1 - 25 of 37 results for author:"Varadi A." in Literature citations
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| Stimulus-induced expression of the ABCG2 multidrug transporter in HepG2 hepatocarcinoma model cells involves the ERK1/2 cascade and alternative promoters. de Boussac H., Orban T.I., Varady G., Tihanyi B., Bacquet C., Brozik A., Varadi A., Sarkadi B., Aranyi T. Biochem. Biophys. Res. Commun. 426:172-176(2012) · Mapped (5) |
| ABCC6 expression is regulated by CCAAT/enhancer-binding protein activating a primate-specific sequence located in the first intron of the gene. Ratajewski M., de Boussac H., Sachrajda I., Bacquet C., Kovacs T., Varadi A., Pulaski L., Aranyi T. J. Invest. Dermatol. 132:2709-2717(2012) · Mapped (9) |
| ABCC6 does not transport vitamin K3-glutathione conjugate from the liver: relevance to pathomechanisms of pseudoxanthoma elasticum. Fulop K., Jiang Q., Wetering K.V., Pomozi V., Szabo P.T., Aranyi T., Sarkadi B., Borst P., Uitto J., Varadi A. Biochem. Biophys. Res. Commun. 415:468-471(2011) · Mapped (7) |
| Translationally controlled tumour protein (TCTP) is a novel glucose-regulated protein that is important for survival of pancreatic beta cells. Diraison F., Hayward K., Sanders K.L., Brozzi F., Lajus S., Hancock J., Francis J.E., Ainscow E., Bommer U.A., Molnar E. et al. Diabetologia 54:368-379(2011) · Mapped (2) |
| The abcc6a gene expression is required for normal zebrafish development. Li Q., Sadowski S., Frank M., Chai C., Varadi A., Ho S.Y., Lou H., Dean M., Thisse C., Thisse B. et al. J. Invest. Dermatol. 130:2561-2568(2010) · Mapped (1) |
| The ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes. de Boussac H., Ratajewski M., Sachrajda I., Koblos G., Tordai A., Pulaski L., Buday L., Varadi A., Aranyi T. J. Biol. Chem. 285:22800-22808(2010) · Mapped (25) |
| The R1141X loss-of-function mutation of the ABCC6 gene is a strong genetic risk factor for coronary artery disease. Koblos G., Andrikovics H., Prohaszka Z., Tordai A., Varadi A., Aranyi T. Genet Test Mol Biomarkers 14:75-78(2010) · Mapped (6) |
| Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties. Hegedus C., Ozvegy-Laczka C., Apati A., Magocsi M., Nemet K., Orfi L., Keri G., Katona M., Takats Z., Varadi A. et al. Br. J. Pharmacol. 158:1153-1164(2009) · Mapped (5) |
| Clustering of disease-causing mutations on the domain-domain interfaces of ABCC6. Fulop K., Barna L., Symmons O., Zavodszky P., Varadi A. Biochem. Biophys. Res. Commun. 379:706-709(2009) · Mapped (6) |
| The high turnover Drosophila multidrug resistance-associated protein shares the biochemical features of its human orthologues. Szeri F., Ilias A., Pomozi V., Robinow S., Bakos E., Varadi A. Biochim. Biophys. Acta 1788:402-409(2009) · Mapped (17) |
| How segmental duplications shape our genome: recent evolution of ABCC6 and PKD1 Mendelian disease genes. Symmons O., Varadi A., Aranyi T. Mol. Biol. Evol. 25:2601-2613(2008) · Mapped (11) |
| Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter. Ozvegy-Laczka C., Laczko R., Hegedus C., Litman T., Varady G., Goda K., Hegedus T., Dokholyan N.V., Sorrentino B.P., Varadi A. et al. J. Biol. Chem. 283:26059-26070(2008) · Mapped (5) |
| Membrane cholesterol selectively modulates the activity of the human ABCG2 multidrug transporter. Telbisz A., Muller M., Ozvegy-Laczka C., Homolya L., Szente L., Varadi A., Sarkadi B. Biochim. Biophys. Acta 1768:2698-2713(2007) · Mapped (5) |
| Developing oligodendrocytes express functional GABA(B) receptors that stimulate cell proliferation and migration. Luyt K., Slade T.P., Dorward J.J., Durant C.F., Wu Y., Shigemoto R., Mundell S.J., Varadi A., Molnar E. J. Neurochem. 100:822-840(2007) · Mapped (3) |
| Co-expression of human ABCG5 and ABCG8 in insect cells generates an androstan stimulated membrane ATPase activity. Muller M., Klein I., Kopacsi S., Remaley A.T., Rajnavolgyi E., Sarkadi B., Varadi A. FEBS Lett. 580:6139-6144(2006) · Mapped (10) |
| Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells: against a role in organelle cation homeostasis. Varadi A., Grant A., McCormack M., Nicolson T., Magistri M., Mitchell K.J., Halestrap A.P., Yuan H., Schwappach B., Rutter G.A. Diabetologia 49:1567-1577(2006) · Mapped (8) |
| Myosin Va transports dense core secretory vesicles in pancreatic MIN6 beta-cells. Varadi A., Tsuboi T., Rutter G.A. Mol. Biol. Cell 16:2670-2680(2005) · Mapped (29) |
| Identification of a DNA methylation-dependent activator sequence in the pseudoxanthoma elasticum gene, ABCC6. Aranyi T., Ratajewski M., Bardoczy V., Pulaski L., Bors A., Tordai A., Varadi A. J. Biol. Chem. 280:18643-18650(2005) · Mapped (6) |
| Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition. Oezvegy-Laczka C., Koebloes G., Sarkadi B., Varadi A. Biochim. Biophys. Acta 1668:53-63(2005) · UniProtKB (1) · Mapped (4) |
| Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface. Ozvegy-Laczka C., Varady G., Koblos G., Ujhelly O., Cervenak J., Schuetz J.D., Sorrentino B.P., Koomen G.J., Varadi A., Nemet K. et al. J. Biol. Chem. 280:4219-4227(2005) · Mapped (5) |
| The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance-associated protein family. Tarnay J.N., Szeri F., Ilias A., Annilo T., Sung C., Le Saux O., Varadi A., Dean M., Boyd C.D., Robinow S. Insect Mol. Biol. 13:539-548(2004) · Mapped (32) |
| Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1. Varadi A., Johnson-Cadwell L.I., Cirulli V., Yoon Y., Allan V.J., Rutter G.A. J. Cell. Sci. 117:4389-4400(2004) · Mapped (9) |
| Metabotropic glutamate receptors are expressed in adult human glial progenitor cells. Luyt K., Varadi A., Halfpenny C.A., Scolding N.J., Molnar E. Biochem. Biophys. Res. Commun. 319:120-129(2004) · Mapped (13) |
| Subcellular localization and N-glycosylation of human ABCC6, expressed in MDCKII cells. Sinko E., Ilias A., Ujhelly O., Homolya L., Scheffer G.L., Bergen A.A., Sarkadi B., Varadi A. Biochem. Biophys. Res. Commun. 308:263-269(2003) · UniProtKB (1) · Mapped (5) |
| Analysis of large structural changes of the factor VIII gene, involving intron 1 and 22, in severe hemophilia A. Andrikovics H., Klein I., Bors A., Nemes L., Marosi A., Varadi A., Tordai A. Haematologica 88:778-784(2003) · Mapped (12) |