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1 - 25 of 55 results for author:"Verdin E." in Literature citations

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Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance.

Kasler H.G., Lim H.W., Mottet D., Collins A.M., Lee I.S., Verdin E.

EMBO J. 31:4453-4465(2012) · Mapped (8)

Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells.

Kwon H.S., Lim H.W., Wu J., Schnolzer M., Verdin E., Ott M.

J. Immunol. 188:2712-2721(2012) · UniProtKB (2) · Mapped (17)

Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes.

Schroder S., Cho S., Zeng L., Zhang Q., Kaehlcke K., Mak L., Lau J., Bisgrove D., Schnolzer M., Verdin E. et al.

J. Biol. Chem. 287:1090-1099(2012) · Mapped (7)

The first identification of lysine malonylation substrates and its regulatory enzyme.

Peng C., Lu Z., Xie Z., Cheng Z., Chen Y., Tan M., Luo H., Zhang Y., He W., Yang K. et al.

Mol. Cell. Proteomics 10:M111.012658.01-M111.012658.12(2011) · UniProtKB (22) · Mapped (2)

Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production.

Jing E., Emanuelli B., Hirschey M.D., Boucher J., Lee K.Y., Lombard D., Verdin E.M., Kahn C.R.

Proc. Natl. Acad. Sci. U.S.A. 108:14608-14613(2011) · Mapped (7)

SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome.

Hirschey M.D., Shimazu T., Jing E., Grueter C.A., Collins A.M., Aouizerat B., Stancakova A., Goetzman E., Lam M.M., Schwer B. et al.

Mol. Cell 44:177-190(2011) · Mapped (10)

SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2.

Hirschey M.D., Shimazu T., Capra J.A., Pollard K.S., Verdin E.

Aging (Albany NY) 3:635-642(2011) · UniProtKB (1) · Mapped (11)

SIRT3 and cancer: tumor promoter or suppressor?

Alhazzazi T.Y., Kamarajan P., Verdin E., Kapila Y.L.

Biochim. Biophys. Acta 1816:80-88(2011) · Mapped (1)

Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes.

Kasler H.G., Young B.D., Mottet D., Lim H.W., Collins A.M., Olson E.N., Verdin E.

J. Immunol. 186:4782-4793(2011) · Mapped (11)

Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation.

Qiu X., Brown K., Hirschey M.D., Verdin E., Chen D.

Cell Metab. 12:662-667(2010) · Mapped (11)

SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production.

Shimazu T., Hirschey M.D., Hua L., Dittenhafer-Reed K.E., Schwer B., Lombard D.B., Li Y., Bunkenborg J., Alt F.W., Denu J.M. et al.

Cell Metab. 12:654-661(2010) · Mapped (7)

Zmynd15 encodes a histone deacetylase-dependent transcriptional repressor essential for spermiogenesis and male fertility.

Yan W., Si Y., Slaymaker S., Li J., Zheng H., Young D.L., Aslanian A., Saunders L., Verdin E., Charo I.F.

J. Biol. Chem. 285:31418-31426(2010) · UniProtKB (6) · Mapped (5)

The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription.

Pagans S., Kauder S.E., Kaehlcke K., Sakane N., Schroeder S., Dormeyer W., Trievel R.C., Verdin E., Schnolzer M., Ott M.

Cell Host Microbe 7:234-244(2010) · Mapped (2)

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.

Hirschey M.D., Shimazu T., Goetzman E., Jing E., Schwer B., Lombard D.B., Grueter C.A., Harris C., Biddinger S., Ilkayeva O.R. et al.

Nature 464:121-125(2010) · Mapped (8)

Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM.

Malik S., Jiang S., Garee J.P., Verdin E., Lee A.V., O'Malley B.W., Zhang M., Belaguli N.S., Oesterreich S.

Mol. Cell. Biol. 30:399-412(2010) · UniProtKB (1) · Mapped (1)

A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein.

Cooper H.M., Huang J.Y., Verdin E., Spelbrink J.N.

PLoS ONE 4:e4986-e4986(2009) · UniProtKB (1) · Mapped (6)

HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism.

Mottet D., Pirotte S., Lamour V., Hagedorn M., Javerzat S., Bikfalvi A., Bellahcene A., Verdin E., Castronovo V.

Oncogene 28:243-256(2009) · Mapped (47)

Destabilization of ERBB2 transcripts by targeting 3' untranslated region messenger RNA associated HuR and histone deacetylase-6.

Scott G.K., Marx C., Berger C.E., Saunders L.R., Verdin E., Schafer S., Jung M., Benz C.C.

Mol. Cancer Res. 6:1250-1258(2008) · Mapped (10)

Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7.

Wang S., Li X., Parra M., Verdin E., Bassel-Duby R., Olson E.N.

Proc. Natl. Acad. Sci. U.S.A. 105:7738-7743(2008) · UniProtKB (2) · Mapped (7)

Conserved metabolic regulatory functions of sirtuins.

Schwer B., Verdin E.

Cell Metab. 7:104-112(2008) · Mapped (2)

Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs).

Schafer S., Saunders L., Eliseeva E., Velena A., Jung M., Schwienhorst A., Strasser A., Dickmanns A., Ficner R., Schlimme S. et al.

Bioorg. Med. Chem. 16:2011-2033(2008) · Mapped (1)

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.

Lombard D.B., Alt F.W., Cheng H.L., Bunkenborg J., Streeper R.S., Mostoslavsky R., Kim J., Yancopoulos G., Valenzuela D., Murphy A. et al.

Mol. Cell. Biol. 27:8807-8814(2007) · UniProtKB (1) · Mapped (10)

Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis.

North B.J., Verdin E.

PLoS ONE 2:e784-e784(2007) · Mapped (2)

Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase.

Ahuja N., Schwer B., Carobbio S., Waltregny D., North B.J., Castronovo V., Maechler P., Verdin E.

J. Biol. Chem. 282:33583-33592(2007) · UniProtKB (1) · Mapped (1)

Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription.

Bisgrove D.A., Mahmoudi T., Henklein P., Verdin E.

Proc. Natl. Acad. Sci. U.S.A. 104:13690-13695(2007) · Mapped (13)

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