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1 - 25 of 36 results for author:"Velculescu V.E."Drop in Literature Citations

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Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells.

Yun J., Rago C., Cheong I., Pagliarini R., Angenendt P., Rajagopalan H., Schmidt K., Willson J.K., Markowitz S., Zhou S. et al.

Science 325:1555-1559(2009) · Mapped (8)

Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers.

Guda K., Moinova H., He J., Jamison O., Ravi L., Natale L., Lutterbaugh J., Lawrence E., Lewis S., Willson J.K. et al.

Proc. Natl. Acad. Sci. U.S.A. 106:12921-12925(2009) · Mapped (3)

SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer.

Blackford A., Serrano O.K., Wolfgang C.L., Parmigiani G., Jones S., Zhang X., Parsons D.W., Lin J.C., Leary R.J., Eshleman J.R. et al.

Clin. Cancer Res. 15:4674-4679(2009) · Mapped (3)

Genetic mutations associated with cigarette smoking in pancreatic cancer.

Blackford A., Parmigiani G., Kensler T.W., Wolfgang C., Jones S., Zhang X., Parsons D.W., Lin J.C., Leary R.J., Eshleman J.R. et al.

Cancer Res. 69:3681-3688(2009) · Mapped (508)

Frequent activating mutations of PIK3CA in ovarian clear cell carcinoma.

Kuo K.T., Mao T.L., Jones S., Veras E., Ayhan A., Wang T.L., Glas R., Slamon D., Velculescu V.E., Kuman R.J. et al.

Am. J. Pathol. 174:1597-1601(2009) · Mapped (6)

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene.

Jones S., Hruban R.H., Kamiyama M., Borges M., Zhang X., Parsons D.W., Lin J.C., Palmisano E., Brune K., Jaffee E.M. et al.

Science 324:217-217(2009) · Mapped (2)

IDH1 and IDH2 mutations in gliomas.

Yan H., Parsons D.W., Jin G., McLendon R., Rasheed B.A., Yuan W., Kos I., Batinic-Haberle I., Jones S., Riggins G.J. et al.

N. Engl. J. Med. 360:765-773(2009) · Mapped (15)

An integrated genomic analysis of human glioblastoma multiforme.

Parsons D.W., Jones S., Zhang X., Lin J.C.-H., Leary R.J., Angenendt P., Mankoo P., Carter H., Siu I.-M., Gallia G.L. et al.

Science 321:1807-1812(2008) · UniProtKB (1) · Mapped (9)

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers.

Barber T.D., McManus K., Yuen K.W., Reis M., Parmigiani G., Shen D., Barrett I., Nouhi Y., Spencer F., Markowitz S. et al.

Proc. Natl. Acad. Sci. U.S.A. 105:3443-3448(2008) · Mapped (29)

The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations.

Huang C.H., Mandelker D., Schmidt-Kittler O., Samuels Y., Velculescu V.E., Kinzler K.W., Vogelstein B., Gabelli S.B., Amzel L.M.

Science 318:1744-1748(2007) · Mapped (11)

Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T.

Zhang X., Guo A., Yu J., Possemato A., Chen Y., Zheng W., Polakiewicz R.D., Kinzler K.W., Vogelstein B., Velculescu V.E. et al.

Proc. Natl. Acad. Sci. U.S.A. 104:4060-4064(2007) · Mapped (14)

The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT.

Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X., Diaz L.A. Jr., Velculescu V.E., Parmigiani G. et al.

Nat. Biotechnol. 24:1573-1580(2006) · UniProtKB (2,305)

Recurrent KRAS codon 146 mutations in human colorectal cancer.

Edkins S., O'Meara S., Parker A., Stevens C., Reis M., Jones S., Greenman C., Davies H., Dalgliesh G., Forbes S. et al.

Cancer Biol. Ther. 5:928-932(2006) · Mapped (8)

The consensus coding sequences of human breast and colorectal cancers.

Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N. et al.

Science 314:268-274(2006) · UniProtKB (980) · Mapped (4)

Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers.

Wood L.D., Calhoun E.S., Silliman N., Ptak J., Szabo S., Powell S.M., Riggins G.J., Wang T.L., Yan H., Gazdar A. et al.

Hum. Mutat. 27:1060-1061(2006) · Mapped (10)

Homozygous deletion of MKK4 in ovarian serous carcinoma.

Nakayama K., Nakayama N., Davidson B., Katabuchi H., Kurman R.J., Velculescu V.E., Shih I.e.M., Wang T.L.

Cancer Biol. Ther. 5:630-634(2006) · Mapped (9)

Mutant PIK3CA promotes cell growth and invasion of human cancer cells.

Samuels Y., Diaz L.A. Jr., Schmidt-Kittler O., Cummins J.M., Delong L., Cheong I., Rago C., Huso D.L., Lengauer C., Kinzler K.W. et al.

Cancer Cell 7:561-573(2005) · Mapped (6)

Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid.

Di C., Liao S., Adamson D.C., Parrett T.J., Broderick D.K., Shi Q., Lengauer C., Cummins J.M., Velculescu V.E., Fults D.W. et al.

Cancer Res. 65:919-924(2005) · Mapped (2)

Oncogenic mutations of PIK3CA in human cancers.

Samuels Y., Velculescu V.E.

Cell Cycle 3:1221-1224(2004) · Mapped (6)

Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas.

Broderick D.K., Di C., Parrett T.J., Samuels Y.R., Cummins J.M., McLendon R.E., Fults D.W., Velculescu V.E., Bigner D.D., Yan H.

Cancer Res. 64:5048-5050(2004) · UniProtKB (1) · Mapped (5)

The PIK3CA gene is mutated with high frequency in human breast cancers.

Bachman K.E., Argani P., Samuels Y., Silliman N., Ptak J., Szabo S., Konishi H., Karakas B., Blair B.G., Lin C. et al.

Cancer Biol. Ther. 3:772-775(2004) · Mapped (6)

Mutational analysis of the tyrosine phosphatome in colorectal cancers.

Wang Z., Shen D., Parsons D.W., Bardelli A., Sager J., Szabo S., Ptak J., Silliman N., Peters B.A., van der Heijden M.S. et al.

Science 304:1164-1166(2004) · UniProtKB (1)

Three classes of genes mutated in colorectal cancers with chromosomal instability.

Wang Z., Cummins J.M., Shen D., Cahill D.P., Jallepalli P.V., Wang T.-L., Parsons D.W., Traverso G., Awad M., Silliman N. et al.

Cancer Res. 64:2998-3001(2004) · UniProtKB (1) · Mapped (1)

High frequency of mutations of the PIK3CA gene in human cancers.

Samuels Y., Wang Z., Bardelli A., Silliman N., Ptak J., Szabo S., Yan H., Gazdar A., Powell S.M., Riggins G.J. et al.

Science 304:554-554(2004) · UniProtKB (1) · Mapped (5)

Inactivation of hCDC4 can cause chromosomal instability.

Rajagopalan H., Jallepalli P.V., Rago C., Velculescu V.E., Kinzler K.W., Vogelstein B., Lengauer C.

Nature 428:77-81(2004) · Mapped (5)

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