19 results for author:"Thummel K." in Literature citations
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| Intestinal CYP3A4 and midazolam disposition in vivo associate with VDR polymorphisms and show seasonal variation. Thirumaran R.K., Lamba J.K., Kim R.B., Urquhart B.L., Gregor J.C., Chande N., Fan Y., Qi A., Cheng C., Thummel K.E. et al. Biochem. Pharmacol. 84:104-112(2012) · Mapped (6) |
| Pharmacogenomic trial design: use of a PK/PD model to explore warfarin dosing interventions through clinical trial simulation. Salinger D.H., Shen D.D., Thummel K., Wittkowsky A.K., Vicini P., Veenstra D.L. Pharmacogenet. Genomics 19:965-971(2009) · Mapped (7) |
| Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk. Reding K.W., Li C.I., Weiss N.S., Chen C., Carlson C.S., Duggan D., Thummel K.E., Daling J.R., Malone K.E. Am. J. Epidemiol. 170:1241-1249(2009) · Mapped (22) |
| Genetic polymorphisms in the catechol estrogen metabolism pathway and breast cancer risk. Reding K.W., Weiss N.S., Chen C., Li C.I., Carlson C.S., Wilkerson H.W., Farin F.M., Thummel K.E., Daling J.R., Malone K.E. Cancer Epidemiol. Biomarkers Prev. 18:1461-1467(2009) · Mapped (27) |
| Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease. Smith H.E., Jones J.P., Kalhorn T.F., Farin F.M., Stapleton P.L., Davis C.L., Perkins J.D., Blough D.K., Hebert M.F., Thummel K.E. et al. Pharmacogenet. Genomics 18:943-953(2008) · Mapped (5) |
| Influence of CYP3A5 genotype on the pharmacokinetics and pharmacodynamics of the cytochrome P4503A probes alfentanil and midazolam. Kharasch E.D., Walker A., Isoherranen N., Hoffer C., Sheffels P., Thummel K., Whittington D., Ensign D. Clin. Pharmacol. Ther. 82:410-426(2007) · Mapped (12) |
| Simultaneous measurement of in vivo P-glycoprotein and cytochrome P450 3A activities. Kirby B., Kharasch E.D., Thummel K.T., Narang V.S., Hoffer C.J., Unadkat J.D. J Clin Pharmacol 46:1313-1319(2006) · Mapped (9) |
| The dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor. Zhou C., Poulton E.J., Grun F., Bammler T.K., Blumberg B., Thummel K.E., Eaton D.L. Mol. Pharmacol. 71:220-229(2007) · Mapped (8) |
| Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation. Zhou C., Tabb M.M., Nelson E.L., Grun F., Verma S., Sadatrafiei A., Lin M., Mallick S., Forman B.M., Thummel K.E. et al. J. Clin. Invest. 116:2280-2289(2006) · Mapped (11) |
| Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. Zhou C., Assem M., Tay J.C., Watkins P.B., Blumberg B., Schuetz E.G., Thummel K.E. J. Clin. Invest. 116:1703-1712(2006) · Mapped (22) |
| Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose. Rieder M.J., Reiner A.P., Gage B.F., Nickerson D.A., Eby C.S., McLeod H.L., Blough D.K., Thummel K.E., Veenstra D.L., Rettie A.E. N. Engl. J. Med. 352:2285-2293(2005) · Mapped (2) |
| Association between ABCB1 (multidrug resistance transporter) genotype and post-liver transplantation renal dysfunction in patients receiving calcineurin inhibitors. Hebert M.F., Dowling A.L., Gierwatowski C., Lin Y.S., Edwards K.L., Davis C.L., Marsh C.L., Schuetz E.G., Thummel K.E. Pharmacogenetics 13:661-674(2003) · Mapped (9) |
| CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease. Emery M.G., Fisher J.M., Chien J.Y., Kharasch E.D., Dellinger E.P., Kowdley K.V., Thummel K.E. Hepatology 38:428-435(2003) · Mapped (4) |
| CYP3A5 genotype predicts renal CYP3A activity and blood pressure in healthy adults. Givens R.C., Lin Y.S., Dowling A.L., Thummel K.E., Lamba J.K., Schuetz E.G., Stewart P.W., Watkins P.B. J. Appl. Physiol. 95:1297-1300(2003) · Mapped (12) |
| Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine. Zamber C.P., Lamba J.K., Yasuda K., Farnum J., Thummel K., Schuetz J.D., Schuetz E.G. Pharmacogenetics 13:19-28(2003) · UniProtKB (1) |
| Common allelic variants of cytochrome P4503A4 and their prevalence in different populations. Lamba J.K., Lin Y.S., Thummel K., Daly A., Watkins P.B., Strom S., Zhang J., Schuetz E.G. Pharmacogenetics 12:121-132(2002) · UniProtKB (1) |
| The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants. Zhang J., Kuehl P., Green E.D., Touchman J.W., Watkins P.B., Daly A., Hall S.D., Maurel P., Relling M., Brimer C. et al. Pharmacogenetics 11:555-572(2001) · UniProtKB (1) |
| Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Kuehl P., Zhang J., Lin Y., Lamba J., Assem M., Schuetz J., Watkins P.B., Daly A., Wrighton S.A., Hall S.D. et al. Nat. Genet. 27:383-391(2001) · UniProtKB (3) |
| Purification of macaque liver flavin-containing monooxygenase: a form of the enzyme related immunochemically to an isozyme expressed selectively in adult human liver. Sadeque A.J., Thummel K.E., Rettie A.E. Biochim. Biophys. Acta 1162:127-134(1993) · UniProtKB (1) |