErgTx1
Q86QV6 KGX12_CENEL gamma-KTx 1.2 Ergtoxin-like protein 1, ErgTx1, CeErg1, CeErgTx1
Q86QV3 KGX13_CENGR gamma-KTx 1.3 Ergtoxin-like protein 1, ErgTx1, CgErg1, CgErgTx1
Q86QU6 KGX14_CENSC gamma-KTx 1.4 Ergtoxin-like protein 1, ErgTx1, CsErg1, CsErgTx1
Q86QV0 KGX15_CENLL gamma-KTx 1.5 Ergtoxin-like protein 1, ErgTx1, CllErg1, CllErgTx1
Q86QU1 KGX16_CENEX gamma-KTx 1.6 Ergtoxin-like protein 1, ErgTx1, CexErg1, CexErgTx1
P0C892 KGX17_CENEL gamma-KTx 1.7 CeErg4
P0C893 KGX18_CENEL gamma-KTx 1.8 CeErg5
Q9BKB7 KGX21_MESEU gamma-KTx 2.1 Neurotoxin BeKm-1
P59938 KGX22_MESMA gamma-KTx 2.2 Neurotoxin Kk7, BmKK7, BmKKx2
P59939 KGX31_CENNO gamma-KTx 3.1 Ergtoxin-like protein 2, ErgTx2, CnErg2, CnErgTx2
Q86QV5 KGX32_CENEL gamma-KTx 3.2 Ergtoxin-like protein 2, ErgTx2, CeErg2, CeErgTx2
Q86QU5 KGX33_CENSC gamma-KTx 3.3 Ergtoxin-like protein 2, ErgTx2, CsErg2, CsErgTx2
Q86QV2 KGX34_CENGR gamma-KTx 3.4 Ergtoxin-like protein 2, ErgTx2, CgErg2, CgErgTx2
Q86QU9 KGX41_CENLL gamma-KTx 4.1 Ergtoxin-like protein 2, ErgTx2, CllErg2, CllErgTx2
Q86QV7 KGX42_CENNO gamma-KTx 4.2 Ergtoxin-like protein 5, ErgTx5, CnErg5, CnErgTx5
Q86QU0 KGX43_CENEX gamma-KTx 4.3 Ergtoxin-like protein 2, ErgTx2, CexErg2, CexErgTx2
Q86QT9 KGX44_CENEX gamma-KTx 4.4 Ergtoxin-like protein 3, ErgTx3, CexErg3, CexErgTx3
Q86QT8 KGX45_CENEX gamma-KTx 4.5 Ergtoxin-like protein 4, ErgTx4, CexErg4, CexErgTx4
Q86QU8 KGX46_CENLL gamma-KTx 4.6 Ergtoxin-like protein 3, ErgTx3, CllErg3, CllErgTx3
Q86QU7 KGX47_CENLL gamma-KTx 4.7 Ergtoxin-like protein 4, ErgTx4, CllErg4, CllErgTx4
Q86QV4 KGX48_CENEL gamma-KTx 4.8 Ergtoxin-like protein 3, ErgTx3, CeErg3, CeErgTx3
Q86QU4 KGX49_CENSC gamma-KTx 4.9 Ergtoxin-like protein 3, ErgTx3, CsErg3, CsErgTx3
Q86QU3 KGX4A_CENSC gamma-KTx 4.10 Ergtoxin-like protein 4, ErgTx4, CsErg4, CsErgTx4
Q86QV8 KGX4B_CENNO gamma-KTx 4.11 Ergtoxin-like protein 4, ErgTx4, CnErg4, CnErgTx4
P59940 KGX4C_CENSC gamma-KTx 4.12 Neurotoxin CsEKerg1
Q86QV9 KGX4D_CENNO gamma-KTx 4.13 Ergtoxin-like protein 3, ErgTx3, CnErg3, CnErgTx3
Q86QU2 KGX51_CENSC gamma-KTx 5.1 Ergtoxin-like protein 5, ErgTx5, CsErg5, CsErgTx5
Q86QV1 KGX52_CENGR gamma-KTx 5.2 Ergtoxin-like protein 3, ErgTx3, CgErg3, CgErgTx3
P82850 KKX11_HETFU kappa-KTx 1.1 Kappa-hefutoxin-1, Kappa-HfTx1
P82851 KKX12_HETFU kappa-KTx 1.2 Kappa-hefutoxin-2, Kappa-HfTx2
P83655 KKX13_HETSP kappa-KTx 1.3
P0DJ33 KKX14_HETPE kappa-KTx 1.4 HSP009C
P0C1Z3 KKX21_OPIMA kappa-KTx 2.1 Toxin OmTx1
P0C1Z3 KKX21_OPIMA kappa-KTx 2.2 Toxin OmTx2
P0C1Z4 KKX23_OPIMA kappa-KTx 2.3 Toxin OmTx3
P0C1Z3 KKX21_OPIMA kappa-KTx 2.4 Toxin OmTx4
P86110 KKX25_OPICY kappa-KTx 2.5 OcyC8, OcyKTx6
C5J893 KKX26_OPICY kappa-KTx 2.6 OcyC9
P0DJ34 KKX27_HETPE kappa-KTx 2.7 HSP053C.1
P0DJ35 KKX28_HETPE kappa-KTx 2.8 HSP053C.2
P0DJ36 KKX31_HETPE kappa-KTx 3.1 HSP040C.1
P0DJ37 KKX32_HETPE kappa-KTx 3.2 HSP040C.3
P0DJ38 KKX33_HETPE kappa-KTx 3.3 HSP040C.4
P0DJ39 KKX34_HETPE kappa-KTx 3.4 HSP040C.5
P0DJ40 KKX41_HETPE kappa-KTx 4.1 HSP040C.2
P0DJ41 KKX51_HETLA kappa-KTx 5.1 HelaTx1
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