1 - 25 of 64 results for author:"Waterfield M.D." in Literature citations
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| A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding. Jefferies H.B., Cooke F.T., Jat P., Boucheron C., Koizumi T., Hayakawa M., Kaizawa H., Ohishi T., Workman P., Waterfield M.D. et al. EMBO Rep. 9:164-170(2008) · Mapped (1) |
| Dynamic cofilin phosphorylation in the control of lamellipodial actin homeostasis. Jovceva E., Larsen M.R., Waterfield M.D., Baum B., Timms J.F. J. Cell. Sci. 120:1888-1897(2007) · Mapped (31) |
| Structural and membrane binding analysis of the Phox homology domain of phosphoinositide 3-kinase-C2alpha. Stahelin R.V., Karathanassis D., Bruzik K.S., Waterfield M.D., Bravo J., Williams R.L., Cho W. J. Biol. Chem. 281:39396-39406(2006) · UniProtKB (1) · Mapped (3) |
| Phosphoinositide 3-Kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms. Katso R.M., Pardo O.E., Palamidessi A., Franz C.M., Marinov M., De Laurentiis A., Downward J., Scita G., Ridley A.J., Waterfield M.D. et al. Mol. Biol. Cell 17:3729-3744(2006) · Mapped (8) |
| Targeted expression of the class II phosphoinositide 3-kinase in Drosophila melanogaster reveals lipid kinase-dependent effects on patterning and interactions with receptor signaling pathways. MacDougall L.K., Gagou M.E., Leevers S.J., Hafen E., Waterfield M.D. Mol. Cell. Biol. 24:796-808(2004) · Mapped (280) |
| Two distinct phosphoinositide 3-kinases mediate polypeptide growth factor-stimulated PKB activation. Arcaro A., Khanzada U.K., Vanhaesebroeck B., Tetley T.D., Waterfield M.D., Seckl M.J. EMBO J. 21:5097-5108(2002) · Mapped (8) |
| Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice. Okkenhaug K., Bilancio A., Farjot G., Priddle H., Sancho S., Peskett E., Pearce W., Meek S.E., Salpekar A., Waterfield M.D. et al. |
| Cluster analysis of an extensive human breast cancer cell line protein expression map database. Harris R.A., Yang A., Stein R.C., Lucy K., Brusten L., Herath A., Parekh R., Waterfield M.D., O'Hare M.J., Neville M.A. et al. Proteomics 2:212-223(2002) · UniProtKB (19) |
| Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors. Arcaro A., Zvelebil M.J., Wallasch C., Ullrich A., Waterfield M.D., Domin J. Mol. Cell. Biol. 20:3817-3830(2000) · UniProtKB (5) |
| The class II phosphoinositide 3-kinase PI3K-C2alpha is concentrated in the trans-Golgi network and present in clathrin-coated vesicles. Domin J., Gaidarov I., Smith M.E.K., Keen J.H., Waterfield M.D. J. Biol. Chem. 275:11943-11950(2000) · UniProtKB (1) |
| Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor. Weinkove D., Neufeld T.P., Twardzik T., Waterfield M.D., Leevers S.J. Curr. Biol. 9:1019-1029(1999) · Mapped (13) |
| Insulin activates the alpha isoform of class II phosphoinositide 3-kinase. Brown R.A., Domin J., Arcaro A., Waterfield M.D., Shepherd P.R. J. Biol. Chem. 274:14529-14532(1999) · UniProtKB (1) |
| Autophosphorylation of p110 delta phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo. Vanhaesebroeck B., Higashi K., Raven C., Welham M., Anderson S., Brennan P., Ward S.G., Waterfield M.D. EMBO J. 18:1292-1302(1999) · UniProtKB (1) |
| Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity. Arcaro A., Volinia S., Zvelebil M.J., Stein R.C., Watton S.J., Layton M.J., Gout I., Ahmadi K., Downward J., Waterfield M.D. J. Biol. Chem. 273:33082-33090(1998) · UniProtKB (1) |
| Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region. Gout I., Minami T., Hara K., Tsujishita Y., Filonenko V., Waterfield M.D., Yonezawa K. J. Biol. Chem. 273:30061-30064(1998) · UniProtKB (2) |
| Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase. Siegal G., Davis B., Kristensen S.M., Sankar A., Linacre J., Stein R.C., Panayotou G., Waterfield M.D., Driscoll P.C. J. Mol. Biol. 276:461-478(1998) · UniProtKB (1) |
| Cloning of a human phosphoinositide 3-kinase with a C2 domain which displays reduced sensitivity to the inhibitor wortmannin. Domin J., Pages F., Volinia S., Rittenhouse S.E., Zvelebil M.J., Stein R.C., Waterfield M.D. Biochem. J. 326:139-147(1997) · UniProtKB (1) |
| Phosphoinositide 3-kinases: a conserved family of signal transducers. Vanhaesebroeck B., Leevers S.J., Panayotou G., Waterfield M.D. Trends Biochem. Sci. 22:267-272(1997) · Mapped (11) |
| p60 is an adaptor for the Drosophila phosphoinositide 3-kinase, Dp110. Weinkove D., Leevers S.J., MacDougall L.K., Waterfield M.D. J. Biol. Chem. 272:14606-14610(1997) · UniProtKB (1) · Mapped (10) |
| P110delta, a novel phosphoinositide 3-kinase in leukocytes. Vanhaesebroeck B.A.M., Welham M.J., Kotani K., Stein R., Warne P.H., Zvelebil M.J., Higashi K., Volinia S., Downward J., Waterfield M.D. Proc. Natl. Acad. Sci. U.S.A. 94:4330-4335(1997) · UniProtKB (1) |
| Molecular cloning and biochemical characterization of a Drosophila phosphatidylinositol-specific phosphoinositide 3-kinase. Linassier C., MacDougall L.K., Domin J., Waterfield M.D. |
| Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.PtdIns 3-kinase complex. Panaretou C., Domin J., Cockcroft S., Waterfield M.D. J. Biol. Chem. 272:2477-2485(1997) · UniProtKB (1) · Mapped (3) |
| The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth. Leevers S.J., Weinkove D., MacDougall L.K., Hafen E., Waterfield M.D. |
| Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase. Renzoni D.A., Pugh D.J., Siligardi G., Das P., Morton C.J., Rossi C., Waterfield M.D., Campbell I.D., Ladbury J.E. Biochemistry 35:15646-15653(1996) · UniProtKB (2) |
| Receptor signalling: to sevenless, a daughter. MacDougall L.K., Waterfield M.D. Curr. Biol. 6:1250-1253(1996) · Mapped (284) |