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Structure of unliganded HSV gD reveals a mechanism for receptor-mediated activation of virus entry.

Krummenacher C., Supekar V.M., Whitbeck J.C., Lazear E., Connolly S.A., Eisenberg R.J., Cohen G.H., Wiley D.C., Carfi A.

EMBO J. 24:4144-4153(2005) · UniProtKB (1)

Identification of domain boundaries within the N-termini of TAP1 and TAP2 and their importance in tapasin binding and tapasin-mediated increase in peptide loading of MHC class I.

Procko E., Raghuraman G., Wiley D.C., Raghavan M., Gaudet R.

Immunol. Cell Biol. 83:475-482(2005) · Mapped (25)

Structure of an unliganded simian immunodeficiency virus gp120 core.

Chen B., Vogan E.M., Gong H., Skehel J.J., Wiley D.C., Harrison S.C.

Nature 433:834-841(2005) · UniProtKB (1) · Mapped (1)

Determining the structure of an unliganded and fully glycosylated SIV gp120 envelope glycoprotein.

Chen B., Vogan E.M., Gong H., Skehel J.J., Wiley D.C., Harrison S.C.

Structure 13:197-211(2005) · Mapped (2)

Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment.

Arnett K.L., Harrison S.C., Wiley D.C.

Proc. Natl. Acad. Sci. U.S.A. 101:16268-16273(2004) · UniProtKB (2) · Mapped (60)

The structure and receptor binding properties of the 1918 influenza hemagglutinin.

Gamblin S.J., Haire L.F., Russell R.J., Stevens D.J., Xiao B., Ha Y., Vasisht N., Steinhauer D.A., Daniels R.S., Elliot A. et al.

Science 303:1838-1842(2004) · UniProtKB (3) · Mapped (3)

X-ray structure of the hemagglutinin of a potential H3 avian progenitor of the 1968 Hong Kong pandemic influenza virus.

Ha Y., Stevens D.J., Skehel J.J., Wiley D.C.

Virology 309:209-218(2003) · UniProtKB (1)

Crystallization and preliminary diffraction studies of the ectodomain of the envelope glycoprotein D from herpes simplex virus 1 alone and in complex with the ectodomain of the human receptor HveA.

Carfi A., Gong H., Lou H., Willis S.H., Cohen G.H., Eisenberg R.J., Wiley D.C.

Acta Crystallogr. D Biol. Crystallogr. 58:836-838(2002) · Mapped (6)

Structure of a complex of the human alpha/beta T cell receptor (TCR) HA1.7, influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRA*0101 and DRB1*0401): insight into TCR cross-restriction and alloreactivity.

Hennecke J., Wiley D.C.

J. Exp. Med. 195:571-581(2002) · Mapped (5)

H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes.

Ha Y., Stevens D.J., Skehel J.J., Wiley D.C.

EMBO J. 21:865-875(2002) · UniProtKB (2) · Mapped (2)

X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs.

Ha Y., Stevens D.J., Skehel J.J., Wiley D.C.

Proc. Natl. Acad. Sci. U.S.A. 98:11181-11186(2001) · UniProtKB (2)

Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes.

Sliz P., Michielin O., Cerottini J.C., Luescher I., Romero P., Karplus M., Wiley D.C.

J. Immunol. 167:3276-3284(2001) · Mapped (2)

Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing.

Gaudet R., Wiley D.C.

EMBO J. 20:4964-4972(2001) · UniProtKB (1)

Herpes simplex virus glycoprotein D bound to the human receptor HveA.

Carfi A., Willis S.H., Whitbeck J.C., Krummenacher C., Cohen G.H., Eisenberg R.J., Wiley D.C.

Mol. Cell 8:169-179(2001) · UniProtKB (2)

Antigen presentation subverted: structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2.

Gewurz B.E., Gaudet R., Tortorella D., Wang E.W., Ploegh H.L., Wiley D.C.

Proc. Natl. Acad. Sci. U.S.A. 98:6794-6799(2001) · UniProtKB (1) · Mapped (2)

Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes.

Lee K.H., Wucherpfennig K.W., Wiley D.C.

Nat. Immunol. 2:501-507(2001) · UniProtKB (2)

Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex.

Fan Q.R., Long E.O., Wiley D.C.

Nat. Immunol. 2:452-460(2001) · Mapped (3)

Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1.

Hennecke J., Carfi A., Wiley D.C.

EMBO J. 19:5611-5624(2000) · Mapped (4)

The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core.

Zhou G., Ferrer M., Chopra R., Kapoor T.M., Strassmaier T., Weissenhorn W., Skehel J.J., Oprian D., Schreiber S.L., Harrison S.C. et al.

Bioorg. Med. Chem. 8:2219-2227(2000) · UniProtKB (1) · Mapped (1)

The structure and stability of an HLA-A*0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site.

Khan A.R., Baker B.M., Ghosh P., Biddison W.E., Wiley D.C.

J. Immunol. 164:6398-6405(2000) · Mapped (2)

Structure of a soluble secreted chemokine inhibitor vCCI (p35) from cowpox virus.

Carfi A., Smith C.A., Smolak P.J., McGrew J., Wiley D.C.

Proc. Natl. Acad. Sci. U.S.A. 96:12379-12383(1999) · UniProtKB (1)

Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.

Ding Y.H., Baker B.M., Garboczi D.N., Biddison W.E., Wiley D.C.

Immunity 11:45-56(1999) · Mapped (3)

N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coil.

Chen J., Skehel J.J., Wiley D.C.

Proc. Natl. Acad. Sci. U.S.A. 96:8967-8972(1999) · Mapped (1)

Structure of human histocompatibility leukocyte antigen (HLA)-Cw4, a ligand for the KIR2D natural killer cell inhibitory receptor.

Fan Q.R., Wiley D.C.

J. Exp. Med. 190:113-123(1999) · Mapped (2)

Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain.

Weissenhorn W., Carfi A., Lee K.H., Skehel J.J., Wiley D.C.

Mol. Cell 2:605-616(1998) · UniProtKB (1)

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