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Recurring mutations found by sequencing an acute myeloid leukemia genome.

Mardis E.R., Ding L., Dooling D.J., Larson D.E., McLellan M.D., Chen K., Koboldt D.C., Fulton R.S., Delehaunty K.D., McGrath S.D. et al.

N. Engl. J. Med. 361:1058-1066(2009) · Mapped (10)

Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer.

Graveel C.R., DeGroot J.D., Su Y., Koeman J., Dykema K., Leung S., Snider J., Davies S.R., Swiatek P.J., Cottingham S. et al.

Proc. Natl. Acad. Sci. U.S.A. 106:12909-12914(2009) · Mapped (32)

SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage.

Garcia-Caballero A., Rasmussen J.E., Gaillard E., Watson M.J., Olsen J.C., Donaldson S.H., Stutts M.J., Tarran R.

Proc. Natl. Acad. Sci. U.S.A. 106:11412-11417(2009) · Mapped (8)

Decreased neuronal CD200 expression in IL-4-deficient mice results in increased neuroinflammation in response to lipopolysaccharide.

Lyons A., McQuillan K., Deighan B.F., O'Reilly J.A., Downer E.J., Murphy A.C., Watson M., Piazza A., O'Connell F., Griffin R. et al.

Brain Behav. Immun. 23:1020-1027(2009) · Mapped (7)

Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer.

Cheang M.C., Chia S.K., Voduc D., Gao D., Leung S., Snider J., Watson M., Davies S., Bernard P.S., Parker J.S. et al.

J. Natl. Cancer Inst. 101:736-750(2009) · Mapped (76)

In vitro and in vivo effects of adiponectin on bone.

Williams G.A., Wang Y., Callon K.E., Watson M., Lin J.M., Lam J.B., Costa J.L., Orpe A., Broom N., Naot D. et al.

Endocrinology 150:3603-3610(2009) · Mapped (3)

Actions of fibroblast growth factor-8 in bone cells in vitro.

Lin J.M., Callon K.E., Lin J.S., Watson M., Empson V., Tong P.C., Grey A., Naot D., Green C.R., Reid I.R. et al.

Am. J. Physiol. Endocrinol. Metab. 297:E142-50(2009) · Mapped (4)

Voltage-independent calcium channels mediate lipopolysaccharide-induced hyporeactivity to endothelin-1 in the rat aorta.

El-Awady M.S., Smirnov S.V., Watson M.L.

Am. J. Physiol. Heart Circ. Physiol. 296:H1408-15(2009) · Mapped (1)

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome.

Ley T.J., Mardis E.R., Ding L., Fulton B., McLellan M.D., Chen K., Dooling D., Dunford-Shore B.H., McGrath S., Hickenbotham M. et al.

Nature 456:66-72(2008) · UniProtKB (36)

Copy-number analysis of topoisomerase and thymidylate synthase genes in frozen and FFPE DNAs of colorectal cancers.

Yu J., Miller R., Zhang W., Sharma M., Holtschlag V., Watson M.A., McLeod H.L.

Pharmacogenomics 9:1459-1466(2008) · Mapped (11)

Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity.

Chao E.Y., Caravella J.A., Watson M.A., Campobasso N., Ghisletti S., Billin A.N., Galardi C., Wang P., Laffitte B.A., Iannone M.A. et al.

J. Med. Chem. 51:5758-5765(2008) · Mapped (1)

Correlating EGFR expression with receptor-binding properties and internalization of 64Cu-DOTA-cetuximab in 5 cervical cancer cell lines.

Eiblmaier M., Meyer L.A., Watson M.A., Fracasso P.M., Pike L.J., Anderson C.J.

J. Nucl. Med. 49:1472-1479(2008) · Mapped (15)

A drosophila model for amyotrophic lateral sclerosis reveals motor neuron damage by human SOD1.

Watson M.R., Lagow R.D., Xu K., Zhang B., Bonini N.M.

J. Biol. Chem. 283:24972-24981(2008) · Mapped (1)

Comparative genome analysis of Salmonella enteritidis PT4 and Salmonella gallinarum 287/91 provides insights into evolutionary and host adaptation pathways.

Thomson N.R., Clayton D.J., Windhorst D., Vernikos G., Davidson S., Churcher C., Quail M.A., Stevens M., Jones M.A., Watson M. et al.

Genome Res. 18:1624-1637(2008) · UniProtKB (8,151)

Genetic determinants in the metabolism of bladder carcinogens in relation to risk of bladder cancer.

Yuan J.M., Chan K.K., Coetzee G.A., Castelao J.E., Watson M.A., Bell D.A., Wang R., Yu M.C.

Carcinogenesis 29:1386-1393(2008) · Mapped (34)

Distal airways in mice exposed to cigarette smoke: Nrf2-regulated genes are increased in Clara cells.

Adair-Kirk T.L., Atkinson J.J., Griffin G.L., Watson M.A., Kelley D.G., DeMello D., Senior R.M., Betsuyaku T.

Am. J. Respir. Cell Mol. Biol. 39:400-411(2008) · Mapped (2)

High-resolution, dual-platform aCGH analysis reveals frequent HIPK2 amplification and increased expression in pilocytic astrocytomas.

Deshmukh H., Yeh T.H., Yu J., Sharma M.K., Perry A., Leonard J.R., Watson M.A., Gutmann D.H., Nagarajan R.

Oncogene 27:4745-4751(2008) · Mapped (3)

IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8.

Costelloe C., Watson M., Murphy A., McQuillan K., Loscher C., Armstrong M.E., Garlanda C., Mantovani A., O'Neill L.A., Mills K.H. et al.

J. Neurochem. 105:1960-1969(2008) · Mapped (4)

NF-kappaB is a critical regulator of the survival of rodent and human hepatic myofibroblasts.

Watson M.R., Wallace K., Gieling R.G., Manas D.M., Jaffray E., Hay R.T., Mann D.A., Oakley F.

J. Hepatol. 48:589-597(2008) · Mapped (8)

Interleukin 13 increases contractility of murine tracheal smooth muscle by a phosphoinositide 3-kinase p110delta-dependent mechanism.

Farghaly H.S., Blagbrough I.S., Medina-Tato D.A., Watson M.L.

Mol. Pharmacol. 73:1530-1537(2008) · Mapped (15)

Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia.

Tomasson M.H., Xiang Z., Walgren R., Zhao Y., Kasai Y., Miner T., Ries R.E., Lubman O., Fremont D.H., McLellan M.D. et al.

Blood 111:4797-4808(2008) · Mapped (41)

Identification of somatic JAK1 mutations in patients with acute myeloid leukemia.

Xiang Z., Zhao Y., Mitaksov V., Fremont D.H., Kasai Y., Molitoris A., Ries R.E., Miner T.L., McLellan M.D., DiPersio J.F. et al.

Blood 111:4809-4812(2008) · Mapped (5)

Meta-analysis of the association of the Taq1A polymorphism with the risk of alcohol dependency: a HuGE gene-disease association review.

Smith L., Watson M., Gates S., Ball D., Foxcroft D.

Am. J. Epidemiol. 167:125-138(2008) · Mapped (4)

Mapping intramolecular interactions between domains in HMGB1 using a tail-truncation approach.

Watson M., Stott K., Thomas J.O.

J. Mol. Biol. 374:1286-1297(2007) · Mapped (1)

Upregulation of protein S by progestins.

Hughes Q., Watson M., Cole V., Sayer M., Baker R., Staton J.

J. Thromb. Haemost. 5:2243-2249(2007) · Mapped (37)

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