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The catalytic mechanism of the hotdog-fold enzyme superfamily 4-hydroxybenzoyl-CoA thioesterase from Arthrobacter sp. strain SU.

Song F., Thoden J.B., Zhuang Z., Latham J., Trujillo M., Holden H.M., Dunaway-Mariano D.

Biochemistry 51:7000-7016(2012) · Mapped (1)

Catalytic Mechanism of Perosamine N-Acetyltransferase Revealed by High-Resolution X-ray Crystallographic Studies and Kinetic Analyses.

Thoden J.B., Reinhardt L.A., Cook P.D., Menden P., Cleland W.W., Holden H.M.

Biochemistry 51:3433-3444(2012) · UniProtKB (1)

Biochemical and structural characterization of WlbA from Bordetella pertussis and Chromobacterium violaceum: enzymes required for the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid.

Thoden J.B., Holden H.M.

Biochemistry 50:1483-1491(2011) · UniProtKB (2)

Structural and functional studies of WlbA: a dehydrogenase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid.

Thoden J.B., Holden H.M.

Biochemistry 49:7939-7948(2010) · UniProtKB (2)

Molecular architecture of a C-3'-methyltransferase involved in the biosynthesis of D-tetronitrose.

Bruender N.A., Thoden J.B., Kaur M., Avey M.K., Holden H.M.

Biochemistry 49:5891-5898(2010) · UniProtKB (1)

Molecular structure of WlbB, a bacterial N-acetyltransferase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid .

Thoden J.B., Holden H.M.

Biochemistry 49:4644-4653(2010) · UniProtKB (1)

X-ray structure of kijd3, a key enzyme involved in the biosynthesis of D-kijanose.

Bruender N.A., Thoden J.B., Holden H.M.

Biochemistry 49:3517-3524(2010) · UniProtKB (1)

Structural and functional studies of Aspergillus clavatus N(5)-carboxyaminoimidazole ribonucleotide synthetase .

Thoden J.B., Holden H.M., Paritala H., Firestine S.M.

Biochemistry 49:752-760(2010) · UniProtKB (1)

Structural and functional studies of QdtC: an N-acetyltransferase required for the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose.

Thoden J.B., Cook P.D., Schaffer C., Messner P., Holden H.M.

Biochemistry 48:2699-2709(2009) · UniProtKB (1)

Structural analysis of QdtB, an aminotransferase required for the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose.

Thoden J.B., Schaffer C., Messner P., Holden H.M.

Biochemistry 48:1553-1561(2009) · UniProtKB (1)

Structural analysis of the active site geometry of N5-carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli.

Thoden J.B., Holden H.M., Firestine S.M.

Biochemistry 47:13346-13353(2008) · Mapped (1)

The interaction between an acidic transcriptional activator and its inhibitor. The molecular basis of Gal4p recognition by Gal80p.

Thoden J.B., Ryan L.A., Reece R.J., Holden H.M.

J. Biol. Chem. 283:30266-30272(2008) · Mapped (4)

Active site geometry of glucose-1-phosphate uridylyltransferase.

Thoden J.B., Holden H.M.

Protein Sci. 16:1379-1388(2007) · UniProtKB (1)

The x-ray structure of dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase.

Davis M.L., Thoden J.B., Holden H.M.

J. Biol. Chem. 282:19227-19236(2007) · UniProtKB (1)

Molecular architecture of DesV from Streptomyces venezuelae: a PLP-dependent transaminase involved in the biosynthesis of the unusual sugar desosamine.

Burgie E.S., Thoden J.B., Holden H.M.

Protein Sci. 16:887-896(2007) · UniProtKB (1)

The molecular architecture of glucose-1-phosphate uridylyltransferase.

Thoden J.B., Holden H.M.

Protein Sci. 16:432-440(2007) · Mapped (1)

Understanding a transcriptional paradigm at the molecular level. The structure of yeast Gal80p.

Thoden J.B., Sellick C.A., Reece R.J., Holden H.M.

J. Biol. Chem. 282:1534-1538(2007) · Mapped (2)

The structure of GDP-4-keto-6-deoxy-D-mannose-3-dehydratase: a unique coenzyme B6-dependent enzyme.

Cook P.D., Thoden J.B., Holden H.M.

Protein Sci. 15:2093-2106(2006) · UniProtKB (1)

Functional significance of Glu-77 and Tyr-137 within the active site of isoaspartyl dipeptidase.

Marti-Arbona R., Thoden J.B., Holden H.M., Raushel F.M.

Bioorg. Chem. 33:448-458(2005) · UniProtKB (1)

Molecular structure of Saccharomyces cerevisiae Gal1p, a bifunctional galactokinase and transcriptional inducer.

Thoden J.B., Sellick C.A., Timson D.J., Reece R.J., Holden H.M.

J. Biol. Chem. 280:36905-36911(2005) · Mapped (2)

The molecular architecture of human N-acetylgalactosamine kinase.

Thoden J.B., Holden H.M.

J. Biol. Chem. 280:32784-32791(2005) · UniProtKB (1) · Mapped (3)

Mechanism of the reaction catalyzed by isoaspartyl dipeptidase from Escherichia coli.

Marti-Arbona R., Fresquet V., Thoden J.B., Davis M.L., Holden H.M., Raushel F.M.

Biochemistry 44:7115-7124(2005) · UniProtKB (1)

The molecular architecture of galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae.

Thoden J.B., Holden H.M.

J. Biol. Chem. 280:21900-21907(2005) · Mapped (1)

Functional characterization of the K257R and G319E-hGALE alleles found in patients with ostensibly peripheral epimerase deficiency galactosemia.

Wasilenko J., Lucas M.E., Thoden J.B., Holden H.M., Fridovich-Keil J.L.

Mol. Genet. Metab. 84:32-38(2005) · UniProtKB (1)

Molecular structure of human galactokinase: implications for type II galactosemia.

Thoden J.B., Timson D.J., Reece R.J., Holden H.M.

J. Biol. Chem. 280:9662-9670(2005) · UniProtKB (1) · Mapped (4)

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