| Exogenous and endogenous ghrelin counteracts GLP-1 action to stimulate cAMP signaling and insulin secretion in islet beta-cells. Damdindorj B., Dezaki K., Kurashina T., Sone H., Rita R., Kakei M., Yada T.
FEBS Lett. 586:2555-2562(2012) · Mapped (5) |
| Ghrelin attenuates cAMP-PKA signaling to evoke insulinostatic cascade in islet beta-cells. Dezaki K., Damdindorj B., Sone H., Dyachok O., Tengholm A., Gylfe E., Kurashina T., Yoshida M., Kakei M., Yada T.
Diabetes 60:2315-2324(2011) · Mapped (4) |
| PDK1-Foxo1 in agouti-related peptide neurons regulates energy homeostasis by modulating food intake and energy expenditure. Cao Y., Nakata M., Okamoto S., Takano E., Yada T., Minokoshi Y., Hirata Y., Nakajima K., Iskandar K., Hayashi Y. et al.
PLoS ONE 6:e18324-e18324(2011) · Mapped (15) |
| Nesfatin-1 enhances glucose-induced insulin secretion by promoting Ca(2+) influx through L-type channels in mouse islet beta-cells. Nakata M., Manaka K., Yamamoto S., Mori M., Yada T.
Endocr. J. 58:305-313(2011) · Mapped (3) |
| Lack of TRPM2 impaired insulin secretion and glucose metabolisms in mice. Uchida K., Dezaki K., Damdindorj B., Inada H., Shiuchi T., Mori Y., Yada T., Minokoshi Y., Tominaga M.
Diabetes 60:119-126(2011) · Mapped (4) |
| Changes in prolactin mRNA levels during downstream migration of the amphidromous teleost, ayu Plecoglossus altivelis. Yada T., Tsuruta T., Sakano H., Yamamoto S., Abe N., Takasawa T., Yogo S., Suzuki T., Iguchi K., Uchida K. et al.
Gen. Comp. Endocrinol. 167:261-267(2010) · UniProtKB (1) |
| PDK-1/FoxO1 pathway in POMC neurons regulates Pomc expression and food intake. Iskandar K., Cao Y., Hayashi Y., Nakata M., Takano E., Yada T., Zhang C., Ogawa W., Oki M., Chua S. Jr. et al.
Am. J. Physiol. Endocrinol. Metab. 298:E787-98(2010) · Mapped (34) |
| Endogenous prolactin-releasing peptide regulates food intake in rodents. Takayanagi Y., Matsumoto H., Nakata M., Mera T., Fukusumi S., Hinuma S., Ueta Y., Yada T., Leng G., Onaka T.
J. Clin. Invest. 118:4014-4024(2008) · Mapped (18) |
| Leptin transiently antagonizes ghrelin and long-lastingly orexin in regulation of Ca2+ signaling in neuropeptide Y neurons of the arcuate nucleus. Kohno D., Suyama S., Yada T.
World J. Gastroenterol. 14:6347-6354(2008) · Mapped (2) |
| Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice. Takaki A., Morikawa K., Tsutsui M., Murayama Y., Tekes E., Yamagishi H., Ohashi J., Yada T., Yanagihara N., Shimokawa H.
J. Exp. Med. 205:2053-2063(2008) · Mapped (7) |
| Sub-chronic stimulation of glucocorticoid receptor impairs and mineralocorticoid receptor protects cytosolic Ca2+ responses to glucose in pancreatic beta-cells. Koizumi M., Yada T.
J. Endocrinol. 197:221-229(2008) · Mapped (4) |
| Nesfatin-1 neurons in paraventricular and supraoptic nuclei of the rat hypothalamus coexpress oxytocin and vasopressin and are activated by refeeding. Kohno D., Nakata M., Maejima Y., Shimizu H., Sedbazar U., Yoshida N., Dezaki K., Onaka T., Mori M., Yada T.
