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13 results for author:"Zvelebil M.J." in Literature citations

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The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer .

Folkes A.J., Ahmadi K., Alderton W.K., Alix S., Baker S.J., Box G., Chuckowree I.S., Clarke P.A., Depledge P., Eccles S.A. et al.

J. Med. Chem. 51:5522-5532(2008) · Mapped (1)

Cluster analysis of an extensive human breast cancer cell line protein expression map database.

Harris R.A., Yang A., Stein R.C., Lucy K., Brusten L., Herath A., Parekh R., Waterfield M.D., O'Hare M.J., Neville M.A. et al.

Proteomics 2:212-223(2002) · UniProtKB (19)

Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors.

Arcaro A., Zvelebil M.J., Wallasch C., Ullrich A., Waterfield M.D., Domin J.

Mol. Cell. Biol. 20:3817-3830(2000) · UniProtKB (5)

Identification of germline missense mutations and rare allelic variants in the ATM gene in early-onset breast cancer.

Izatt L., Greenman J., Hodgson S.V., Ellis D., Watts S., Scott G., Jacobs C., Liebmann R., Zvelebil M.J., Mathew C. et al.

Genes Chromosomes Cancer 26:286-294(1999) · UniProtKB (1)

Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity.

Arcaro A., Volinia S., Zvelebil M.J., Stein R.C., Watton S.J., Layton M.J., Gout I., Ahmadi K., Downward J., Waterfield M.D.

J. Biol. Chem. 273:33082-33090(1998) · UniProtKB (1)

1H NMR structure of an antifungal gamma-thionin protein SIalpha1: similarity to scorpion toxins.

Bloch C. Jr., Patel S.U., Baud F., Zvelebil M.J., Carr M.D., Sadler P.J., Thornton J.M.

Proteins 32:334-349(1998) · UniProtKB (1)

Cloning of a human phosphoinositide 3-kinase with a C2 domain which displays reduced sensitivity to the inhibitor wortmannin.

Domin J., Pages F., Volinia S., Rittenhouse S.E., Zvelebil M.J., Stein R.C., Waterfield M.D.

Biochem. J. 326:139-147(1997) · UniProtKB (1)

P110delta, a novel phosphoinositide 3-kinase in leukocytes.

Vanhaesebroeck B.A.M., Welham M.J., Kotani K., Stein R., Warne P.H., Zvelebil M.J., Higashi K., Volinia S., Downward J., Waterfield M.D.

Proc. Natl. Acad. Sci. U.S.A. 94:4330-4335(1997) · UniProtKB (1)

Three-dimensional solution structure of the pleckstrin homology domain from dynamin.

Downing A.K., Driscoll P.C., Gout I., Salim K., Zvelebil M.J., Waterfield M.D.

Curr. Biol. 4:884-891(1994) · UniProtKB (1)

A novel point mutation in the tyrosine kinase domain of the RET proto-oncogene in sporadic medullary thyroid carcinoma and in a family with FMTC.

Eng C., Smith D.P., Mulligan L.M., Healey C.S., Zvelebil M.J., Stonehouse T.J., Ponder M.A., Jackson C.E., Waterfield M.D., Ponder B.A.J.

Oncogene 10:509-513(1995) · UniProtKB (1)

Molecular modelling and epitope prediction of gp29 from lymphatic filariae.

Zvelebil M.J.J.M., Tang L., Cookson E., Selkirk M.E., Thornton J.M.

Mol. Biochem. Parasitol. 58:145-153(1993) · UniProtKB (2)

A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system.

Volinia S., Dhand R., Vanhaesebroeck B., MacDougall L.K., Zvelebil M.J., Domin J., Panaretou C., Waterfield M.D.

EMBO J. 14:3339-3348(1995) · UniProtKB (1) · Mapped (2)

A pyruvate-stimulated adenylate cyclase has a sequence related to the fes/fps oncogenes and to eukaryotic cyclases.

Peters E.P., Wilderspin A.F., Wood S.P., Zvelebil M.J.J.M., Sezer O., Danchin A.

Mol. Microbiol. 5:1175-1181(1991) · UniProtKB (1)

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