restric.txt
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UniProt - Swiss-Prot Protein Knowledgebase
SIB Swiss Institute of Bioinformatics; Geneva, Switzerland
European Bioinformatics Institute (EBI); Hinxton, United Kingdom
Protein Information Resource (PIR); Washington DC, USA
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Description: Restriction enzymes and methylases: classification and list of
entries
Name: restric.txt
Release: 2013_06 of 29-May-2013
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Further informations about restriction enzymes and their associated
methylases is available from:
http://rebase.neb.com/
==============================
Type II enzymes and methylases
==============================
_________ _________________________ ____________________ ____ ____________________
Name Recognition site(s) Restriction Type Methylase(s)
of enzyme enzyme of
Entry name AC met. Entry name AC
_________ _________________________ ____________________ ____ ____________________
AbrI C^TCGAG T2A1_AZOBR (P26919) 6mA MTA1_AZOBR (P58284)
AccI GT^MKAC T2A1_ACICA (P24546) 6mA MTA1_ACICA (P25201)
AgeI A^CCGGT T2A1_RUEGE (Q9KHV6) 5mC MTA1_RUEGE (P94147)
AluI AG^CT N.A. 5mC MTA1_CELCE (P31974)
ApaLI G^TGCAC T2A1_ACEPA (O52703) 5mC MTA1_ACEPA (O52702)
AquI C^YCGRG N.A. 5mC MTAA_SYNP2 (P34882)
MTAB_SYNP2 (P34883)
AvaI C^YCGRG T2A1_NOSS1 (P0A457) 4mC MTA1_NOSS1 (P0A461)
AvaI C^YCGRG T2A1_ANAVA (P0A458) 4mC MTA1_ANAVA (P0A462)
BamHI G^GATCC T2BA_BACAM (P23940) 4mC MTB1_BACAM (P23941)
BamHII GGATCC N.A. 4mC MTB2_BACAM (P18051)
BanI G^GYRCC T2BA_BACAR (P19887) 5mC MTBA_BACAR (P19888)
BanIII AT^CGAT N.A. 6mA MTB3_BACAR (P22772)
BbvI GCAGC (13); GCTGC (-12) N.A. 5mC MTB1_BREBE (P34905)
BepI CG^CG N.A. 5mC MTB1_BREEP (P10283)
BglI GCCNNNN^NGGC T2B1_BACIU (O68557) 4mC MTB1_BACIU (O68556)
BglII A^GATCT T2B2_BACIU (Q45488) 4mC MTB2_BACIU (Q45489)
BseCI AT^CGAT N.A. 5mC MTC1_GEOSE (P43423)
BslI CCNNNNN^NNGG T2BLA_BACSQ (Q9LAI1) 4mC MTB1_BACSQ (Q9LAI2)
T2BLB_BACSQ (Q9LAI0)
BsoBI C^YCGRG T2B1_GEOSE (P70985) 4mC MTB1_GEOSE (P70986)
Bsp6I GC^NGC T2B6_BACSF (P43419) 5mC MTB6_BACSF (P43420)
BspRI GG^CC N.A. 5mC MTB1_LYSSH (P13906)
BstVI C^TCGAG T2V1_GEOSE (P43421) 6mA MTV1_GEOSE (P43422)
BsuBI CTGCAG T2BB_BACIU (P33562) 6mA MTBB_BACIU (P33563)
BsuFI C^CGG T2BF_BACIU (P25217) 5mC MTBF_BACIU (P17044)
BsuRI GG^CC T2BR_BACIU (P06529) 5mC MTBR_BACIU (P06530)
CeqI GAT^ATC T2C1_COREQ (P42827) 6mA MTC1_COREQ (P42828)
Cfr9I C^CCGGG T2C9_CITFR (Q60132) 4mC MTC9_CITFR (P14243)
Cfr10I R^CCGGY T2CX_CITFR (P56200) 5mC N.A.
CfrBI C^CWWGG T2C1_CITFR (Q04852) 4mC MTC1_CITFR (Q04845)
CviAII C^ATG T2C2_PBCV1 (P31117) 6mA MTC2_PBCV1 (P31118)
CviBI G^ANTC N.A. 6mA MTC1_PBCVC (Q01511)
CviJI RG^CY T2C1_PBCVI (P52283) 5mC MTC1_PBCVI (P36216)
CviRI TG^CA N.A. 6mA MTR1_PBCVX (P52284)
DdeI C^TNAG T2D1_DESNO (P05301) 5mC MTD1_DESNO (P05302)
DpnI GA^TC T2D1_STRPN (P0A459) ? N.A.