Endocrinology 149:1295-1301(2008) · Mapped (2) |
| Role of Cu,Zn-SOD in the synthesis of endogenous vasodilator hydrogen peroxide during reactive hyperemia in mouse mesenteric microcirculation in vivo. Yada T., Shimokawa H., Morikawa K., Takaki A., Shinozaki Y., Mori H., Goto M., Ogasawara Y., Kajiya F.
Am. J. Physiol. Heart Circ. Physiol. 294:H441-8(2008) · Mapped (2) |
| Synaptic interaction between ghrelin- and ghrelin-containing neurons in the rat hypothalamus. Hori Y., Kageyama H., Guan J.L., Kohno D., Yada T., Takenoya F., Nonaka N., Kangawa K., Shioda S., Yoshida T.
Regul. Pept. 145:122-127(2008) · Mapped (3) |
| Cannabinoids inhibit insulin secretion and cytosolic Ca2+ oscillation in islet beta-cells via CB1 receptors. Nakata M., Yada T.
Regul. Pept. 145:49-53(2008) · Mapped (2) |
| Ghrelin uses Galphai2 and activates voltage-dependent K+ channels to attenuate glucose-induced Ca2+ signaling and insulin release in islet beta-cells: novel signal transduction of ghrelin. Dezaki K., Kakei M., Yada T.
Diabetes 56:2319-2327(2007) · Mapped (11) |
| Fluvastatin reverses endothelial dysfunction and increased vascular oxidative stress in rat adjuvant-induced arthritis. Haruna Y., Morita Y., Yada T., Satoh M., Fox D.A., Kashihara N.
Arthritis Rheum. 56:1827-1835(2007) · Mapped (2) |
| PACAP in the glucose and energy homeostasis: physiological role and therapeutic potential. Nakata M., Yada T.
Curr. Pharm. Des. 13:1105-1112(2007) · Mapped (4) |
| Leptin suppresses ghrelin-induced activation of neuropeptide Y neurons in the arcuate nucleus via phosphatidylinositol 3-kinase- and phosphodiesterase 3-mediated pathway. Kohno D., Nakata M., Maekawa F., Fujiwara K., Maejima Y., Kuramochi M., Shimazaki T., Okano H., Onaka T., Yada T.
Endocrinology 148:2251-2263(2007) · Mapped (4) |
| Oleic acid glucose-independently stimulates glucagon secretion by increasing cytoplasmic Ca2+ via endoplasmic reticulum Ca2+ release and Ca2+ influx in the rat islet alpha-cells. Fujiwara K., Maekawa F., Dezaki K., Nakata M., Yashiro T., Yada T.
Endocrinology 148:2496-2504(2007) · Mapped (2) |
| Resistin induces insulin resistance in pancreatic islets to impair glucose-induced insulin release. Nakata M., Okada T., Ozawa K., Yada T.
Biochem. Biophys. Res. Commun. 353:1046-1051(2007) · Mapped (3) |
| Expression of retinaldehyde dehydrogenase (RALDH)2 and RALDH3 but not RALDH1 in the developing anterior pituitary glands of rats. Fujiwara K., Maekawa F., Kikuchi M., Takigami S., Yada T., Yashiro T.
Cell Tissue Res. 328:129-135(2007) · Mapped (3) |
| Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance. Dezaki K., Sone H., Koizumi M., Nakata M., Kakei M., Nagai H., Hosoda H., Kangawa K., Yada T.
Diabetes 55:3486-3493(2006) · Mapped (7) |
| Young adult-specific hyperphagia in diabetic Goto-kakizaki rats is associated with leptin resistance and elevation of neuropeptide Y mRNA in the arcuate nucleus. Maekawa F., Fujiwara K., Kohno D., Kuramochi M., Kurita H., Yada T.
J. Neuroendocrinol. 18:748-756(2006) · Mapped (3) |
| Leptin facilitates learning and memory performance and enhances hippocampal CA1 long-term potentiation and CaMK II phosphorylation in rats. Oomura Y., Hori N., Shiraishi T., Fukunaga K., Takeda H., Tsuji M., Matsumiya T., Ishibashi M., Aou S., Li X.L. et al.
Peptides 27:2738-2749(2006) · Mapped (1) |
