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Septin filament formation is essential in budding yeast.

McMurray M.A., Bertin A., Garcia G., Lam L., Nogales E., Thorner J.

Dev. Cell 20:540-549(2011) · Mapped (8)

Single-cell analysis reveals that insulation maintains signaling specificity between two yeast MAPK pathways with common components.

Patterson J.C., Klimenko E.S., Thorner J.

Sci Signal 3:ra75-ra75(2010) · Mapped (7)

Phosphatidylinositol-4,5-bisphosphate promotes budding yeast septin filament assembly and organization.

Bertin A., McMurray M.A., Thai L., Garcia G., Votin V., Grob P., Allyn T., Thorner J., Nogales E.

J. Mol. Biol. 404:711-731(2010) · Mapped (4)

Dynamic localization of Fus3 mitogen-activated protein kinase is necessary to evoke appropriate responses and avoid cytotoxic effects.

Chen R.E., Patterson J.C., Goupil L.S., Thorner J.

Mol. Cell. Biol. 30:4293-4307(2010) · Mapped (4)

Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling.

Garrenton L.S., Stefan C.J., McMurray M.A., Emr S.D., Thorner J.

Proc. Natl. Acad. Sci. U.S.A. 107:11805-11810(2010) · Mapped (5)

Systematic epistasis analysis of the contributions of protein kinase A- and mitogen-activated protein kinase-dependent signaling to nutrient limitation-evoked responses in the yeast Saccharomyces cerevisiae.

Chen R.E., Thorner J.

Genetics 185:855-870(2010) · Mapped (11)

A protein kinase network regulates the function of aminophospholipid flippases.

Roelants F.M., Baltz A.G., Trott A.E., Fereres S., Thorner J.

Proc. Natl. Acad. Sci. U.S.A. 107:34-39(2010) · UniProtKB (2) · Mapped (10)

Septins: molecular partitioning and the generation of cellular asymmetry.

McMurray M.A., Thorner J.

Cell Div 4:18-18(2009) · Mapped (16)

ABC transporter Pdr10 regulates the membrane microenvironment of Pdr12 in Saccharomyces cerevisiae.

Rockwell N.C., Wolfger H., Kuchler K., Thorner J.

J. Membr. Biol. 229:27-52(2009) · Mapped (15)

Reuse, replace, recycle. Specificity in subunit inheritance and assembly of higher-order septin structures during mitotic and meiotic division in budding yeast.

McMurray M.A., Thorner J.

Cell Cycle 8:195-203(2009) · Mapped (7)

Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence.

Garrenton L.S., Braunwarth A., Irniger S., Hurt E., Kunzler M., Thorner J.

Mol. Cell. Biol. 29:582-601(2009) · Mapped (6)

Stress resistance and signal fidelity independent of nuclear MAPK function.

Westfall P.J., Patterson J.C., Chen R.E., Thorner J.

Proc. Natl. Acad. Sci. U.S.A. 105:12212-12217(2008) · Mapped (10)

Septin stability and recycling during dynamic structural transitions in cell division and development.

McMurray M.A., Thorner J.

Curr. Biol. 18:1203-1208(2008) · Mapped (2)

Saccharomyces cerevisiae septins: supramolecular organization of heterooligomers and the mechanism of filament assembly.

Bertin A., McMurray M.A., Grob P., Park S.S., Garcia G., Patanwala I., Ng H.L., Alber T., Thorner J., Nogales E.

Proc. Natl. Acad. Sci. U.S.A. 105:8274-8279(2008) · Mapped (4)

Membrane-active compounds activate the transcription factors Pdr1 and Pdr3 connecting pleiotropic drug resistance and membrane lipid homeostasis in saccharomyces cerevisiae.

Schuller C., Mamnun Y.M., Wolfger H., Rockwell N., Thorner J., Kuchler K.

Mol. Biol. Cell 18:4932-4944(2007) · Mapped (6)

Structural insights into activation of phosphatidylinositol 4-kinase (Pik1) by yeast frequenin (Frq1).

Strahl T., Huttner I.G., Lusin J.D., Osawa M., King D., Thorner J., Ames J.B.

J. Biol. Chem. 282:30949-30959(2007) · UniProtKB (1) · Mapped (1)

Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae.

Chen R.E., Thorner J.

Biochim. Biophys. Acta 1773:1311-1340(2007) · Mapped (68)

Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae.

Strahl T., Thorner J.

Biochim. Biophys. Acta 1771:353-404(2007) · Mapped (14)

DEP-domain-mediated regulation of GPCR signaling responses.

Ballon D.R., Flanary P.L., Gladue D.P., Konopka J.B., Dohlman H.G., Thorner J.

Cell 126:1079-1093(2006) · Mapped (2)

Analysis of mitogen-activated protein kinase signaling specificity in response to hyperosmotic stress: use of an analog-sensitive HOG1 allele.

Westfall P.J., Thorner J.

Eukaryot. Cell 5:1215-1228(2006) · UniProtKB (1) · Mapped (1)

Direct phosphorylation and activation of a Nim1-related kinase Gin4 by Elm1 in budding yeast.

Asano S., Park J.E., Yu L.R., Zhou M., Sakchaisri K., Park C.J., Kang Y.H., Thorner J., Veenstra T.D., Lee K.S.

J. Biol. Chem. 281:27090-27098(2006) · Mapped (5)

Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain.

Garrenton L.S., Young S.L., Thorner J.

Genes Dev. 20:1946-1958(2006) · Mapped (2)

Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export.

Weirich C.S., Erzberger J.P., Flick J.S., Berger J.M., Thorner J., Weis K.

Nat. Cell Biol. 8:668-676(2006) · Mapped (7)

The RA domain of Ste50 adaptor protein is required for delivery of Ste11 to the plasma membrane in the filamentous growth signaling pathway of the yeast Saccharomyces cerevisiae.

Truckses D.M., Bloomekatz J.E., Thorner J.

Mol. Cell. Biol. 26:912-928(2006) · UniProtKB (1) · Mapped (4)

Yeast phosphatidylinositol 4-kinase, Pik1, has essential roles at the Golgi and in the nucleus.

Strahl T., Hama H., DeWald D.B., Thorner J.

J. Cell Biol. 171:967-979(2005) · Mapped (3)

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