| Tuberin inhibits production of the matrix protein fibronectin in diabetes. Habib S.L., Yadav M., Tizani S., Bhandari B., Valente A.J.
J. Am. Soc. Nephrol. 23:1652-1662(2012) · Mapped (6) |
| Angiotensin-II type 1 receptor and NOX2 mediate TCF/LEF and CREB dependent WISP1 induction and cardiomyocyte hypertrophy. Shanmugam P., Valente A.J., Prabhu S.D., Venkatesan B., Yoshida T., Delafontaine P., Chandrasekar B.
J. Mol. Cell. Cardiol. 50:928-938(2011) · Mapped (5) |
| Interleukin-18/WNT1-inducible signaling pathway protein-1 signaling mediates human saphenous vein smooth muscle cell proliferation. Reddy V.S., Valente A.J., Delafontaine P., Chandrasekar B.
J. Cell. Physiol. 226:3303-3315(2011) · Mapped (7) |
| Novel regulation of parkin function through c-Abl-mediated tyrosine phosphorylation: implications for Parkinson's disease. Imam S.Z., Zhou Q., Yamamoto A., Valente A.J., Ali S.F., Bains M., Roberts J.L., Kahle P.J., Clark R.A., Li S.
J. Neurosci. 31:157-163(2011) · Mapped (9) |
| Interleukin-18 induces EMMPRIN expression in primary cardiomyocytes via JNK/Sp1 signaling and MMP-9 in part via EMMPRIN and through AP-1 and NF-kappaB activation. Reddy V.S., Prabhu S.D., Mummidi S., Valente A.J., Venkatesan B., Shanmugam P., Delafontaine P., Chandrasekar B.
Am. J. Physiol. Heart Circ. Physiol. 299:H1242-54(2010) · Mapped (9) |
| EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via Rac1-dependent PI3K/Akt/IKK/NF-kappaB andMKK7/JNK/AP-1 signaling. Venkatesan B., Valente A.J., Prabhu S.D., Shanmugam P., Delafontaine P., Chandrasekar B.
J. Mol. Cell. Cardiol. 49:655-663(2010) · Mapped (10) |
| WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death. Venkatesan B., Prabhu S.D., Venkatachalam K., Mummidi S., Valente A.J., Clark R.A., Delafontaine P., Chandrasekar B.
Cell. Signal. 22:809-820(2010) · Mapped (4) |
| Regulation of phagocyte NADPH oxidase by hydrogen peroxide through a Ca(2+)/c-Abl signaling pathway. El Jamali A., Valente A.J., Clark R.A.
Free Radic. Biol. Med. 48:798-810(2010) · Mapped (4) |
| WISP1, a pro-mitogenic, pro-survival factor, mediates tumor necrosis factor-alpha (TNF-alpha)-stimulated cardiac fibroblast proliferation but inhibits TNF-alpha-induced cardiomyocyte death. Venkatachalam K., Venkatesan B., Valente A.J., Melby P.C., Nandish S., Reusch J.E., Clark R.A., Chandrasekar B.
J. Biol. Chem. 284:14414-14427(2009) · Mapped (10) |
| Neutralization of interleukin-18 ameliorates ischemia/reperfusion-induced myocardial injury. Venkatachalam K., Prabhu S.D., Reddy V.S., Boylston W.H., Valente A.J., Chandrasekar B.
J. Biol. Chem. 284:7853-7865(2009) · Mapped (3) |
| Adiponectin blocks interleukin-18-mediated endothelial cell death via APPL1-dependent AMP-activated protein kinase (AMPK) activation and IKK/NF-kappaB/PTEN suppression. Chandrasekar B., Boylston W.H., Venkatachalam K., Webster N.J., Prabhu S.D., Valente A.J.
J. Biol. Chem. 283:24889-24898(2008) · Mapped (8) |
| Interleukin-18 suppresses adiponectin expression in 3T3-L1 adipocytes via a novel signal transduction pathway involving ERK1/2-dependent NFATc4 phosphorylation. Chandrasekar B., Patel D.N., Mummidi S., Kim J.W., Clark R.A., Valente A.J.
J. Biol. Chem. 283:4200-4209(2008) · Mapped (10) |
| Interleukin-18 stimulates fibronectin expression in primary human cardiac fibroblasts via PI3K-Akt-dependent NF-kappaB activation. Reddy V.S., Harskamp R.E., van Ginkel M.W., Calhoon J., Baisden C.E., Kim I.S., Valente A.J., Chandrasekar B.
