bloodgrp.txt
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UniProt - Swiss-Prot Protein Knowledgebase
SIB Swiss Institute of Bioinformatics; Geneva, Switzerland
European Bioinformatics Institute (EBI); Hinxton, United Kingdom
Protein Information Resource (PIR); Washington DC, USA
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Description: Blood group antigen proteins: list of entries
Name: bloodgrp.txt
Release: 2013_06 of 29-May-2013
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This file is a summary of the human proteins that are responsible for the
molecular basis of the blood group antigens. Blood group antigens are surface
markers on the outside of the red blood cell membrane. Most of them are
proteins, but some are carbohydrates attached to lipids or proteins.
A good source of information on blood group antigens can be found in:
Reid M.E., Lomas-Francis C.
The Blood Group Antigen FactsBook
Academic Press, London / San Diego, (1997).
Blood group antigen mutation database:
http://www.ncbi.nlm.nih.gov/projects/mhc/xslcgi.fcgi?cmd=bgmut/home
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Blood Group Carrier or effector protein name
system Gene name
Swiss-Prot cross reference
Antigen names
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ABO Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase
(EC 2.4.1.40) (Histo-blood group A transferase) /
Fucosylglycoprotein 3-alpha-galactosyltransferase (EC 2.4.1.37)
(Histo-blood group B transferase).
Gene: ABO
BGAT_HUMAN (P16442)
Antigens: A/B
Chido/Rodgers Complement C4.
Gene: C4A and C4B
CO4A_HUMAN (P0C0L4)
CO4B_HUMAN (P0C0L5)
Antigens: Ch1 to Ch6, WH, Rg1, Rg2
Colton Aquaporin-1 (AQP-1) (Aquaporin-CHIP) (Water channel protein
for red blood cells and kidney proximal tubule) (Urine
water channel).
Gene: AQP1; CHIP28
AQP1_HUMAN (P29972)
Antigens: Co(a/b)
Cromer Complement decay-accelerating factor (CD55 antigen).
Gene: DAF; CD55
DAF_HUMAN (P08174)
Antigens: Cr(a), Dr(a), Es(a), Tc(a/b/c), Wd(a), WES(a/b),
IFC, UMC, GUTI
Diego Band 3 anion transport protein (Anion exchange protein 1)
(AE 1) (Solute carrier family 4 member 1) (CD233 antigen).
Gene: SLC4A1; AE1; EPB3; DI
B3AT_HUMAN (P02730)
Antigens: Di(a/b), FR(a/a+), Wr(a/b), Wd(a), Rb(a), WARR, ELO,
BOW, Wu, Vg(a), Bp(a), Hg(a), Mo(a), Sw(a), Tr(a)
Dombrock Ecto-ADP-ribosyltransferase 4 (EC 2.4.2.31) (NAD(P)(+)--
arginine ADP-ribosyltransferase 4) (Mono(ADP-ribosyl)
transferase 4) (Dombrock blood group carrier molecule) (CD97
antigen).
Gene: ART4; D0; DOK1
NAR4_HUMAN (Q93070)
Antigens: Do(a/b), Gy(a), Hy, Jo(A)
Duffy Duffy antigen (Fy glycoprotein) (Glycoprotein D) (GpFy)
(CD234 antigen).
Gene: FY; GPD; DARC
DUFFY_HUMAN (Q16570)
Antigens: Fy(a/b)
Gerbich Glycophorin-C (PAS-2') (Glycoprotein beta) (Glycoconnectin)
(Sialoglycoprotein-D) (Glycophorin-D) (GpD).
Gene: GYPC; GPC
GLPC_HUMAN (P04921)
Antigens: An(a), Dh(A), Ls(a), Wb
GIL Aquaporin-3 (AQP-3).
Gene: AQP3
AQP3_HUMAN (Q92482)
Hh Galactoside 2-L-fucosyltransferase 1 (EC 2.4.1.69)
(Alpha(1,2)Ft 1) (Fucosyltransferase 1).
Gene: FUT1
FUT1_HUMAN (P19526)
Galactoside 2-L-fucosyltransferase 2 (EC 2.4.1.69)
(Alpha(1,2)Ft 2) (Fucosyltransferase 2) (Secretor factor).
Gene: FUT2
FUT2_HUMAN (Q10981)
Antigens: H/h, Se/se
Indian CD44 antigen (Phagocytic glycoprotein I) (PGP-1) (Hutch-I)
(Extracellular matrix receptor-III) (ECMR-III) (Hermes antigen)
(Hyaluronate receptor) (Heparan sulfate proteoglycan) (Epican).
Gene: CD44; LHR
CD44_HUMAN (P16070)
Antigens: In(a/b)
John-Milton- Semaphorin-7A (Semaphorin-L) (Sema L) (Semaphorin-K1)
Hargen (Sema K1) (CD108 antigen) (CDw108).
