Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Definition

A complex neurodegenerative disorder with manifestations ranging from typical Parkinson disease to dementia with Lewy bodies. Clinical features include parkinsonian symptoms (resting tremor, rigidity, postural instability and bradykinesia), dementia, diffuse Lewy body pathology, autonomic dysfunction, hallucinations and paranoia.

Acronym

PARK4

Synonyms

Parkinson disease 4 autosomal dominant Lewy body
Parkinson disease autosomal dominant 4
Parkinson disease familial type 4

Keywords

Neurodegeneration
Parkinson disease
Parkinsonism

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.