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1 - 25 of 87 results for author:"Wrana J.L." in Literature citations

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High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGFbeta pathways as fundamental Notch regulators in breast cancer.

Izrailit J., Berman H.K., Datti A., Wrana J.L., Reedijk M.

Proc. Natl. Acad. Sci. U.S.A. 110:1714-1719(2013) · Mapped (14)

C4ST-1/CHST11-controlled chondroitin sulfation interferes with oncogenic HRAS signaling in Costello syndrome.

Kluppel M., Samavarchi-Tehrani P., Liu K., Wrana J.L., Hinek A.

Eur. J. Hum. Genet. 20:870-877(2012) · Mapped (9)

Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation.

Sangwan M., McCurdy S.R., Livne-Bar I., Ahmad M., Wrana J.L., Chen D., Bremner R.

Oncogene 31:5019-5028(2012) · Mapped (13)

Mink1 regulates beta-catenin-independent Wnt signaling via Prickle phosphorylation.

Daulat A.M., Luu O., Sing A., Zhang L., Wrana J.L., McNeill H., Winklbauer R., Angers S.

Mol. Cell. Biol. 32:173-185(2012) · Mapped (16)

Image-based genome-wide siRNA screen identifies selective autophagy factors.

Orvedahl A., Sumpter R. Jr., Xiao G., Ng A., Zou Z., Tang Y., Narimatsu M., Gilpin C., Sun Q., Roth M. et al.

Nature 480:113-117(2011) · Mapped (5)

Structural basis for specificity of TGFbeta family receptor small molecule inhibitors.

Ogunjimi A.A., Zeqiraj E., Ceccarelli D.F., Sicheri F., Wrana J.L., David L.

Cell. Signal. 24:476-483(2012) · Mapped (1)

An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.

Gabut M., Samavarchi-Tehrani P., Wang X., Slobodeniuc V., O'Hanlon D., Sung H.K., Alvarez M., Talukder S., Pan Q., Mazzoni E.O. et al.

Cell 147:132-146(2011) · Mapped (17)

TGF-beta signalling is mediated by two autonomously functioning TbetaRI:TbetaRII pairs.

Huang T., David L., Mendoza V., Yang Y., Villarreal M., De K., Sun L., Fang X., Lopez-Casillas F., Wrana J.L. et al.

EMBO J. 30:1263-1276(2011) · Mapped (17)

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway.

Varelas X., Samavarchi-Tehrani P., Narimatsu M., Weiss A., Cockburn K., Larsen B.G., Rossant J., Wrana J.L.

Dev. Cell 19:831-844(2010) · Mapped (42)

Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity.

Chong P.A., Lin H., Wrana J.L., Forman-Kay J.D.

Proc. Natl. Acad. Sci. U.S.A. 107:18404-18409(2010) · Mapped (2)

Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling.

Gumienny T.L., Macneil L., Zimmerman C.M., Wang H., Chin L., Wrana J.L., Padgett R.W.

PLoS Genet. 6:e1000963-e1000963(2010) · Mapped (8)

The Hippo pathway regulates Wnt/beta-catenin signaling.

Varelas X., Miller B.W., Sopko R., Song S., Gregorieff A., Fellouse F.A., Sakuma R., Pawson T., Hunziker W., McNeill H. et al.

Dev. Cell 18:579-591(2010) · Mapped (41)

Extracellular matrix-induced transforming growth factor-beta receptor signaling dynamics.

Garamszegi N., Garamszegi S.P., Samavarchi-Tehrani P., Walford E., Schneiderbauer M.M., Wrana J.L., Scully S.P.

Oncogene 29:2368-2380(2010) · Mapped (9)

Identification and characterization of TGFbeta-dependent and -independent cis-regulatory modules in the C4ST-1/CHST11 locus.

Willis C.M., Wrana J.L., Kluppel M.

Genet. Mol. Res. 8:1331-1343(2009) · Mapped (10)

A role for the TGFbeta-Par6 polarity pathway in breast cancer progression.

Viloria-Petit A.M., David L., Jia J.Y., Erdemir T., Bane A.L., Pinnaduwage D., Roncari L., Narimatsu M., Bose R., Moffat J. et al.

Proc. Natl. Acad. Sci. U.S.A. 106:14028-14033(2009) · Mapped (13)

Regulation of planar cell polarity by Smurf ubiquitin ligases.

Narimatsu M., Bose R., Pye M., Zhang L., Miller B., Ching P., Sakuma R., Luga V., Roncari L., Attisano L. et al.

Cell 137:295-307(2009) · Mapped (40)

The extracellular domain of the TGFbeta type II receptor regulates membrane raft partitioning.

Luga V., McLean S., Le Roy C., O'Connor-McCourt M., Wrana J.L., Di Guglielmo G.M.

Biochem. J. 421:119-131(2009) · Mapped (5)

UNC-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways.

MacNeil L.T., Hardy W.R., Pawson T., Wrana J.L., Culotti J.G.

Nat. Neurosci. 12:150-155(2009) · Mapped (3)

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.

Varelas X., Sakuma R., Samavarchi-Tehrani P., Peerani R., Rao B.M., Dembowy J., Yaffe M.B., Zandstra P.W., Wrana J.L.

Nat. Cell Biol. 10:837-848(2008) · UniProtKB (5) · Mapped (9)

Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development.

Silvestri C., Narimatsu M., von Both I., Liu Y., Tan N.B., Izzi L., McCaffery P., Wrana J.L., Attisano L.

Dev. Cell 14:411-423(2008) · Mapped (92)

Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding.

Groppe J., Hinck C.S., Samavarchi-Tehrani P., Zubieta C., Schuermann J.P., Taylor A.B., Schwarz P.M., Wrana J.L., Hinck A.P.

Mol. Cell 29:157-168(2008) · UniProtKB (2) · Mapped (15)

The slit receptor EVA-1 coactivates a SAX-3/Robo mediated guidance signal in C. elegans.

Fujisawa K., Wrana J.L., Culotti J.G.

Science 317:1934-1938(2007) · UniProtKB (1) · Mapped (4)

A chemical biology screen identifies glucocorticoids that regulate c-maf expression by increasing its proteasomal degradation through up-regulation of ubiquitin.

Mao X., Stewart A.K., Hurren R., Datti A., Zhu X., Zhu Y., Shi C., Lee K., Tiedemann R., Eberhard Y. et al.

Blood 110:4047-4054(2007) · UniProtKB (1)

Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain.

Wiesner S., Ogunjimi A.A., Wang H.R., Rotin D., Sicheri F., Wrana J.L., Forman-Kay J.D.

Cell 130:651-662(2007) · UniProtKB (2) · Mapped (1)

Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development.

Izzi L., Silvestri C., von Both I., Labbe E., Zakin L., Wrana J.L., Attisano L.

EMBO J. 26:3132-3143(2007) · UniProtKB (1) · Mapped (33)

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