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The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis.

Qian X., Li G., Vass W.C., Papageorge A., Walker R.C., Asnaghi L., Steinbach P.J., Tosato G., Hunter K., Lowy D.R.

Cancer Cell 16:246-258(2009) · Mapped (2)

Tumour-associated tenascin-C isoforms promote breast cancer cell invasion and growth by matrix metalloproteinase-dependent and independent mechanisms.

Hancox R.A., Allen M.D., Holliday D.L., Edwards D.R., Pennington C.J., Guttery D.S., Shaw J.A., Walker R.A., Pringle J.H., Jones J.L.

Breast Cancer Res. 11:R24-R24(2009) · Mapped (6)

Changes in NGF and NT-3 protein species in the superior cervical ganglion following axotomy of postganglionic axons.

Walker R.G., Foster A., Randolph C.L., Isaacson L.G.

Brain Res. 1255:1-8(2009) · Mapped (2)

A common variant in the 3'UTR of the GRIK4 glutamate receptor gene affects transcript abundance and protects against bipolar disorder.

Pickard B.S., Knight H.M., Hamilton R.S., Soares D.C., Walker R., Boyd J.K., Machell J., Maclean A., McGhee K.A., Condie A. et al.

Proc. Natl. Acad. Sci. U.S.A. 105:14940-14945(2008) · Mapped (3)

Huntington's disease-like 2 in Brazil--report of 4 patients.

Rodrigues G.G., Walker R.H., Brice A., Cazeneuve C., Russaouen O., Teive H.A., Munhoz R.P., Becker N., Raskin S., Werneck L.C. et al.

Mov. Disord. 23:2244-2247(2008) · Mapped (5)

The actions of Caenorhabditis elegans neuropeptide-like peptides (NLPs) on body wall muscle of Ascaris suum and pharyngeal muscle of C. elegans.

Papaioannou S., Holden-Dye L., Walker R.J.

Acta. Biol. Hung. 59 Suppl:189-197(2008) · Mapped (5)

Evidence for a role for cyclic AMP in modulating the action of 5-HT and an excitatory neuropeptide, FLP17A, in the pharyngeal muscle of Caenorhabditis elegans.

Papaioannou S., Holden-Dye L., Walker R.J.

Invert. Neurosci. 8:91-100(2008) · Mapped (5)

Bromodomain 4 activation predicts breast cancer survival.

Crawford N.P., Alsarraj J., Lukes L., Walker R.C., Officewala J.S., Yang H.H., Lee M.P., Ozato K., Hunter K.W.

Proc. Natl. Acad. Sci. U.S.A. 105:6380-6385(2008) · Mapped (10)

Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis.

Crawford N.P., Qian X., Ziogas A., Papageorge A.G., Boersma B.J., Walker R.C., Lukes L., Rowe W.L., Zhang J., Ambs S. et al.

PLoS Genet. 3:e214-e214(2007) · Mapped (2)

SLO, SLO, quick, quick, slow: calcium-activated potassium channels as regulators of Caenorhabditis elegans behaviour and targets for anthelmintics.

Holden-Dye L., O'Connor V., Hopper N.A., Walker R.J., Harder A., Bull K., Guest M.

Invert. Neurosci. 7:199-208(2007) · Mapped (1)

Intrinsic genetic characteristics determine tumor-modifying capacity of fibroblasts: matrix metalloproteinase-3 5A/5A genotype enhances breast cancer cell invasion.

Holliday D.L., Hughes S., Shaw J.A., Walker R.A., Jones J.L.

Breast Cancer Res. 9:R67-R67(2007) · Mapped (1)

The calcium-activated potassium channel, SLO-1, is required for the action of the novel cyclo-octadepsipeptide anthelmintic, emodepside, in Caenorhabditis elegans.

Guest M., Bull K., Walker R.J., Amliwala K., O'Connor V., Harder A., Holden-Dye L., Hopper N.A.

