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Nonmuscle myosin IIB links cytoskeleton to IRE1alpha signaling during ER stress.

He Y., Beatty A., Han X., Ji Y., Ma X., Adelstein R.S., Yates J.R., Kemphues K., Qi L.

Dev. Cell 23:1141-1152(2012) · Mapped (9)

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2.

Liu G.H., Qu J., Suzuki K., Nivet E., Li M., Montserrat N., Yi F., Xu X., Ruiz S., Zhang W. et al.

Nature 491:603-607(2012) · Mapped (4)

O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1alpha stability.

Ruan H.B., Han X., Li M.D., Singh J.P., Qian K., Azarhoush S., Zhao L., Bennett A.M., Samuel V.T., Wu J. et al.

Cell Metab. 16:226-237(2012) · Mapped (2)

Modulation of dynamin-related protein 1 (DRP1) function by increased O-linked-beta-N-acetylglucosamine modification (O-GlcNAc) in cardiac myocytes.

Gawlowski T., Suarez J., Scott B., Torres-Gonzalez M., Wang H., Schwappacher R., Han X., Yates J.R. III, Hoshijima M., Dillmann W.

J. Biol. Chem. 287:30024-30034(2012) · UniProtKB (1) · Mapped (13)

Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.

Cipriani V., Leung H.T., Plagnol V., Bunce C., Khan J.C., Shahid H., Moore A.T., Harding S.P., Bishop P.N., Hayward C. et al.

Hum. Mol. Genet. 21:4138-4150(2012) · Mapped (19)

FANCL ubiquitinates beta-catenin and enhances its nuclear function.

Dao K.H., Rotelli M.D., Petersen C.L., Kaech S., Nelson W.D., Yates J.E., Hanlon Newell A.E., Olson S.B., Druker B.J., Bagby G.C.

Blood 120:323-334(2012) · Mapped (11)

Arginylation regulates myofibrils to maintain heart function and prevent dilated cardiomyopathy.

Kurosaka S., Leu N.A., Pavlov I., Han X., Ribeiro P.A., Xu T., Bunte R., Saha S., Wang J., Cornachione A. et al.

J. Mol. Cell. Cardiol. 53:333-341(2012) · Mapped (7)

Proteomic analysis of wild-type and mutant huntingtin-associated proteins in mouse brains identifies unique interactions and involvement in protein synthesis.

Culver B.P., Savas J.N., Park S.K., Choi J.H., Zheng S., Zeitlin S.O., Yates J.R., Tanese N.

J. Biol. Chem. 287:21599-21614(2012) · Mapped (6)

Calcium signaling through CaMKII regulates hepatic glucose production in fasting and obesity.

Ozcan L., Wong C.C., Li G., Xu T., Pajvani U., Park S.K., Wronska A., Chen B.X., Marks A.R., Fukamizu A. et al.

Cell Metab. 15:739-751(2012) · Mapped (14)

PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential.

Shia W.J., Okumura A.J., Yan M., Sarkeshik A., Lo M.C., Matsuura S., Komeno Y., Zhao X., Nimer S.D., Yates J.R. et al.

Blood 119:4953-4962(2012) · Mapped (8)

Viral E3 ubiquitin ligase-mediated degradation of a cellular E3: viral mimicry of a cellular phosphorylation mark targets the RNF8 FHA domain.

Chaurushiya M.S., Lilley C.E., Aslanian A., Meisenhelder J., Scott D.C., Landry S., Ticau S., Boutell C., Yates J.R. III, Schulman B.A. et al.

Mol. Cell 46:79-90(2012) · UniProtKB (2)

FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development.

O'Sullivan M.L., de Wit J., Savas J.N., Comoletti D., Otto-Hitt S., Yates J.R., Ghosh A.

Neuron 73:903-910(2012) · Mapped (7)

Proteomic analysis of mammalian primary cilia.

Ishikawa H., Thompson J., Yates J.R., Marshall W.F.

Curr. Biol. 22:414-419(2012) · Mapped (24)

Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype.

Sofat R., Casas J.P., Webster A.R., Bird A.C., Mann S.S., Yates J.R., Moore A.T., Sepp T., Cipriani V., Bunce C. et al.

Int J Epidemiol 41:250-262(2012) · Mapped (5)

p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytes.

Anur P., Yates J., Garbati M.R., Vanderwerf S., Keeble W., Rathbun K., Hays L.E., Tyner J.W., Svahn J., Cappelli E. et al.

Blood 119:1992-2002(2012) · Mapped (12)

Histone H3 lysine 14 acetylation is required for activation of a DNA damage checkpoint in fission yeast.

Wang Y., Kallgren S.P., Reddy B.D., Kuntz K., Lopez-Maury L., Thompson J., Watt S., Ma C., Hou H., Shi Y. et al.

J. Biol. Chem. 287:4386-4393(2012) · UniProtKB (7)

Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway.

Jeong H., Cohen D.E., Cui L., Supinski A., Savas J.N., Mazzulli J.R., Yates J.R., Bordone L., Guarente L., Krainc D.

Nat. Med. 18:159-165(2012) · Mapped (22)

Wall teichoic acids of Staphylococcus aureus limit recognition by the drosophila peptidoglycan recognition protein-SA to promote pathogenicity.

Atilano M.L., Yates J., Glittenberg M., Filipe S.R., Ligoxygakis P.

PLoS Pathog. 7:e1002421-e1002421(2011) · Mapped (4)

hnRNP A1 and hnRNP F modulate the alternative splicing of exon 11 of the insulin receptor gene.

Talukdar I., Sen S., Urbano R., Thompson J., Yates J.R., Webster N.J.

PLoS ONE 6:e27869-e27869(2011) · Mapped (22)

The zipcode-binding protein ZBP1 influences the subcellular location of the Ro 60-kDa autoantigen and the noncoding Y3 RNA.

Sim S., Yao J., Weinberg D.E., Niessen S., Yates J.R., Wolin S.L.

RNA 18:100-110(2012) · Mapped (10)

Complement factor D in age-related macular degeneration.

Stanton C.M., Yates J.R., den Hollander A.I., Seddon J.M., Swaroop A., Stambolian D., Fauser S., Hoyng C., Yu Y., Atsuhiro K. et al.

Invest. Ophthalmol. Vis. Sci. 52:8828-8834(2011) · Mapped (3)

The functioning of the Drosophila CPEB protein Orb is regulated by phosphorylation and requires casein kinase 2 activity.

Wong L.C., Costa A., McLeod I., Sarkeshik A., Yates J., Kyin S., Perlman D., Schedl P.

PLoS ONE 6:e24355-e24355(2011) · Mapped (24)

Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies.

McKay G.J., Patterson C.C., Chakravarthy U., Dasari S., Klaver C.C., Vingerling J.R., Ho L., de Jong P.T., Fletcher A.E., Young I.S. et al.

Hum. Mutat. 32:1407-1416(2011) · Mapped (5)

Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor.

Paramasivam M., Sarkeshik A., Yates J.R., Fernandes M.J., McCollum D.

Mol. Biol. Cell 22:3725-3733(2011) · Mapped (6)

Essential role of Stat3 in PI3K-induced oncogenic transformation.

Hart J.R., Liao L., Yates J.R., Vogt P.K.

Proc. Natl. Acad. Sci. U.S.A. 108:13247-13252(2011) · Mapped (28)

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