DpnII ^GATC T2D2_STREE (P09357) 6mA MTD21_STREE (P04043)
MTD22_STREE (P09358)
DsaV ^CCNGG N.A. 5mC MTD5_DACSA (P50185)
EcaI G^GTNACC N.A. 6mA MTEC_ENTCL (P14827)
Eco47I G^GWCC T2E7_ECOLX (P50194) ? N.A.
Eco47II G^GNCC T2E8_ECOLX (P50195) 5mC MTE8_ECOLX (P50196)
Eco57I CTGAAG (22); CTTCAG (-14) T257_ECOLX (P25239) 6mA MT57_ECOLX (P25240)
EcoRI G^AATTC T2E1_ECOLX (P00642) 6mA MTE1_ECOLX (P00472)
EcoRII ^CCWGG T2E2_ECOLX (P14633) 5mC MTE2_ECOLX (P05101)
EcoRV GAT^ATC T2E5_ECOLX (P04390) 6mA MTE5_ECOLX (P04393)
FnuDI GG^CC N.A. 5mC MTF1_FUSNU (P34906)
FokI GGATG (14); CATCC (-13) T2F1_PLAOK (P14870) 6mA MTF1_PLAOK (P14871)
HaeII RGCGC^Y T2H2_HAEAE (O30869) 5mC MTH2_HAEAE (O30868)
HaeIII GG^CC T2H3_HAEAE (O68584) 5mC MTH3_HAEAE (P20589)
HgaI GACGC (10); GCGTC (-10) T2G1_HAEGA (P43418) 5mC MTG1_HAEGA (P25282)
MTG2_HAEGA (P25283)
HgiBI G^GWCC T2B1_HERAU (P25257) 5mC MTB1_HERAU (P25262)
HgiCI G^GYRCC T2C1_HERAU (P25258) 5mC MTC1_HERAU (P25263)
HgiCII G^GWCC T2C2_HERAU (P25259) 5mC MTC2_HERAU (P25264)
HgiDI GR^CGYC T2D1_HERAU (P24599) 5mC MTD1_HERAU (P24600)
HgiDII G^TCGAC N.A. 5mC MTD2_HERAU (P25265)
HgiEI G^GWCC T2E1_HERAU (P25260) 5mC MTE1_HERAU (P25266)
HgiGI GR^CGYC T2G1_HERAU (P25261) 5mC MTG1_HERAU (P25267)
HhaI GCG^C N.A. 5mC MTH1_HAEPH (P05102)
HhaII G^ANTC T2H2_HAEPH (P00643) 6mA MTH2_HAEPH (P00473)
HincII GTY^RAC T2C2_HAEIF (P17743) 6mA MTHC_HAEIF (P17744)
HindII GTY^RAC T2D2_HAEIN (P44413) 6mA MTHD_HAEIN (P44414)
HindIII A^AGCTT T2D3_HAEIN (P43870) 6mA MTH3_HAEIN (P43871)
HindV GRCGYC T2D5_HAEIN (P44999) 5mC MTH5_HAEIN (P45000)
HinfI G^ANTC T2F1_HAEIF (P20588) 6mA MTH1_HAEIF (P20590)
HpaI GTT^AAC T2H1_HAEPA (P29537) 6mA MTH1_HAEPA (P29538)
HpaII C^CGG T2H2_HAEPA (P36433) 5mC MTH2_HAEPA (P15446)
HphI GGTGA (13); TCACC (-7) T2H1_HAEPH (P50191) 5mC MTHA_HAEPH (P50192)
6mA MTHB_HAEPH (P50193)
KpnI GGTAC^C T2K1_KLEPN (P25237) 6mA MTK1_KLEPN (P25238)
LlaDCHI ^GATC T2L2_LACLC (P50177) 6mA MTL21_LACLC (P50179)
MTL22_LACLC (P50178)
MamI GATNN^NNATC T2M1_MICAM (P50189) 6mA MTM1_MICAM (P50190)
MboI ^GATC T2M1_MORBO (P34719) 6mA MT1A_MORBO (P34720)
MT1B_MORBO (P34721)
MboII GAAGA (13); TCTTC (-7) T2M2_MORBO (P23191) 6mA MTM2_MORBO (P23192)
MjaI C^TAG T2M1_METJA (Q58391) 4mC MTM1_METJA (Q58392)
MjaII CCNG T2M2_METJA (Q58844) 4mC MTM2_METJA (Q58843)
MjaIII ^GATC T2M3_METJA (Q58017) 6mA MTM3_METJA (Q58015)
MjaIV GTNNAC T2M4_METJA (Q58723) ? MTM4_METJA (Q58724)
MjaV GTAC T2M5_METJA (Q58895) 4mC MTM5_METJA (Q58893)
MjaVI CCGG T2M6_METJA (P81326) 4mC MTM6_METJA (Q58606)
MspI C^CGG T2M1_MORSP (P11405) 5mC MTM1_MORSP (P11408)
MthTI GGCC T2MT_METTF (P29565) 5mC MTHT_METTF (P29567)
MthZI C^TAG T2MZ_METTF (P29566) 4mC MTHZ_METTF (P29568)
MunI C^AATTG T2MU_MYCSP (P43642) 6mA MTMU_MYCSP (P43641)
