1 - 25 of 48 results for author:"Velculescu V.E." in Literature citations
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| Somatic mutations in CCK2R alter receptor activity that promote oncogenic phenotypes. Willard M.D., Lajiness M.E., Wulur I.H., Feng B., Swearingen M.L., Uhlik M.T., Kinzler K.W., Velculescu V.E., Sjoblom T., Markowitz S.D. et al. Mol. Cancer Res. 10:739-749(2012) · Mapped (6) |
| Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types. Jones S., Li M., Parsons D.W., Zhang X., Wesseling J., Kristel P., Schmidt M.K., Markowitz S., Yan H., Bigner D. et al. Hum. Mutat. 33:100-103(2012) · UniProtKB (1) |
| Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma. Li M., Zhao H., Zhang X., Wood L.D., Anders R.A., Choti M.A., Pawlik T.M., Daniel H.D., Kannangai R., Offerhaus G.J. et al. Nat. Genet. 43:828-829(2011) · Mapped (5) |
| Mutations in CIC and FUBP1 contribute to human oligodendroglioma. Bettegowda C., Agrawal N., Jiao Y., Sausen M., Wood L.D., Hruban R.H., Rodriguez F.J., Cahill D.P., McLendon R., Riggins G. et al. Science 333:1453-1455(2011) · Mapped (7) |
| Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Agrawal N., Frederick M.J., Pickering C.R., Bettegowda C., Chang K., Li R.J., Fakhry C., Xie T.X., Zhang J., Wang J. et al. Science 333:1154-1157(2011) · Mapped (9) |
| Somatic mutations of PPP2R1A in ovarian and uterine carcinomas. Shih I.e.M., Panuganti P.K., Kuo K.T., Mao T.L., Kuhn E., Jones S., Velculescu V.E., Kurman R.J., Wang T.L. Am. J. Pathol. 178:1442-1447(2011) · Mapped (9) |
| Expression of p16 and retinoblastoma determines response to CDK4/6 inhibition in ovarian cancer. Konecny G.E., Winterhoff B., Kolarova T., Qi J., Manivong K., Dering J., Yang G., Chalukya M., Wang H.J., Anderson L. et al. Clin. Cancer Res. 17:1591-1602(2011) · Mapped (20) |
| DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. Jiao Y., Shi C., Edil B.H., de Wilde R.F., Klimstra D.S., Maitra A., Schulick R.D., Tang L.H., Wolfgang C.L., Choti M.A. et al. Science 331:1199-1203(2011) · Mapped (22) |
| Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Jones S., Wang T.L., Shih I.e.M., Mao T.L., Nakayama K., Roden R., Glas R., Slamon D., Diaz L.A. Jr., Vogelstein B. et al. Science 330:228-231(2010) · Mapped (9) |
| Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation. Ericson K., Gan C., Cheong I., Rago C., Samuels Y., Velculescu V.E., Kinzler K.W., Huso D.L., Vogelstein B., Papadopoulos N. Proc. Natl. Acad. Sci. U.S.A. 107:2598-2603(2010) · Mapped (18) |
| Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. Yun J., Rago C., Cheong I., Pagliarini R., Angenendt P., Rajagopalan H., Schmidt K., Willson J.K., Markowitz S., Zhou S. et al. Science 325:1555-1559(2009) · Mapped (7) |
| Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers. Guda K., Moinova H., He J., Jamison O., Ravi L., Natale L., Lutterbaugh J., Lawrence E., Lewis S., Willson J.K. et al. Proc. Natl. Acad. Sci. U.S.A. 106:12921-12925(2009) · UniProtKB (1) · Mapped (2) |
| SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer. Blackford A., Serrano O.K., Wolfgang C.L., Parmigiani G., Jones S., Zhang X., Parsons D.W., Lin J.C., Leary R.J., Eshleman J.R. et al. Clin. Cancer Res. 15:4674-4679(2009) · Mapped (2) |
| Genetic mutations associated with cigarette smoking in pancreatic cancer. Blackford A., Parmigiani G., Kensler T.W., Wolfgang C., Jones S., Zhang X., Parsons D.W., Lin J.C., Leary R.J., Eshleman J.R. et al. Cancer Res. 69:3681-3688(2009) · Mapped (420) |
| Frequent activating mutations of PIK3CA in ovarian clear cell carcinoma. Kuo K.T., Mao T.L., Jones S., Veras E., Ayhan A., Wang T.L., Glas R., Slamon D., Velculescu V.E., Kuman R.J. et al. Am. J. Pathol. 174:1597-1601(2009) · Mapped (7) |
| Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. Jones S., Hruban R.H., Kamiyama M., Borges M., Zhang X., Parsons D.W., Lin J.C., Palmisano E., Brune K., Jaffee E.M. et al. |
| IDH1 and IDH2 mutations in gliomas. Yan H., Parsons D.W., Jin G., McLendon R., Rasheed B.A., Yuan W., Kos I., Batinic-Haberle I., Jones S., Riggins G.J. et al. N. Engl. J. Med. 360:765-773(2009) · Mapped (13) |
| Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Jones S., Zhang X., Parsons D.W., Lin J.C., Leary R.J., Angenendt P., Mankoo P., Carter H., Kamiyama H., Jimeno A. et al. |
| An integrated genomic analysis of human glioblastoma multiforme. Parsons D.W., Jones S., Zhang X., Lin J.C.-H., Leary R.J., Angenendt P., Mankoo P., Carter H., Siu I.-M., Gallia G.L. et al. |
| Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers. Barber T.D., McManus K., Yuen K.W., Reis M., Parmigiani G., Shen D., Barrett I., Nouhi Y., Spencer F., Markowitz S. et al. Proc. Natl. Acad. Sci. U.S.A. 105:3443-3448(2008) · Mapped (29) |
| The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations. Huang C.-H., Mandelker D., Schmidt-Kittler O., Samuels Y., Velculescu V.E., Kinzler K.W., Vogelstein B., Gabelli S.B., Amzel L.M. |
| Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T. Zhang X., Guo A., Yu J., Possemato A., Chen Y., Zheng W., Polakiewicz R.D., Kinzler K.W., Vogelstein B., Velculescu V.E. et al. Proc. Natl. Acad. Sci. U.S.A. 104:4060-4064(2007) · Mapped (13) |
| The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT. Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X., Diaz L.A. Jr., Velculescu V.E., Parmigiani G. et al. Nat. Biotechnol. 24:1573-1580(2006) · UniProtKB (2,305) |
| Recurrent KRAS codon 146 mutations in human colorectal cancer. Edkins S., O'Meara S., Parker A., Stevens C., Reis M., Jones S., Greenman C., Davies H., Dalgliesh G., Forbes S. et al. Cancer Biol. Ther. 5:928-932(2006) · Mapped (7) |
| The consensus coding sequences of human breast and colorectal cancers. Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N. et al. |