7 results for author:"Turci S.M." in Literature citations
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| Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors. Buchanan J.L., Newcomb J.R., Carney D.P., Chaffee S.C., Chai L., Cupples R., Epstein L.F., Gallant P., Gu Y., Harmange J.C. et al. Bioorg. Med. Chem. Lett. 21:2394-2399(2011) · UniProtKB (1) |
| Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation. DiMauro E.F., Newcomb J., Nunes J.J., Bemis J.E., Boucher C., Chai L., Chaffee S.C., Deak H.L., Epstein L.F., Faust T. et al. J. Med. Chem. 51:1681-1694(2008) · Mapped (1) |
| Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity. Martin M.W., Newcomb J., Nunes J.J., Boucher C., Chai L., Epstein L.F., Faust T., Flores S., Gallant P., Gore A. et al. J. Med. Chem. 51:1637-1648(2008) · Mapped (1) |
| N-(3-(phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: structure, synthesis and SAR. Deak H.L., Newcomb J.R., Nunes J.J., Boucher C., Cheng A.C., DiMauro E.F., Epstein L.F., Gallant P., Hodous B.L., Huang X. et al. Bioorg. Med. Chem. Lett. 18:1172-1176(2008) · Mapped (1) |
| Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic properties. Martin M.W., Newcomb J., Nunes J.J., Bemis J.E., McGowan D.C., White R.D., Buchanan J.L., DiMauro E.F., Boucher C., Faust T. et al. Bioorg. Med. Chem. Lett. 17:2299-2304(2007) · Mapped (1) |
| Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity. DiMauro E.F., Newcomb J., Nunes J.J., Bemis J.E., Boucher C., Buchanan J.L., Buckner W.H., Cee V.J., Chai L., Deak H.L. et al. J. Med. Chem. 49:5671-5686(2006) · Mapped (1) |
| Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activity. Martin M.W., Newcomb J., Nunes J.J., McGowan D.C., Armistead D.M., Boucher C., Buchanan J.L., Buckner W., Chai L., Elbaum D. et al. J. Med. Chem. 49:4981-4991(2006) · Mapped (1) |