MvaI CC^WGG N.A. 4mC MTMV_MICVA (P14244)
MwoI GCNNNNN^NNGC T2MW_METWO (O59646) 4mC MTMW_METWO (O59647)
NaeI GCC^GGC T2N1_NOCAE (P50187) 5mC MTN1_NOCAE (P50188)
NgoBI RGCGC^Y T2B1_NEIGO (Q50973) 5mC MTB1_NEIGO (Q59603)
NgoBV GGN^NCC T2B5_NEIGO (Q50975) 5mC MTB5_NEIGO (Q59605)
NgoFVII GCSG^C T2F7_NEIGO (Q50976) 5mC MTF7_NEIGO (Q59606)
NgoMIV G^CCGGC T2M4_NEIGO (P31032) 5mC MTM4_NEIGO (P31033)
NgoPII GG^CC T2P2_NEIGO (P24617) 5mC MTP2_NEIGO (P08455)
NlaIII CATG^ T2N3_NEILA (Q51083) 6mA MTN3_NEILA (P24582)
NlaIV GGN^NCC T2N4_NEILA (P50183) 5mC MTN4_NEILA (P50182)
NmeDI ? T2D1_NEIMC (Q9RLM3) 5mC MTD1_NEIMC (Q9RLM4)
NspV TT^CGAA T2N5_NOSS7 (P35677) ? MTN5_NOSS7 (P35678)
PaeR7I C^TCGAG T2P7_PSEAI (P05104) 6mA MTP7_PSEAI (P05103)
PspPI G^GNCC N.A. 5mC MTP1_PSYTA (O33481)
PstI CTGCA^G T2PS_PROST (P00640) 6mA MTPS_PROST (P00474)
PvuI CGAT^CG T2P1_PROHU (P31031) ? N.A.
PvuII CAG^CTG T2P2_PROHU (P23657) 4mC MTP2_PROHU (P11409)
RsrI G^AATTC T2R1_RHOSH (P21763) 6mA MTR1_RHOSH (P14751)
SacI GAGCT^C T2S1_STRAH (O31074) 5mC MTS1_STRAH (O31073)
SalI G^TCGAC T2S1_STRAL (Q53608) 6mA MTS1_STRAL (Q53609)
Sau3AI ^GATC T2S3_STAAU (P16667) 5mC MTS3_STAAU (P16668)
Sau96I G^GNCC T2S9_STAAU (P23736) 5mC MTS9_STAAU (P23737)
ScaI AGT^ACT T2S1_STRCS (O52691) 4mC MTS1_STRCS (O52692)
ScrFI CC^NGG T2S1_LACLC (O34104) 5mC MTSA_LACLC (P34877)
MTSB_LACLC (P34878)
SfiI GGCCNNNN^NGGCC T2S1_STRFI (O52512) 4mC MTS1_STRFI (O52513)
SinI G^GWCC T2S1_SALIN (P09796) 5mC MTS1_SALIN (P09795)
SmaI CCC^GGG T2SM_SERMA (P14229) 4mC MTSM_SERMA (P14230)
SsoII ^CCNGG T2S2_SHISO (P34880) 5mC MTS2_SHISO (P34879)
StsI GGATG (15); CATCC (-14) T2S1_STRSA (P29346) 6mA MTS1_STRSA (P29347)
TaqI T^CGA T2TA_THEAQ (P14386) 6mA MTTA_THEAQ (P14385)
TthHB8I T^CGA T2T8_THET8 (P29748) 6mA MTT8_THET8 (P29749)
VspI AT^TAAT N.A. 6mA MTV1_VIBS3 (Q03055)
XamI G^TCGAC T2X1_XANCR (P96189) 6mA MTX1_XANCR (P96188)
XcyI C^CCGGG T2X1_XANCC (P30773) 4mC MTX1_XANCC (P30774)
XhoI C^TCGAG T2X1_XANVA (Q9KVZ7) 6mA MTX1_XANVA (Q9KVZ8)
XorII CGATC^G N.A. 5mC MTX2_XANOR (P52311)
M.BabI GANTC 6mA MTB1_BRUAB (P0C116)
MTB1_BRUA2 (Q2YMK2)
M.BsuSpb GGCC; GCNGC 5mC MTBB_BPSPB (P09389)
M.BsuSprI GGCC; CCGG 5mC MTBS_BPSPR (P00476)
M.CcrmI GANTC 6mA MTC1_CAUCN (B8GZ33)
M.CviBIII TCGA 6mA MTC3_PBCVC (P10835)
M.EcoDcm CCWGG 5mC DCM_ECOLI (P0AED9)
M.EcoDcm CCWGG 5mC DCM_ECO57 (P0AEE0)
M.EcoDam GATC 6mA DMA_ECOLI (P0AEE8)
M.EcoDam GATC 6mA DMA_ECO57 (P0AEE9)
M.EcoT2Dam GATC 6mA DMA_BPT2 (P12427)
M.EcoT4Dam GATC 6mA DMA_BPT4 (P04392)
M.Eco67Dam GATC 6mA DMA7_ECOLX (P21311)
M.HindIV GATC 6mA DMA_HAEIN (P44431)
M.LlaI ? 6mA MTL1_LACLL (P35516)
M.NlaX CCNGG 5mC MTNX_NEILA (P24581)
M.Phi3TI GGCC; GCNGC 5mC MTBP_BACSU (P68585)
M.Phi3TI GGCC; GCNGC 5mC MTBP_BPPHT (P68586)