Gene: SEMA7A; SEMAL; CD108
SEM7A_HUMAN (O75326)
Kell Kell blood group glycoprotein (EC 3.4.24.-) (CD238 antigen).
Gene: KEL
KELL_HUMAN (P23276)
Antigens: K/k, Kp(a/b/c), Js(a/b), Ul(a), KEL11/17, KEL14/24
Kidd Urea transporter, erythrocyte.
Gene: SLC14A1; HUT11; JK; RACH1; UT1; UTE
UT1_HUMAN (Q13336)
Antigens: Jk(a/b)
Knops Complement receptor type 1 (C3b/C4b receptor) (CD35 antigen).
Gene: CR1; C3BR
CR1_HUMAN (P17927)
Antigens: Kn(a/b), McC(a), Sl(a), Vl, Yk(a)
Kx Membrane transport protein XK (Kx antigen).
Gene: XK
XK_HUMAN (P51811)
Landsteiner- Intercellular adhesion molecule-4 (ICAM-4)
Wiener (Landsteiner-Wiener blood group glycoprotein) (LW blood
group protein) (CD242 antigen).
Gene: ICAM4; LW
ICAM4_HUMAN (Q14773)
Antigens: LW(a/b)
Lewis Galactoside 3(4)-L-fucosyltransferase (EC 2.4.1.65)
(Fucosyltransferase 3) (FUCT-III).
Gene: FUT3; LE
FUT3_HUMAN (P21217)
Antigens: Le(a/b)
Lutheran Lutheran blood group glycoprotein (B-CAM cell surface
glycoprotein) (Auberger B antigen) (F8/G253 antigen)
(CD239 antigen).
Gene: BCAM; LU; MSK19
BCAM_HUMAN (P50895)
Antigens: Lu(a/b), Au(a/b), LU6 to LU20
MNS Glycophorin-A (PAS-2) (Sialoglycoprotein alpha) (MN
sialoglycoprotein) (CD235a antigen).
Gene: GYPA; GPA
GLPA_HUMAN (P02724)
Glycophorin-B (PAS-3) (Sialoglycoprotein delta) (SS-active
sialoglycoprotein) (CD235b anrigen).
Gene: GYPB; GPB
GLPB_HUMAN (P06028)
Antigens: M/N, S/s, U, He, Mi(a), M(c), Vw, Mur, M(g), Vr,
M(e), Mt(a), St(a), Ri(a), Cl(a), Ny(a), Hut, Hil,
M(v), Far, Mit, Dantu, Hop, Nob, En(a), ENKT, etc.
OK Basigin (Leukocyte activation antigen M6) (Collagenase
stimulatory factor) (Extracellular matrix metalloproteinase inducer)
(EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor)
(TCSF) (OK blood group antigen) (CD147 antigen).
Gene: BSG
BASI_HUMAN (P35613)
Antigen: Ok
P UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1
(EC 2.4.1.79) (Beta-1,3-galactosyltransferase 3) (Beta-1,3-
GalTase 3) (Beta3Gal-T3) (b3Gal-T3)
(Galactosylgalactosylglucosylceramide beta-D-acetyl-
galactosaminyltransferase) (Globoside synthase).
Gene: B3GALN1; B3GALT3
B3GL1_HUMAN (O75752)
Antigens: P1
RAPH CD151 antigen (Platelet-endothelial tetraspan antigen 3)
(PETA-3) (GP27) (Membrane glycoprotein SFA-1) (Tetraspanin-24)
(Tspan-24).
Gene: CD151; TSPAN24
CD151_HUMAN (P48509)
Antigens: MER2
Rh Blood group RH(CE) polypeptide (Rhesus C/E antigens) (RHPI)
(CD240CE antigen).
Gene: RHCE; RHC; RHE
RHCE_HUMAN (P18577)
Blood group RH(D) polypeptide (Rhesus D antigen) (RHPII)
(CD240D antigen).
Gene: RHD
RHD_HUMAN (Q02161)
Antigens: C/c, E/e, D, f, C(e), C(w), C(x), V, E(w), G, Tar,
VS, D(w), cE, etc.
Scianna/ Erythroid membrane-associated protein (hERMAP) (Scianna
Radin blood group antigen) (Radin blood group antigen).
Gene: ERMAP; RD; SC
ERMAP_HUMAN (Q96PL5)
Antigens: Sc(1/2), Sc3, Sc4/Rd, Sc5/STAR, Sc6/SCER, Sc7/SCAN
Xg Glycoprotein Xg (Protein PBDX).
Gene: XG; PBDX
XG_HUMAN (P55808)
Antigens: Xg(a)
Yt Acetylcholinesterase (EC 3.1.1.7) (AChE).
Gene: ACHE
ACES_HUMAN (P22303)
Antigens: Yt(a/b)
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