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1 - 25 of 111 results for author:"Vogelstein B." in Literature citations

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Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS.

Agrawal N., Jiao Y., Sausen M., Leary R., Bettegowda C., Roberts N.J., Bhan S., Ho A.S., Khan Z., Bishop J. et al.

J. Clin. Endocrinol. Metab. 98:E364-9(2013) · Mapped (14)

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.

Sausen M., Leary R.J., Jones S., Wu J., Reynolds C.P., Liu X., Blackford A., Parmigiani G., Diaz L.A. Jr., Papadopoulos N. et al.

Nat. Genet. 45:12-17(2013) · Mapped (5)

GNAS codon 201 mutations are uncommon in intraductal papillary neoplasms of the bile duct.

Matthaei H., Wu J., Dal Molin M., Debeljak M., Lingohr P., Katabi N., Klimstra D.S., Adsay N.V., Eshleman J.R., Schulick R.D. et al.

HPB (Oxford) 14:677-683(2012) · Mapped (12)

Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma.

Agrawal N., Jiao Y., Bettegowda C., Hutfless S.M., Wang Y., David S., Cheng Y., Twaddell W.S., Latt N.L., Shin E.J. et al.

Cancer Discov 2:899-905(2012) · Mapped (3)

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas.

Jiao Y., Killela P.J., Reitman Z.J., Rasheed A.B., Heaphy C.M., de Wilde R.F., Rodriguez F.J., Rosemberg S., Oba-Shinjo S.M., Nagahashi Marie S.K. et al.

Oncotarget 3:709-722(2012) · Mapped (16)

Somatic mutations in CCK2R alter receptor activity that promote oncogenic phenotypes.

Willard M.D., Lajiness M.E., Wulur I.H., Feng B., Swearingen M.L., Uhlik M.T., Kinzler K.W., Velculescu V.E., Sjoblom T., Markowitz S.D. et al.

Mol. Cancer Res. 10:739-749(2012) · Mapped (6)

Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types.

Jones S., Li M., Parsons D.W., Zhang X., Wesseling J., Kristel P., Schmidt M.K., Markowitz S., Yan H., Bigner D. et al.

Hum. Mutat. 33:100-103(2012) · UniProtKB (1)

Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma.

Li M., Zhao H., Zhang X., Wood L.D., Anders R.A., Choti M.A., Pawlik T.M., Daniel H.D., Kannangai R., Offerhaus G.J. et al.

Nat. Genet. 43:828-829(2011) · Mapped (5)

Mutations in CIC and FUBP1 contribute to human oligodendroglioma.

Bettegowda C., Agrawal N., Jiao Y., Sausen M., Wood L.D., Hruban R.H., Rodriguez F.J., Cahill D.P., McLendon R., Riggins G. et al.

Science 333:1453-1455(2011) · Mapped (7)

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1.

Agrawal N., Frederick M.J., Pickering C.R., Bettegowda C., Chang K., Li R.J., Fakhry C., Xie T.X., Zhang J., Wang J. et al.

Science 333:1154-1157(2011) · Mapped (9)

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development.

Wu J., Matthaei H., Maitra A., Dal Molin M., Wood L.D., Eshleman J.R., Goggins M., Canto M.I., Schulick R.D., Edil B.H. et al.

Sci Transl Med 3:92ra66-92ra66(2011) · Mapped (12)

Altered telomeres in tumors with ATRX and DAXX mutations.

Heaphy C.M., de Wilde R.F., Jiao Y., Klein A.P., Edil B.H., Shi C., Bettegowda C., Rodriguez F.J., Eberhart C.G., Hebbar S. et al.

Science 333:425-425(2011) · Mapped (8)

Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome.

Reitman Z.J., Jin G., Karoly E.D., Spasojevic I., Yang J., Kinzler K.W., He Y., Bigner D.D., Vogelstein B., Yan H.

Proc. Natl. Acad. Sci. U.S.A. 108:3270-3275(2011) · Mapped (13)

DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors.

Jiao Y., Shi C., Edil B.H., de Wilde R.F., Klimstra D.S., Maitra A., Schulick R.D., Tang L.H., Wolfgang C.L., Choti M.A. et al.

Science 331:1199-1203(2011) · Mapped (22)

14-3-3sigma regulates B-cell homeostasis through stabilization of FOXO1.

Su Y.W., Hao Z., Hirao A., Yamamoto K., Lin W.J., Young A., Duncan G.S., Yoshida H., Wakeham A., Lang P.A. et al.

Proc. Natl. Acad. Sci. U.S.A. 108:1555-1560(2011) · Mapped (7)

PI3Kalpha inhibitors that inhibit metastasis.

Schmidt-Kittler O., Zhu J., Yang J., Liu G., Hendricks W., Lengauer C., Gabelli S.B., Kinzler K.W., Vogelstein B., Huso D.L. et al.

Oncotarget 1:339-348(2010) · Mapped (7)

Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma.

Jones S., Wang T.L., Shih I.e.M., Mao T.L., Nakayama K., Roden R., Glas R., Slamon D., Diaz L.A. Jr., Vogelstein B. et al.

Science 330:228-231(2010) · Mapped (9)

Structural effects of oncogenic PI3Kalpha mutations.

Gabelli S.B., Huang C.H., Mandelker D., Schmidt-Kittler O., Vogelstein B., Amzel L.M.

Curr. Top. Microbiol. Immunol. 347:43-53(2010) · Mapped (7)

Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation.

Ericson K., Gan C., Cheong I., Rago C., Samuels Y., Velculescu V.E., Kinzler K.W., Huso D.L., Vogelstein B., Papadopoulos N.

Proc. Natl. Acad. Sci. U.S.A. 107:2598-2603(2010) · Mapped (19)

Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations.

Lauring J., Cosgrove D.P., Fontana S., Gustin J.P., Konishi H., Abukhdeir A.M., Garay J.P., Mohseni M., Wang G.M., Higgins M.J. et al.

Oncogene 29:2337-2345(2010) · Mapped (12)

A frequent kinase domain mutation that changes the interaction between PI3Kalpha and the membrane.

Mandelker D., Gabelli S.B., Schmidt-Kittler O., Zhu J., Cheong I., Huang C.H., Kinzler K.W., Vogelstein B., Amzel L.M.

Proc. Natl. Acad. Sci. U.S.A. 106:16996-17001(2009) · UniProtKB (2) · Mapped (6)

Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells.

Yun J., Rago C., Cheong I., Pagliarini R., Angenendt P., Rajagopalan H., Schmidt K., Willson J.K., Markowitz S., Zhou S. et al.

Science 325:1555-1559(2009) · Mapped (8)

Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers.

Guda K., Moinova H., He J., Jamison O., Ravi L., Natale L., Lutterbaugh J., Lawrence E., Lewis S., Willson J.K. et al.

Proc. Natl. Acad. Sci. U.S.A. 106:12921-12925(2009) · UniProtKB (1) · Mapped (2)

SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer.

Blackford A., Serrano O.K., Wolfgang C.L., Parmigiani G., Jones S., Zhang X., Parsons D.W., Lin J.C., Leary R.J., Eshleman J.R. et al.

Clin. Cancer Res. 15:4674-4679(2009) · Mapped (2)

Genetic mutations associated with cigarette smoking in pancreatic cancer.

Blackford A., Parmigiani G., Kensler T.W., Wolfgang C., Jones S., Zhang X., Parsons D.W., Lin J.C., Leary R.J., Eshleman J.R. et al.

Cancer Res. 69:3681-3688(2009) · Mapped (413)

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