1 - 25 of 38 results for author:"Venkitaraman A.R." in Literature citations
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| Expression of LY6D is induced at the surface of MCF10A cells by X-ray irradiation. Kurosawa M., Jeyasekharan A.D., Surmann E.M., Hashimoto N., Venkatraman V., Kurosawa G., Furukawa K., Venkitaraman A.R., Kurosawa Y. FEBS J. 279:4479-4491(2012) · Mapped (2) |
| Kruppel-associated Box (KRAB)-associated co-repressor (KAP-1) Ser-473 phosphorylation regulates heterochromatin protein 1beta (HP1-beta) mobilization and DNA repair in heterochromatin. Bolderson E., Savage K.I., Mahen R., Pisupati V., Graham M.E., Richard D.J., Robinson P.J., Venkitaraman A.R., Khanna K.K. J. Biol. Chem. 287:28122-28131(2012) · Mapped (5) |
| The breast cancer susceptibility gene BRCA2 is required for the maintenance of telomere homeostasis. Min J., Choi E.S., Hwang K., Kim J., Sampath S., Venkitaraman A.R., Lee H. J. Biol. Chem. 287:5091-5101(2012) · Mapped (22) |
| The GDI-like solubilizing factor PDEdelta sustains the spatial organization and signalling of Ras family proteins. Chandra A., Grecco H.E., Pisupati V., Perera D., Cassidy L., Skoulidis F., Ismail S.A., Hedberg C., Hanzal-Bayer M., Venkitaraman A.R. et al. Nat. Cell Biol. 14:148-158(2012) · Mapped (14) |
| Interrogation of the protein-protein interactions between human BRCA2 BRC repeats and RAD51 reveals atomistic determinants of affinity. Cole D.J., Rajendra E., Roberts-Thomson M., Hardwick B., McKenzie G.J., Payne M.C., Venkitaraman A.R., Skylaris C.K. PLoS Comput. Biol. 7:e1002096-e1002096(2011) · Mapped (23) |
| From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1. Sledz P., Stubbs C.J., Lang S., Yang Y.Q., McKenzie G.J., Venkitaraman A.R., Hyvonen M., Abell C. Angew. Chem. Int. Ed. Engl. 50:4003-4006(2011) · Mapped (1) |
| A mitotic function for the high-mobility group protein HMG20b regulated by its interaction with the BRC repeats of the BRCA2 tumor suppressor. Lee M., Daniels M.J., Garnett M.J., Venkitaraman A.R. Oncogene 30:3360-3369(2011) · Mapped (22) |
| Context dependence of checkpoint kinase 1 as a therapeutic target for pancreatic cancers deficient in the BRCA2 tumor suppressor. Hattori H., Skoulidis F., Russell P., Venkitaraman A.R. Mol. Cancer Ther. 10:670-678(2011) · Mapped (37) |
| Germline Brca2 heterozygosity promotes Kras(G12D) -driven carcinogenesis in a murine model of familial pancreatic cancer. Skoulidis F., Cassidy L.D., Pisupati V., Jonasson J.G., Bjarnason H., Eyfjord J.E., Karreth F.A., Lim M., Barber L.M., Clatworthy S.A. et al. Cancer Cell 18:499-509(2010) · Mapped (25) |
| Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates. Koike A., Nishikawa H., Wu W., Okada Y., Venkitaraman A.R., Ohta T. Cancer Res. 70:6746-6756(2010) · Mapped (5) |
| HERC2 is an E3 ligase that targets BRCA1 for degradation. Wu W., Sato K., Koike A., Nishikawa H., Koizumi H., Venkitaraman A.R., Ohta T. Cancer Res. 70:6384-6392(2010) · Mapped (3) |
| A mitotic role for the DNA damage-responsive CHK2 kinase. Sato K., Ohta T., Venkitaraman A.R. Nat. Cell Biol. 12:424-425(2010) · Mapped (9) |
| UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit. Garnett M.J., Mansfeld J., Godwin C., Matsusaka T., Wu J., Russell P., Pines J., Venkitaraman A.R. Nat. Cell Biol. 11:1363-1369(2009) · UniProtKB (2) · Mapped (2) |
| The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchange. Shivji M.K., Mukund S.R., Rajendra E., Chen S., Short J.M., Savill J., Klenerman D., Venkitaraman A.R. Proc. Natl. Acad. Sci. U.S.A. 106:13254-13259(2009) · Mapped (23) |
| The carboxyl terminus of Brca2 links the disassembly of Rad51 complexes to mitotic entry. Ayoub N., Rajendra E., Su X., Jeyasekharan A.D., Mahen R., Venkitaraman A.R. Curr. Biol. 19:1075-1085(2009) · Mapped (26) |
| The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51. Carreira A., Hilario J., Amitani I., Baskin R.J., Shivji M.K., Venkitaraman A.R., Kowalczykowski S.C. Cell 136:1032-1043(2009) · Mapped (23) |
| c-ABL tyrosine kinase stabilizes RAD51 chromatin association. Shimizu H., Popova M., Fleury F., Kobayashi M., Hayashi N., Sakane I., Kurumizaka H., Venkitaraman A.R., Takahashi M., Yamamoto K. Biochem. Biophys. Res. Commun. 382:286-291(2009) · Mapped (18) |
| The crystal structure of the N-terminal region of BUB1 provides insight into the mechanism of BUB1 recruitment to kinetochores. Bolanos-Garcia V.M., Kiyomitsu T., D'Arcy S., Chirgadze D.Y., Grossmann J.G., Matak-Vinkovic D., Venkitaraman A.R., Yanagida M., Robinson C.V., Blundell T.L. |
| Cell-cycle coordination between DNA replication and recombination revealed by a vertebrate N-end rule degron-Rad51. Su X., Bernal J.A., Venkitaraman A.R. Nat. Struct. Mol. Biol. 15:1049-1058(2008) · Mapped (5) |
| HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response. Ayoub N., Jeyasekharan A.D., Bernal J.A., Venkitaraman A.R. Nature 453:682-686(2008) · Mapped (6) |
| A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange. Shivji M.K., Davies O.R., Savill J.M., Bates D.L., Pellegrini L., Venkitaraman A.R. Nucleic Acids Res. 34:4000-4011(2006) · Mapped (18) |
| A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene. Fernando H., Reszka A.P., Huppert J., Ladame S., Rankin S., Venkitaraman A.R., Neidle S., Balasubramanian S. Biochemistry 45:7854-7860(2006) · Mapped (7) |
| A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair. Matsushita N., Kitao H., Ishiai M., Nagashima N., Hirano S., Okawa K., Ohta T., Yu D.S., McHugh P.J., Hickson I.D. et al. Mol. Cell 19:841-847(2005) · UniProtKB (1) |
| The RASSF1A isoform of RASSF1 promotes microtubule stability and suppresses tumorigenesis. van der Weyden L., Tachibana K.K., Gonzalez M.A., Adams D.J., Ng B.L., Petty R., Venkitaraman A.R., Arends M.J., Bradley A. Mol. Cell. Biol. 25:8356-8367(2005) · Mapped (5) |
| Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome. Sangrithi M.N., Bernal J.A., Madine M., Philpott A., Lee J., Dunphy W.G., Venkitaraman A.R. |