| Spliceosome structure and function. Will C.L., Luhrmann R.
Cold Spring Harb Perspect Biol 3:0-0(2011) · Mapped (81) |
| HSPC117 is the essential subunit of a human tRNA splicing ligase complex. Popow J., Englert M., Weitzer S., Schleiffer A., Mierzwa B., Mechtler K., Trowitzsch S., Will C.L., Luhrmann R., Soll D. et al.
Science 331:760-764(2011) · UniProtKB (5) · Mapped (3) |
| Molecular architecture of the human Prp19/CDC5L complex. Grote M., Wolf E., Will C.L., Lemm I., Agafonov D.E., Schomburg A., Fischle W., Urlaub H., Luhrmann R.
Mol. Cell. Biol. 30:2105-2119(2010) · UniProtKB (7) |
| Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation. Schneider M., Hsiao H.H., Will C.L., Giet R., Urlaub H., Luhrmann R.
Nat. Struct. Mol. Biol. 17:216-221(2010) · Mapped (6) |
| The spliceosome: design principles of a dynamic RNP machine. Wahl M.C., Will C.L., Luhrmann R.
Cell 136:701-718(2009) · Mapped (81) |
| Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Herold N., Will C.L., Wolf E., Kastner B., Urlaub H., Luhrmann R.
Mol. Cell. Biol. 29:281-301(2009) · Mapped (268) |
| Minor spliceosome components are predominantly localized in the nucleus. Pessa H.K., Will C.L., Meng X., Schneider C., Watkins N.J., Perala N., Nymark M., Turunen J.J., Luhrmann R., Frilander M.J.
Proc. Natl. Acad. Sci. U.S.A. 105:8655-8660(2008) · Mapped (42) |
| The U11-48K protein contacts the 5' splice site of U12-type introns and the U11-59K protein. Turunen J.J., Will C.L., Grote M., Luhrmann R., Frilander M.J.
Mol. Cell. Biol. 28:3548-3560(2008) · Mapped (2) |
| Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. Behzadnia N., Golas M.M., Hartmuth K., Sander B., Kastner B., Deckert J., Dube P., Will C.L., Urlaub H., Stark H. et al.
EMBO J. 26:1737-1748(2007) · UniProtKB (1) · Mapped (100) |
| Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment. Merz C., Urlaub H., Will C.L., Luhrmann R.
RNA 13:116-128(2007) · UniProtKB (2) |
| The U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11-59K protein. Benecke H., Luehrmann R., Will C.L.
EMBO J. 24:3057-3069(2005) · UniProtKB (2) · Mapped (1) |
| Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila. Schneider C., Will C.L., Brosius J., Frilander M.J., Luhrmann R.
Proc. Natl. Acad. Sci. U.S.A. 101:9584-9589(2004) · Mapped (52) |
| A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing. Makarova O.V., Makarov E.M., Urlaub H., Will C.L., Gentzel M., Wilm M., Luhrmann R.
EMBO J. 23:2381-2391(2004) · Mapped (1) |
| The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. Will C.L., Schneider C., Hossbach M., Urlaub H., Rauhut R., Elbashir S., Tuschl T., Luehrmann R.
RNA 10:929-941(2004) · UniProtKB (25) |
| Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing. Pillai R.S., Grimmler M., Meister G., Will C.L., Luehrmann R., Fischer U., Schuemperli D.
Genes Dev. 17:2321-2333(2003) · UniProtKB (6) · Mapped (2) |
| Molecular architecture of the multiprotein splicing factor SF3b. Golas M.M., Sander B., Will C.L., Luhrmann R., Stark H.
Science 300:980-984(2003) · UniProtKB (7) · Mapped (12) |
| Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method. Hartmuth K., Urlaub H., Vornlocher H.P., Will C.L., Gentzel M., Wilm M., Luhrmann R.
Proc. Natl. Acad. Sci. U.S.A. 99:16719-16724(2002) · Mapped (92) |
| Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. Will C.L., Urlaub H., Achsel T., Gentzel M., Wilm M., Luehrmann R.
EMBO J. 21:4978-4988(2002) · UniProtKB (10) · Mapped (9) |
| Human U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions. Schneider C., Will C.L., Makarova O.V., Makarov E.M., Luehrmann R.
Mol. Cell. Biol. 22:3219-3229(2002) · UniProtKB (1) |
| Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein. Pillai R.S., Will C.L., Luehrmann R., Schuemperli D., Mueller B.
EMBO J. 20:5470-5479(2001) · UniProtKB (7) · Mapped (5) |
| A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site. Will C.L., Schneider C., MacMillan A.M., Katopodis N.F., Neubauer G., Wilm M., Luehrmann R., Query C.C.
EMBO J. 20:4536-4546(2001) · UniProtKB (1) · Mapped (1) |
| Molecular biology. RNP remodeling with DExH/D boxes. Will C.L., Luhrmann R.
Science 291:1916-1917(2001) · Mapped (5) |
| The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p. Teigelkamp S., Mundt C., Achsel T., Will C.L., Luehrmann R.
RNA 3:1313-1326(1997) · UniProtKB (2) · Mapped (1) |
| The human U4/U6 snRNP contains 60 and 90kD proteins that are structurally homologous to the yeast splicing factors Prp4p and Prp3p. Lauber J., Plessel G., Prehn S., Will C.L., Fabrizio P., Groning K., Lane W.S., Luehrmann R.
RNA 3:926-941(1997) · UniProtKB (1) · Mapped (2) |
| Protein functions in pre-mRNA splicing. Will C.L., Luhrmann R.
Curr. Opin. Cell Biol. 9:320-328(1997) · Mapped (4) |
