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Specific tyrosine phosphorylations mediate signal-dependent stimulation of SHIP2 inositol phosphatase activity, while the SH2 domain confers an inhibitory effect to maintain the basal activity.

Prasad N.K., Werner M.E., Decker S.J.

Biochemistry 48:6285-6287(2009) · Mapped (1)

Spatial allelic imbalance of BCL2 genes and chromosome 18 territories in nonneoplastic and neoplastic cervical squamous epithelium.

Wiech T., Stein S., Lachenmaier V., Schmitt E., Schwarz-Finsterle J., Wiech E., Hildenbrand G., Werner M., Hausmann M.

Eur. Biophys. J. 38:793-806(2009) · Mapped (4)

The natriuretic peptide/guanylyl cyclase--a system functions as a stress-responsive regulator of angiogenesis in mice.

Kuhn M., Volker K., Schwarz K., Carbajo-Lozoya J., Flogel U., Jacoby C., Stypmann J., van Eickels M., Gambaryan S., Hartmann M. et al.

J. Clin. Invest. 119:2019-2030(2009) · Mapped (8)

CpG-island methylation of the ER promoter in colorectal cancer: analysis of micrometastases in lymph nodes from UICC stage I and II patients.

Harder J., Engelstaedter V., Usadel H., Lassmann S., Werner M., Baier P., Otto F., Varbanova M., Schaeffner E., Olschewski M. et al.

Br. J. Cancer 100:360-365(2009) · Mapped (53)

Role of GluR1 in activity-dependent motor system development.

Zhang L., Schessl J., Werner M., Bonnemann C., Xiong G., Mojsilovic-Petrovic J., Zhou W., Cohen A., Seeburg P., Misawa H. et al.

J. Neurosci. 28:9953-9968(2008) · Mapped (7)

Transcriptional upregulation of p21/WAF/Cip1 in myeloid leukemic blasts expressing AML1-ETO.

Berg T., Fliegauf M., Burger J., Staege M.S., Liu S., Martinez N., Heidenreich O., Burdach S., Haferlach T., Werner M.H. et al.

Haematologica 93:1728-1733(2008) · Mapped (9)

Mediator-dependent recruitment of TFIIH modules in preinitiation complex.

Esnault C., Ghavi-Helm Y., Brun S., Soutourina J., Van Berkum N., Boschiero C., Holstege F., Werner M.

Mol. Cell 31:337-346(2008) · Mapped (13)

Microarray comparative genomic hybridization analysis of tubular breast carcinoma shows recurrent loss of the CDH13 locus on 16q.

Riener M.O., Nikolopoulos E., Herr A., Wild P.J., Hausmann M., Wiech T., Orlowska-Volk M., Lassmann S., Walch A., Werner M.

Hum. Pathol. 39:1621-1629(2008) · Mapped (8)

Genome-wide location analysis reveals a role of TFIIS in RNA polymerase III transcription.

Ghavi-Helm Y., Michaut M., Acker J., Aude J.C., Thuriaux P., Werner M., Soutourina J.

Genes Dev. 22:1934-1947(2008) · Mapped (7)

The effect of selective inhibition of inducible nitric oxide synthase on cytochrome P450 after liver transplantation in a rat model.

Matevossian E., Novotny A., Knebel C., Brill T., Werner M., Sinicina I., Kriner M., Stangl M., Thorban S., Huser N.

Transplant. Proc. 40:983-985(2008) · Mapped (1)

Hypercontractility and impaired sildenafil relaxations in the BKCa channel deletion model of erectile dysfunction.

Werner M.E., Meredith A.L., Aldrich R.W., Nelson M.T.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 295:R181-8(2008) · Mapped (9)

Cyclin D1 expression is induced by viral BARF1 and is overexpressed in EBV-associated gastric cancer.

Wiech T., Nikolopoulos E., Lassman S., Heidt T., Schopflin A., Sarbia M., Werner M., Shimizu Y., Sakka E., Ooka T. et al.