M.Rho11sI GGCC; GAGCTC 5mC MTBR_BPRH1 (P09915)
M.SmaII GATC 6mA DMA_SERMA (P45454)
M.SmeI GANTC 6mA MTS1_RHIME (O30569)
M.StyDam GATC 6mA DMA_SALTY (P0A291)
M.SPbetaI GGCC 5mC MTBB_BPSPB (P09389)
M.SPRI GGCC 5mC MTBS_BPSPR (P00476)
M.SssI CG 5mC MTSI_SPISQ (P15840)
M.SpomI CCWGG 5mC PMT1M_SCHPO (P40999)
M.TpaI GATC 6mA DMA_TREPA (O33844)
M.VchADam GATC 6mA DMA_VIBCH (P0C6Q8)
==============
Type I enzymes
==============
_________ ___________ ____________________ ____________________ ____________________
Name of Recognition S protein R protein M protein
enzyme sequence Entry name AC Entry name AC Entry name AC
_________ ___________ ____________________ ____________________ ____________________
EcoAI GAGN(7)GTCA T1SA_ECOLX (P19704) T1RA_ECOLX (Q07736) N.A.
EcoBI TGAN(8)TGCT T1SB_ECOLX (P06990) N.A. N.A.
EcoDI TTAN(7)GTCY T1SD_ECOLX (P06991) N.A. N.A.
EcoEI GAGN(7)ATGC T1SE_ECOLX (P19705) T1RE_ECOLX (Q47281) T1ME_ECOLX (Q47282)
EcoKI AACN(6)GTGC T1SK_ECOLI (P05719) T1RK_ECOLI (P08956) T1MK_ECOLI (P08957)
EcoprrI CCAN(7)ATGC T1SP_ECOLX (P17222) T1RP_ECOLX (P17224) T1MP_ECOLX (Q47163)
EcoR124II GAAN(6)RTCG T1S1_ECOLX (P10485) T1R1_ECOLX (P10486) T1M1_ECOLX (P10484)
StySPI AACN(6)GTRC T1S_SALPO (P07990) N.A. T1M_SALPO (P07989)
StySJI GAGN(6)GTRC T1S_SALTY (P06187) N.A. T1M_SALTY (P40813)
MjaX ? T1SH_METJA (Q60296) T1RH_METJA (Q60295) T1MH_METJA (Q60297)
_________ ___________ ____________________ ____________________ ____________________
================
Type III enzymes
================
__________ _________________________ ____________________ ____________________
Name of Recognition sequence Mod protein Res protein
enzyme Entry name AC Entry name AC
__________ _________________________ ____________________ ____________________
EcoPI AGACC (?); GGTCT (?) T3MO_BPP1 (P08763) T3RE_BPP1 (P08764)
EcoP15I CAGCAG (31); CTGCTG (-27) T3MO_ECOLX (P12364) N.A.
StyLTI CAGAG (?); CTCTG (?) T3MO_SALTY (P40814) T3RE_SALTY (P40815)
Bce10987IP ?; ? N.A. T3RE_BACC1 (P25241)
HindVIP ?; ? T3MH_HAEIN (P71366) T3RH_HAEIN (P44105)
__________ _________________________ ____________________ ____________________
===============
Type IV enzymes
===============
_________ ____________________________________ ____________________ ____________________
Name of Recognition sequence Subunit A Subunit B
enzyme entry name AC entry name AC
_________ ____________________________________ ____________________ ____________________
BcgI GCANNNNNNTCG (24) CGANNNNNNTGC (-10) T4BA_BACCO (Q07605) T4BB_BACCO (Q07606)
CGANNNNNNTGC (24) GCANNNNNNTCG (-10)
_________ ____________________________________ ____________________ ____________________
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