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Progressive degeneration of human neural stem cells caused by pathogenic LRRK2.

Liu G.H., Qu J., Suzuki K., Nivet E., Li M., Montserrat N., Yi F., Xu X., Ruiz S., Zhang W. et al.

Nature 491:603-607(2012) · Mapped (4)

Canonical and atypical E2Fs regulate the mammalian endocycle.

Chen H.Z., Ouseph M.M., Li J., Pecot T., Chokshi V., Kent L., Bae S., Byrne M., Duran C., Comstock G. et al.

Nat. Cell Biol. 14:1192-1202(2012) · UniProtKB (2) · Mapped (14)

Immunohistochemistry is highly sensitive and specific for the detection of V600E BRAF mutation in melanoma.

Long G.V., Wilmott J.S., Capper D., Preusser M., Zhang Y.E., Thompson J.F., Kefford R.F., von Deimling A., Scolyer R.A.

Am. J. Surg. Pathol. 37:61-65(2013) · Mapped (3)

EC144 is a potent inhibitor of the heat shock protein 90.

Shi J., Van de Water R., Hong K., Lamer R.B., Weichert K.W., Sandoval C.M., Kasibhatla S.R., Boehm M.F., Chao J., Lundgren K. et al.

J. Med. Chem. 55:7786-7795(2012) · Mapped (1)

Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1.

Singh N., Basnet H., Wiltshire T.D., Mohammad D.H., Thompson J.R., Heroux A., Botuyan M.V., Yaffe M.B., Couch F.J., Rosenfeld M.G. et al.

Proc. Natl. Acad. Sci. U.S.A. 109:14381-14386(2012) · UniProtKB (1) · Mapped (39)

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.

Hartz S.M., Short S.E., Saccone N.L., Culverhouse R., Chen L., Schwantes-An T.H., Coon H., Han Y., Stephens S.H., Sun J. et al.

Arch. Gen. Psychiatry 69:854-860(2012) · Mapped (3)

PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.

Cui G., Park S., Badeaux A.I., Kim D., Lee J., Thompson J.R., Yan F., Kaneko S., Yuan Z., Botuyan M.V. et al.

Nat. Struct. Mol. Biol. 19:916-924(2012) · UniProtKB (2) · Mapped (35)

Complete genome sequence of a new circular DNA virus from grapevine.

Krenz B., Thompson J.R., Fuchs M., Perry K.L.

J. Virol. 86:7715-7715(2012) · UniProtKB (1)

Hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5) communicates cellular iron and oxygen availability by distinct mechanisms.

Chollangi S., Thompson J.W., Ruiz J.C., Gardner K.H., Bruick R.K.

J. Biol. Chem. 287:23710-23717(2012) · Mapped (1)

Distinguishing clinicopathologic features of patients with V600E and V600K BRAF-mutant metastatic melanoma.

Menzies A.M., Haydu L.E., Visintin L., Carlino M.S., Howle J.R., Thompson J.F., Kefford R.F., Scolyer R.A., Long G.V.

Clin. Cancer Res. 18:3242-3249(2012) · Mapped (3)

Atypical E2F repressors and activators coordinate placental development.

Ouseph M.M., Li J., Chen H.Z., Pecot T., Wenzel P., Thompson J.C., Comstock G., Chokshi V., Byrne M., Forde B. et al.

Dev. Cell 22:849-862(2012) · UniProtKB (2) · Mapped (140)

APOBEC2 is a monomer in solution: implications for APOBEC3G models.

Krzysiak T.C., Jung J., Thompson J., Baker D., Gronenborn A.M.

Biochemistry 51:2008-2017(2012) · Mapped (4)

Proteomic analysis of mammalian primary cilia.

Ishikawa H., Thompson J., Yates J.R., Marshall W.F.

Curr. Biol. 22:414-419(2012) · Mapped (24)

Ion and solute transport by Prestin in Drosophila and Anopheles.

Hirata T., Czapar A., Brin L., Haritonova A., Bondeson D.P., Linser P., Cabrero P., Thompson J., Dow J.A., Romero M.F.

J. Insect Physiol. 58:563-569(2012) · Mapped (30)

Vena cava and aortic smooth muscle cells express transglutaminases 1 and 4 in addition to transglutaminase 2.

Johnson K.B., Petersen-Jones H., Thompson J.M., Hitomi K., Itoh M., Bakker E.N., Johnson G.V., Colak G., Watts S.W.

Am. J. Physiol. Heart Circ. Physiol. 302:H1355-66(2012) · Mapped (2)

Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.

Su D., Hu Q., Li Q., Thompson J.R., Cui G., Fazly A., Davies B.A., Botuyan M.V., Zhang Z., Mer G.

Nature 483:104-107(2012) · UniProtKB (1)

Sputum matrix metalloproteinase-12 in patients with chronic obstructive pulmonary disease and asthma: relationship to disease severity.

Chaudhuri R., McSharry C., Brady J., Donnelly I., Grierson C., McGuinness S., Jolly L., Weir C.J., Messow C.M., Spears M. et al.

J. Allergy Clin. Immunol. 129:655-663.e8(2012) · Mapped (3)

Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations.

Snowden J.S., Rollinson S., Thompson J.C., Harris J.M., Stopford C.L., Richardson A.M., Jones M., Gerhard A., Davidson Y.S., Robinson A. et al.

Brain 135:693-708(2012) · Mapped (2)

Structural and molecular characterization of iron-sensing hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5).

Thompson J.W., Salahudeen A.A., Chollangi S., Ruiz J.C., Brautigam C.A., Makris T.M., Lipscomb J.D., Tomchick D.R., Bruick R.K.

J. Biol. Chem. 287:7357-7365(2012) · UniProtKB (1) · Mapped (1)

Metabolism of sugars by genetically diverse species of oral Leptotrichia.

Thompson J., Pikis A.

Mol. Oral. Microbiol. 27:34-44(2012) · UniProtKB (2)

Histone H3 lysine 14 acetylation is required for activation of a DNA damage checkpoint in fission yeast.

Wang Y., Kallgren S.P., Reddy B.D., Kuntz K., Lopez-Maury L., Thompson J., Watt S., Ma C., Hou H., Shi Y. et al.

J. Biol. Chem. 287:4386-4393(2012) · UniProtKB (7)

SOX2 contributes to melanoma cell invasion.

Girouard S.D., Laga A.C., Mihm M.C., Scolyer R.A., Thompson J.F., Zhan Q., Widlund H.R., Lee C.W., Murphy G.F.

Lab. Invest. 92:362-370(2012) · Mapped (3)

Synthesis and biological evaluation of substituted pyrazoles as blockers of divalent metal transporter 1 (DMT1).

Cadieux J.A., Zhang Z., Mattice M., Brownlie-Cutts A., Fu J., Ratkay L.G., Kwan R., Thompson J., Sanghara J., Zhong J. et al.

Bioorg. Med. Chem. Lett. 22:90-95(2012) · Mapped (8)

Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium.

Zennadi R., Whalen E.J., Soderblom E.J., Alexander S.C., Thompson J.W., Dubois L.G., Moseley M.A., Telen M.J.

Blood 119:1217-1227(2012) · Mapped (11)

Molecular basis for the association of microcephalin (MCPH1) protein with the cell division cycle protein 27 (Cdc27) subunit of the anaphase-promoting complex.

Singh N., Wiltshire T.D., Thompson J.R., Mer G., Couch F.J.

J. Biol. Chem. 287:2854-2862(2012) · UniProtKB (3) · Mapped (42)

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