| Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival. Robert F., Mills J.R., Agenor A., Wang D., DiMarco S., Cencic R., Tremblay M.L., Gallouzi I.E., Hekimi S., Wing S.S. et al.
Cancer Res. 72:747-756(2012) · Mapped (9) |
| Ataxin-3 deubiquitination is coupled to Parkin ubiquitination via E2 ubiquitin-conjugating enzyme. Durcan T.M., Kontogiannea M., Bedard N., Wing S.S., Fon E.A.
J. Biol. Chem. 287:531-541(2012) · Mapped (20) |
| Mice lacking the USP2 deubiquitinating enzyme have severe male subfertility associated with defects in fertilization and sperm motility. Bedard N., Yang Y., Gregory M., Cyr D.G., Suzuki J., Yu X., Chian R.C., Hermo L., O'Flaherty C., Smith C.E. et al.
Biol. Reprod. 85:594-604(2011) · Mapped (3) |
| Identification of distinctive patterns of USP19-mediated growth regulation in normal and malignant cells. Lu Y., Bedard N., Chevalier S., Wing S.S.
PLoS ONE 6:e15936-e15936(2011) · Mapped (14) |
| Mechanisms involved in 3',5'-cyclic adenosine monophosphate-mediated inhibition of the ubiquitin-proteasome system in skeletal muscle. Goncalves D.A., Lira E.C., Baviera A.M., Cao P., Zanon N.M., Arany Z., Bedard N., Tanksale P., Wing S.S., Lecker S.H. et al.
Endocrinology 150:5395-5404(2009) · Mapped (11) |
| USP19-deubiquitinating enzyme regulates levels of major myofibrillar proteins in L6 muscle cells. Sundaram P., Pang Z., Miao M., Yu L., Wing S.S.
Am. J. Physiol. 297:E1283-E1290(2009) · UniProtKB (1) |
| USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1. Lu Y., Adegoke O.A.J., Nepveu A., Nakayama K.I., Bedard N., Cheng D., Peng J., Wing S.S.
Mol. Cell. Biol. 29:547-558(2009) · UniProtKB (2) · Mapped (3) |
| Regulated expression of the ubiquitin protein ligase, E3(Histone)/LASU1/Mule/ARF-BP1/HUWE1, during spermatogenesis. Liu Z., Miao D., Xia Q., Hermo L., Wing S.S.
Dev. Dyn. 236:2889-2898(2007) · UniProtKB (2) · Mapped (8) |
| A new method of purification of proteasome substrates reveals polyubiquitination of 20 S proteasome subunits. Ventadour S., Jarzaguet M., Wing S.S., Chambon C., Combaret L., Bechet D., Attaix D., Taillandier D.
J. Biol. Chem. 282:5302-5309(2007) · Mapped (2) |
| Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2. Yoshida M., Yoshida K., Kozlov G., Lim N.S., De Crescenzo G., Pang Z., Berlanga J.J., Kahvejian A., Gehring K., Wing S.S. et al.
EMBO J. 25:1934-1944(2006) · Mapped (6) |
| BH3-ligand regulates access of MCL-1 to its E3 ligase. Warr M.R., Acoca S., Liu Z., Germain M., Watson M., Blanchette M., Wing S.S., Shore G.C.
FEBS Lett. 579:5603-5608(2005) · Mapped (17) |
| Mice lacking the UBC4-testis gene have a delay in postnatal testis development but normal spermatogenesis and fertility. Bedard N., Hingamp P., Pang Z., Karaplis A., Morales C., Trasler J., Cyr D., Gagnon C., Wing S.S.
Mol. Cell. Biol. 25:6346-6354(2005) · UniProtKB (1) · Mapped (2) |
| Characterization of E3Histone, a novel testis ubiquitin protein ligase which ubiquitinates histones. Liu Z., Oughtred R., Wing S.S.
Mol. Cell. Biol. 25:2819-2831(2005) · UniProtKB (2) |
| USP19 is a ubiquitin-specific protease regulated in rat skeletal muscle during catabolic states. Combaret L., Adegoke O.A.J., Bedard N., Baracos V., Attaix D., Wing S.S.
Am. J. Physiol. 288:E693-E700(2005) · UniProtKB (1) |
| Characterization of rat100, a 300-kilodalton ubiquitin-protein ligase induced in germ cells of the rat testis and similar to the Drosophila hyperplastic discs gene. Oughtred R., Bedard N., Adegoke O.A.J., Morales C.R., Trasler J., Rajapurohitam V., Wing S.S.
Endocrinology 143:3740-3747(2002) · UniProtKB (1) · Mapped (1) |
| Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity. Beitel L.K., Elhaji Y.A., Lumbroso R., Wing S.S., Panet-Raymond V., Gottlieb B., Pinsky L., Trifiro M.A.
J. Mol. Endocrinol. 29:41-60(2002) · Mapped (12) |
| Ubiquitin-conjugating enzyme E214k/HR6B is dispensable for increased protein catabolism in muscle of fasted mice. Adegoke O.A., Bedard N., Roest H.P., Wing S.S.
Am. J. Physiol. Endocrinol. Metab. 283:E482-9(2002) · Mapped (2) |
| Control of ubiquitination of proteins in rat tissues by ubiquitin conjugating enzymes and isopeptidases. Rajapurohitam V., Bedard N., Wing S.S.
Am. J. Physiol. Endocrinol. Metab. 282:E739-45(2002) · Mapped (3) |
| Divergent N-terminal sequences target an inducible testis deubiquitinating enzyme to distinct subcellular structures. Lin H., Keriel A., Morales C.R., Bedard N., Zhao Q., Hingamp P., Lefrancois S., Combaret L., Wing S.S.
Mol. Cell. Biol. 20:6568-6578(2000) · UniProtKB (1) |
| The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase. Joazeiro C.A., Wing S.S., Huang H.-K., Leverson J.D., Hunter T., Liu Y.-C.
Science 286:309-312(1999) · UniProtKB (1) |
| Identification of rabbit reticulocyte E217K as a UBC7 homologue and functional characterization of its core domain loop. Lin H., Wing S.S.
J. Biol. Chem. 274:14685-14691(1999) · UniProtKB (1) · Mapped (1) |
| Identification of amino acid residues in a class I ubiquitin-conjugating enzyme involved in determining specificity of conjugation of ubiquitin to proteins. Oughtred R., Bedard N., Vrielink A., Wing S.S.
J. Biol. Chem. 273:18435-18442(1998) · Mapped (2) |
| A novel rat homolog of the Saccharomyces cerevisiae ubiquitin-conjugating enzymes UBC4 and UBC5 with distinct biochemical features is induced during spermatogenesis. Wing S.S., Bedard N., Morales C., Hingamp P., Trasler J.
Mol. Cell. Biol. 16:4064-4072(1996) · UniProtKB (1) · Mapped (2) |
| 14-kDa ubiquitin-conjugating enzyme: structure of the rat gene and regulation upon fasting and by insulin. Wing S.S., Banville D.
Am. J. Physiol. 267:E39-E48(1994) · UniProtKB (1) |
| Molecular cloning, expression and characterization of a ubiquitin conjugation enzyme (E2(17)kB) highly expressed in rat testis. Wing S.S., Jain P.
Biochem. J. 305:125-132(1995) · UniProtKB (2) · Mapped (5) |