Int. J. Parasitol. 37:1577-1588(2007) · Mapped (6)

Genotype-phenotype associations in patients with severe hyperinsulinism of infancy.

Greer R.M., Shah J., Jeske Y.W., Brown D., Walker R.M., Cowley D., Bowling F.G., Liaskou D., Harris M., Thomsett M.J. et al.

Pediatr. Dev. Pathol. 10:25-34(2007) · Mapped (7)

Survivin is an independent predictor of short-term survival in poor prognostic breast cancer patients.

Hinnis A.R., Luckett J.C., Walker R.A.

Br. J. Cancer 96:639-645(2007) · Mapped (10)

A novel Cys1638Tyr NC1 domain substitution in alpha5(IV) collagen causes Alport syndrome with late onset renal failure without hearing loss or eye abnormalities.

Wilson J.C., Yoon H.S., Walker R.J., Eccles M.R.

Nephrol. Dial. Transplant. 22:1338-1346(2007) · Mapped (5)

Tbx1 regulation of myogenic differentiation in the limb and cranial mesoderm.

Dastjerdi A., Robson L., Walker R., Hadley J., Zhang Z., Rodriguez-Niedenfuhr M., Ataliotis P., Baldini A., Scambler P., Francis-West P.

Dev. Dyn. 236:353-363(2007) · Mapped (4)

Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo.

Yaccoby S., Ling W., Zhan F., Walker R., Barlogie B., Shaughnessy J.D. Jr.

Blood 109:2106-2111(2007) · Mapped (1)

Comparison of subtyping methods for differentiating Salmonella enterica serovar Typhimurium isolates obtained from food animal sources.

Foley S.L., White D.G., McDermott P.F., Walker R.D., Rhodes B., Fedorka-Cray P.J., Simjee S., Zhao S.

J. Clin. Microbiol. 44:3569-3577(2006) · UniProtKB (42)

Stimulated trans-acting factor of 50 kDa (Staf50) inhibits HIV-1 replication in human monocyte-derived macrophages.

Bouazzaoui A., Kreutz M., Eisert V., Dinauer N., Heinzelmann A., Hallenberger S., Strayle J., Walker R., Rubsamen-Waigmann H., Andreesen R. et al.

Virology 356:79-94(2006) · Mapped (6)

PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis.

Healy A.M., Izmailova E., Fitzgerald M., Walker R., Hattersley M., Silva M., Siebert E., Terkelsen J., Picarella D., Pickard M.D. et al.

J. Immunol. 177:1886-1893(2006) · Mapped (6)

Role of a FMRFamide-like family of neuropeptides in the pharyngeal nervous system of Caenorhabditis elegans.

Papaioannou S., Marsden D., Franks C.J., Walker R.J., Holden-Dye L.

J. Neurobiol. 65:304-319(2005) · UniProtKB (12) · Mapped (13)

Id4 is required for the correct timing of neural differentiation.

Bedford L., Walker R., Kondo T., van Cruchten I., King E.R., Sablitzky F.

Dev. Biol. 280:386-395(2005) · Mapped (19)

An unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis.

Furumoto H., Ying H., Chandramouli G.V., Zhao L., Walker R.L., Meltzer P.S., Willingham M.C., Cheng S.Y.

Mol. Cell. Biol. 25:124-135(2005) · Mapped (11)

Connexin 32 promoter P2 mutations: a mechanism of peripheral nerve dysfunction.

Houlden H., Girard M., Cockerell C., Ingram D., Wood N.W., Goossens M., Walker R.W., Reilly M.M.

Ann. Neurol. 56:730-734(2004) · Mapped (1)

Huntington's Disease-like 2 (HDL2) in North America and Japan.

Margolis R.L., Holmes S.E., Rosenblatt A., Gourley L., O'Hearn E., Ross C.A., Seltzer W.K., Walker R.H., Ashizawa T., Rasmussen A. et al.

Ann. Neurol. 56:670-674(2004) · Mapped (3)

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