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Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.

Sun L., Wu J., Du F., Chen X., Chen Z.J.

Science 339:786-791(2013) · UniProtKB (3)

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.

Wu J., Sun L., Chen X., Du F., Shi H., Chen C., Chen Z.J.

Science 339:826-830(2013) · UniProtKB (2)

A PGC-1alpha isoform induced by resistance training regulates skeletal muscle hypertrophy.

Ruas J.L., White J.P., Rao R.R., Kleiner S., Brannan K.T., Harrison B.C., Greene N.P., Wu J., Estall J.L., Irving B.A. et al.

Cell 151:1319-1331(2012) · UniProtKB (3) · Mapped (10)

Complete genome sequence of porcine circovirus 2b strain Shandong.

Xu S., Li J., Yuan X., Wang G., Shi J., Wu J., Cong X., Sun W., Du Y., Chai T. et al.

J. Virol. 86:13885-13885(2012) · UniProtKB (1)

Complete genome sequence of a moderately pathogenic porcine reproductive and respiratory syndrome virus variant strain.

Du Y., Lu Y., Qi J., Wu J., Wang G., Wang J.

J. Virol. 86:13883-13884(2012) · UniProtKB (8)

Complete genome sequence of recombinant porcine circovirus type 2 strain SD-3.

Li J., Xu S., Yuan X., Wang G., Shi J., Wu J., Cong X., Sun W., Du Y., Wang J.

J. Virol. 86:13870-13870(2012) · UniProtKB (2)

Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation.

Leeper N.J., Raiesdana A., Kojima Y., Kundu R.K., Cheng H., Maegdefessel L., Toh R., Ahn G.O., Ali Z.A., Anderson D.R. et al.

Arterioscler. Thromb. Vasc. Biol. 33:e1-e10(2013) · Mapped (62)

A Protein⋅Protein Interaction Platform Involved in Recruitment of GLD-3 to the FBF⋅fem-3 mRNA Complex.

Wu J., Campbell Z.T., Menichelli E., Wickens M., Williamson J.R.

J. Mol. Biol. 425:738-754(2013) · Mapped (3)

Biochemical Characterization of the Caenorhabditis elegans FBF⋅CPB-1 Translational Regulation Complex Identifies Conserved Protein Interaction Hotspots.

Menichelli E., Wu J., Campbell Z.T., Wickens M., Williamson J.R.

J. Mol. Biol. 425:725-737(2013) · Mapped (4)

Disruption of PH-kinase domain interactions leads to oncogenic activation of AKT in human cancers.

Parikh C., Janakiraman V., Wu W.I., Foo C.K., Kljavin N.M., Chaudhuri S., Stawiski E., Lee B., Lin J., Li H. et al.

Proc. Natl. Acad. Sci. U.S.A. 109:19368-19373(2012) · Mapped (5)

Inhibition of hydrogen sulfide generation contributes to lung injury after experimental orthotopic lung transplantation.

Wu J., Wei J., You X., Chen X., Zhu H., Zhu X., Liu Y., Xu M.

J. Surg. Res. 0:0-0(2012) · Mapped (2)

Structural insight into the type-II mitochondrial NADH dehydrogenases.

Feng Y., Li W., Li J., Wang J., Ge J., Xu D., Liu Y., Wu K., Zeng Q., Wu J.W. et al.

Nature 491:478-482(2012) · Mapped (1)

Negative control of mast cell degranulation and the anaphylactic response by the phosphatase lipin1.

Shin J., Zhang P., Wang S., Wu J., Guan Z., Zhong X.P.

Eur. J. Immunol. 43:240-248(2013) · Mapped (6)

Down-regulated P53 by siRNA increases Smad4's activity in promoting cell apoptosis in MCF-7 cells.

Wu B., Li W., Qian C., Zhou Z., Xu W., Wu J.

Eur Rev Med Pharmacol Sci 16:1243-1248(2012) · Mapped (34)

Rap1-interacting adapter molecule (RIAM) associates with the plasma membrane via a proximity detector.

Wynne J.P., Wu J., Su W., Mor A., Patsoukis N., Boussiotis V.A., Hubbard S.R., Philips M.R.

J. Cell Biol. 199:317-330(2012) · Mapped (5)

Promoter-associated small double-stranded RNA interacts with heterogeneous nuclear ribonucleoprotein A2/B1 to induce transcriptional activation.

Hu J., Chen Z., Xia D., Wu J., Xu H., Ye Z.Q.

Biochem. J. 447:407-416(2012) · Mapped (7)

Population diversity of rice stripe virus-derived siRNAs in three different hosts and RNAi-based antiviral immunity in Laodelphgax striatellus.

Xu Y., Huang L., Fu S., Wu J., Zhou X.

PLoS ONE 7:e46238-e46238(2012) · UniProtKB (12)

TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis.

Ye L., Kleiner S., Wu J., Sah R., Gupta R.K., Banks A.S., Cohen P., Khandekar M.J., Bostrom P., Mepani R.J. et al.

Cell 151:96-110(2012) · Mapped (5)

Escherichia coli noncoding RNAs can affect gene expression and physiology of Caenorhabditis elegans.

Liu H., Wang X., Wang H.D., Wu J., Ren J., Meng L., Wu Q., Dong H., Wu J., Kao T.Y. et al.

Nat Commun 3:1073-1073(2012) · Mapped (4)

Calpain-1 regulation of matrix metalloproteinase 2 activity in vascular smooth muscle cells facilitates age-associated aortic wall calcification and fibrosis.

Jiang L., Zhang J., Monticone R.E., Telljohann R., Wu J., Wang M., Lakatta E.G.

Hypertension 60:1192-1199(2012) · Mapped (2)

TLR 2 induces vascular smooth muscle cell migration through cAMP response element-binding protein-mediated interleukin-6 production.

Lee G.L., Chang Y.W., Wu J.Y., Wu M.L., Wu K.K., Yet S.F., Kuo C.C.

Arterioscler. Thromb. Vasc. Biol. 32:2751-2760(2012) · Mapped (11)

The collection of NFATc1-dependent transcripts in the osteoclast includes numerous genes non-essential to physiologic bone resorption.

Charles J.F., Coury F., Sulyanto R., Sitara D., Wu J., Brady N., Tsang K., Sigrist K., Tollefsen D.M., He L. et al.

Bone 51:902-912(2012) · Mapped (10)

Surveillance and genome analysis of human bocavirus in patients with respiratory infection in Guangzhou, China.

Xu L., He X., Zhang D.M., Feng F.S., Wang Z., Guan L.L., Wu J.H., Zhou R., Zheng B.J., Yuen K.Y. et al.

PLoS ONE 7:e44876-e44876(2012) · UniProtKB (7)

Progranulin compensates for blocked IGF-1 signaling to promote myotube hypertrophy in C2C12 myoblasts via the PI3K/Akt/mTOR pathway.

Hu S.Y., Tai C.C., Li Y.H., Wu J.L.

FEBS Lett. 586:3485-3492(2012) · Mapped (26)

MiR-136 promotes apoptosis of glioma cells by targeting AEG-1 and Bcl-2.

Yang Y., Wu J., Guan H., Cai J., Fang L., Li J., Li M.

FEBS Lett. 586:3608-3612(2012) · Mapped (5)

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