| Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis. Shi Y., Ghosh M.C., Tong W.H., Rouault T.A.
Hum. Mol. Genet. 18:3014-3025(2009) · Mapped (4) |
| BLT2 is expressed in PanINs, IPMNs, pancreatic cancer and stimulates tumour cell proliferation. Hennig R., Osman T., Esposito I., Giese N., Rao S.M., Ding X.Z., Tong W.G., Buchler M.W., Yokomizo T., Friess H. et al.
Br. J. Cancer 99:1064-1073(2008) · Mapped (4) |
| Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis. Yamaoka T., Yan F., Cao H., Hobbs S.S., Dise R.S., Tong W., Polk D.B.
Proc. Natl. Acad. Sci. U.S.A. 105:11772-11777(2008) · Mapped (16) |
| Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice. Ghosh M.C., Tong W.H., Zhang D., Ollivierre-Wilson H., Singh A., Krishna M.C., Mitchell J.B., Rouault T.A.
Proc. Natl. Acad. Sci. U.S.A. 105:12028-12033(2008) · Mapped (3) |
| Relationship of C-reactive protein with hypertension and interactions between increased C-reactive protein and other risk factors on hypertension in Mongolian people, China. Xu T., Ju Z., Tong W., Hu W., Liu Y., Zhao L., Zhang Y.
Circ. J. 72:1324-1328(2008) · Mapped (3) |
| Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2. Bersenev A., Wu C., Balcerek J., Tong W.
J. Clin. Invest. 118:2832-2844(2008) · Mapped (7) |
| Rosiglitazone, a PPAR gamma agonist, attenuates inflammation after surgical brain injury in rodents. Hyong A., Jadhav V., Lee S., Tong W., Rowe J., Zhang J.H., Tang J.
Brain Res. 1215:218-224(2008) · Mapped (1) |
| Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance. Mochel F., Knight M.A., Tong W.-H., Hernandez D., Ayyad K., Taivassalo T., Andersen P.M., Singleton A., Rouault T.A., Fischbeck K.H. et al.
Am. J. Hum. Genet. 82:652-660(2008) · UniProtKB (2) · Mapped (3) |
| Multiple risk factor clustering and risk of hypertension in the Mongolian ethnic population of China. Ying C.Q., Fu S.B., Xu Q., Tong W.J., Fang M.W., Wu Z.L., Qiu C.C., Zhang Y.H.
Biomed. Environ. Sci. 20:381-385(2007) · Mapped (4) |
| Signals emanating from the membrane proximal region of the thrombopoietin receptor (mpl) support hematopoietic stem cell self-renewal. Tong W., Ibarra Y.M., Lodish H.F.
Exp. Hematol. 35:1447-1455(2007) · Mapped (12) |
| Analysis of genetic variants of the poly(ADP-ribose) polymerase-1 gene in breast cancer in French patients. Cao W.H., Wang X., Frappart L., Rigal D., Wang Z.Q., Shen Y., Tong W.M.
Mutat. Res. 632:20-28(2007) · Mapped (9) |
| Haploinsufficiency of poly(ADP-ribose) polymerase-1-mediated poly(ADP-ribosyl)ation for centrosome duplication. Kanai M., Tong W.M., Wang Z.Q., Miwa M.
Biochem. Biophys. Res. Commun. 359:426-430(2007) · Mapped (9) |
| Identification and characterization of a novel p42.3 gene as tumor-specific and mitosis phase-dependent expression in gastric cancer. Xu X., Li W., Fan X., Liang Y., Zhao M., Zhang J., Liang Y., Tong W., Wang J., Yang W. et al.
Oncogene 26:7371-7379(2007) · UniProtKB (1) |
| C620R mutation of the murine ret proto-oncogene: loss of function effect in homozygotes and possible gain of function effect in heterozygotes. Yin L., Puliti A., Bonora E., Evangelisti C., Conti V., Tong W.M., Medard J.J., Lavoue M.F., Forey N., Wang L.C. et al.
Int. J. Cancer 121:292-300(2007) · Mapped (2) |
| Identification of genes differentially expressed in human primary lung squamous cell carcinoma. Liu Y., Sun W., Zhang K., Zheng H., Ma Y., Lin D., Zhang X., Feng L., Lei W., Zhang Z. et al.
Lung Cancer 56:307-317(2007) · Mapped (15) |
| JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis. Scott L.M., Tong W., Levine R.L., Scott M.A., Beer P.A., Stratton M.R., Futreal P.A., Erber W.N., McMullin M.F., Harrison C.N. et al.
N. Engl. J. Med. 356:459-468(2007) · UniProtKB (1) · Mapped (5) |
| Poly(ADP-ribose) polymerase-1 plays a role in suppressing mammary tumourigenesis in mice. Tong W.M., Yang Y.G., Cao W.H., Galendo D., Frappart L., Shen Y., Wang Z.Q.
Oncogene 26:3857-3867(2007) · Mapped (19) |
| The membrane-proximal region of the thrombopoietin receptor confers its high surface expression by JAK2-dependent and -independent mechanisms. Tong W., Sulahian R., Gross A.W., Hendon N., Lodish H.F., Huang L.J.
J. Biol. Chem. 281:38930-38940(2006) · Mapped (9) |
| Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion. Zhang J., He X.C., Tong W.G., Johnson T., Wiedemann L.M., Mishina Y., Feng J.Q., Li L.
Stem Cells 24:2826-2839(2006) · Mapped (2) |
| Hepatitis C virus non-structural protein NS5A interacts with FKBP38 and inhibits apoptosis in Huh7 hepatoma cells. Wang J., Tong W., Zhang X., Chen L., Yi Z., Pan T., Hu Y., Xiang L., Yuan Z.
FEBS Lett. 580:4392-4400(2006) · UniProtKB (2) · Mapped (140) |
| A novel function of DNA repair molecule Nbs1 in terminal differentiation of the lens fibre cells and cataractogenesis. Yang Y.G., Frappart P.O., Frappart L., Wang Z.Q., Tong W.M.
DNA Repair (Amst.) 5:885-893(2006) · Mapped (3) |
| Aflatoxin-B exposure does not lead to p53 mutations but results in enhanced liver cancer of Hupki (human p53 knock-in) mice. Tong W.M., Lee M.K., Galendo D., Wang Z.Q., Sabapathy K.
Int. J. Cancer 119:745-749(2006) · Mapped (10) |
| Roles of the mammalian cytosolic cysteine desulfurase, ISCS, and scaffold protein, ISCU, in iron-sulfur cluster assembly. Li K., Tong W.H., Hughes R.M., Rouault T.A.
J. Biol. Chem. 281:12344-12351(2006) · Mapped (14) |
| Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis. Tong W.H., Rouault T.A.
Cell Metab. 3:199-210(2006) · Mapped (5) |
| Complete loss of iron regulatory proteins 1 and 2 prevents viability of murine zygotes beyond the blastocyst stage of embryonic development. Smith S.R., Ghosh M.C., Ollivierre-Wilson H., Hang Tong W., Rouault T.A.
Blood Cells Mol. Dis. 36:283-287(2006) · Mapped (4) |
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