Virchows Arch. 452:621-627(2008) · Mapped (6)

Aurora-a is a predictive marker for stage III epithelial ovarian cancers.

Lassmann S., Shen Y., Jutting U., Whiele P., Walch A., Gitsch G., Hasenburg A., Werner M.

Verh Dtsch Ges Pathol 91:225-232(2007) · Mapped (6)

Comparative analysis of the pharmacology of GluR1 in complex with transmembrane AMPA receptor regulatory proteins gamma2, gamma3, gamma4, and gamma8.

Kott S., Sager C., Tapken D., Werner M., Hollmann M.

Neuroscience 158:78-88(2009) · Mapped (1)

Two RNA polymerase I subunits control the binding and release of Rrn3 during transcription.

Beckouet F., Labarre-Mariotte S., Albert B., Imazawa Y., Werner M., Gadal O., Nogi Y., Thuriaux P.

Mol. Cell. Biol. 28:1596-1605(2008) · Mapped (11)

Tumor-derived CCL5 does not contribute to breast cancer progression.

Jayasinghe M.M., Golden J.M., Nair P., O'Donnell C.M., Werner M.T., Kurt R.A.

Breast Cancer Res. Treat. 111:511-521(2008) · Mapped (2)

Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination in Sepp-knockout mice.

Renko K., Werner M., Renner-Muller I., Cooper T.G., Yeung C.H., Hollenbach B., Scharpf M., Kohrle J., Schomburg L., Schweizer U.

Biochem. J. 409:741-749(2008) · Mapped (2)

TFIIS elongation factor and Mediator act in conjunction during transcription initiation in vivo.

Guglielmi B., Soutourina J., Esnault C., Werner M.

Proc. Natl. Acad. Sci. U.S.A. 104:16062-16067(2007) · Mapped (6)

The transmembrane AMPA receptor regulatory protein gamma 4 is a more effective modulator of AMPA receptor function than stargazin (gamma 2).

Korber C., Werner M., Kott S., Ma Z.L., Hollmann M.

J. Neurosci. 27:8442-8447(2007) · Mapped (1)

Astral signals spatially bias cortical myosin recruitment to break symmetry and promote cytokinesis.

Werner M., Munro E., Glotzer M.

Curr. Biol. 17:1286-1297(2007) · Mapped (18)

Predictive value of Aurora-A/STK15 expression for late stage epithelial ovarian cancer patients treated by adjuvant chemotherapy.

Lassmann S., Shen Y., Jutting U., Wiehle P., Walch A., Gitsch G., Hasenburg A., Werner M.

Clin. Cancer Res. 13:4083-4091(2007) · Mapped (6)

A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription.

Wei Y., Liu S., Lausen J., Woodrell C., Cho S., Biris N., Kobayashi N., Wei Y., Yokoyama S., Werner M.H.

Nat. Struct. Mol. Biol. 14:653-661(2007) · UniProtKB (1) · Mapped (1)

Stargazin interaction with alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors is critically dependent on the amino acid at the narrow constriction of the ion channel.

Korber C., Werner M., Hoffmann J., Sager C., Tietze M., Schmid S.M., Kott S., Hollmann M.

J. Biol. Chem. 282:18758-18766(2007) · Mapped (10)

Distinct roles for Mediator Cdk8 module subunits in Drosophila development.

Loncle N., Boube M., Joulia L., Boschiero C., Werner M., Cribbs D.L., Bourbon H.-M.

EMBO J. 26:1045-1054(2007) · UniProtKB (4) · Mapped (25)

IRAG mediates NO/cGMP-dependent inhibition of platelet aggregation and thrombus formation.

Antl M., von Bruehl M.-L., Eiglsperger C., Werner M., Konrad I., Kocher T., Wilm M., Hofmann F., Massberg S., Schlossmann J.

Blood 109:552-559(2007) · UniProtKB (6) · Mapped (5)

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