J. Cell. Physiol. 215:697-707(2008) · Mapped (16) |
| IL-17 stimulates MMP-1 expression in primary human cardiac fibroblasts via p38 MAPK- and ERK1/2-dependent C/EBP-beta , NF-kappaB, and AP-1 activation. Cortez D.M., Feldman M.D., Mummidi S., Valente A.J., Steffensen B., Vincenti M., Barnes J.L., Chandrasekar B.
Am. J. Physiol. Heart Circ. Physiol. 293:H3356-65(2007) · Mapped (29) |
| Interleukin-17 stimulates C-reactive protein expression in hepatocytes and smooth muscle cells via p38 MAPK and ERK1/2-dependent NF-kappaB and C/EBPbeta activation. Patel D.N., King C.A., Bailey S.R., Holt J.W., Venkatachalam K., Agrawal A., Valente A.J., Chandrasekar B.
J. Biol. Chem. 282:27229-27238(2007) · Mapped (22) |
| A preliminary study of the baboon prostate pathophysiology. Mubiru J.N., Hubbard G.B., Dick E.J. Jr., Butler S.D., Valente A.J., Troyer D.A., Rogers J.
Prostate 67:1421-1431(2007) · UniProtKB (1) |
| NOX1 NADPH oxidase regulation by the NOXA1 SH3 domain. Valente A.J., Jamali A.E., Epperson T.K., Gamez M.J., Pearson D.W., Clark R.A.
Free Radic. Biol. Med. 43:384-396(2007) · UniProtKB (1) · Mapped (1) |
| TLR4-NOX4-AP-1 signaling mediates lipopolysaccharide-induced CXCR6 expression in human aortic smooth muscle cells. Patel D.N., Bailey S.R., Gresham J.K., Schuchman D.B., Shelhamer J.H., Goldstein B.J., Foxwell B.M., Stemerman M.B., Maranchie J.K., Valente A.J. et al.
Biochem. Biophys. Res. Commun. 347:1113-1120(2006) · Mapped (2) |
| Interleukin-18 induces human cardiac endothelial cell death via a novel signaling pathway involving NF-kappaB-dependent PTEN activation. Chandrasekar B., Valente A.J., Freeman G.L., Mahimainathan L., Mummidi S.
Biochem. Biophys. Res. Commun. 339:956-963(2006) · Mapped (7) |
| The pro-atherogenic cytokine interleukin-18 induces CXCL16 expression in rat aortic smooth muscle cells via MyD88, interleukin-1 receptor-associated kinase, tumor necrosis factor receptor-associated factor 6, c-Src, phosphatidylinositol 3-kinase, Akt, c-Jun N-terminal kinase, and activator protein-1 signaling. Chandrasekar B., Mummidi S., Valente A.J., Patel D.N., Bailey S.R., Freeman G.L., Hatano M., Tokuhisa T., Jensen L.E.
J. Biol. Chem. 280:26263-26277(2005) · UniProtKB (1) · Mapped (13) |
| A variant of the alpha-methyl-acyl-CoA racemase gene created by a deletion in exon 5 and its expression in prostate cancer. Mubiru J.N., Valente A.J., Troyer D.A.
Prostate 65:117-123(2005) · UniProtKB (1) |
| Alternative spliced variants of the alpha-methylacyl-CoA racemase gene and their expression in prostate cancer. Mubiru J.N., Shen-Ong G.L., Valente A.J., Troyer D.A.
Gene 327:89-98(2004) · UniProtKB (2) |
| IkappaBalpha-dependent regulation of low-shear flow-induced NF-kappa B activity: role of nitric oxide. Mohan S., Hamuro M., Sorescu G.P., Koyoma K., Sprague E.A., Jo H., Valente A.J., Prihoda T.J., Natarajan M.
Am. J. Physiol., Cell Physiol. 284:C1039-47(2003) · Mapped (3) |
| Regulation of calreticulin expression during induction of differentiation in human myeloid cells. Evidence for remodeling of the endoplasmic reticulum. Clark R.A., Li S.L., Pearson D.W., Leidal K.G., Clark J.R., Denning G.M., Reddick R., Krause K.H., Valente A.J.
J. Biol. Chem. 277:32369-32378(2002) · Mapped (4) |
| Multiple PU.1 sites cooperate in the regulation of p40(phox) transcription during granulocytic differentiation of myeloid cells. Li S.L., Valente A.J., Qiang M., Schlegel W., Gamez M., Clark R.A.
Blood 99:4578-4587(2002) · Mapped (7) |
